Protein Alignment Prp16 and CG1582

DIOPT Version :10

• Sequence 1: NP_572947.1
• Gene: Prp16 / 32373
• FlyBaseID: FBgn0026713
• Length: 1222
• Species: Drosophila melanogaster
• Sequence 2: NP_572663.1
• Gene: CG1582 / 32021
• FlyBaseID: FBgn0030246
• Length: 1288
• Species: Drosophila melanogaster
• Alignment Length: 1273
• Identity: 320/1273 - (25%)
• Similarity: 503/1273 - (39%)
• Gaps: 377/1273 - (29%)

  Fly   133 ERLREHIQRDRKRGP-----------VSSTAAEGRDRDRDWDRDRRRDRDRDRDRDRDRRQH--- 183
            |..|:|::....|.|           ..|.||:.:.|..:....|..|..|....|..|:.|
  Fly     3 ESSRKHMEDCFLRSPSDIRTTNVPAAPKSQAADNKSRKTELHVLRLNDESRQMTMDTLRQIHGPE 67

  Fly   184 ---------RERERDRH---RSWDRDRGRDRDRDRSMSERSVHTPREPGTPGGSSGGISNSSWDD 236
                     ::|.|..|   .|:.:|||       ::..:||.             |:|::..:|
  Fly    68 FQLDDISKYKDRGRGGHGVKHSYWQDRG-------TLVVQSVQ-------------GVSSTRGND 112

  Fly   237 EDGEFGQRKSDWDMPTPRRHG-----------NKSGDWSVRSGGSRRNHGRQDD----TVRPTPA 286
            .||:   |...:.:.....:|           :.|||.........|.:.|..|    |:.|...
  Fly   113 SDGD---RLRRYALAKLENYGFQAVHCLEAYEHCSGDTEAALLLLYRRYMRIPDEEQLTLEPPSE 174

  Fly   287 HRYNQWAHGRKRSGATPWGEDPESLDLWEEEQRRLDREW---YNID------------------- 329
            ..........|        |..||:.....|:|..:|.|   :.||
  Fly   175 QEILDMRADEK--------EALESIFDKAYEEREANRVWNLKFRIDHLLAHSPSEVRKAREAVLA 231

  Fly   330 --------------------EGYDDENNPFGGPNSEYFRKREEQLEQKRTKRISAQQRQNNRDNE 374
                                ..:|.:.....||...:....::..|...||:.|..:    .|||
  Fly   232 AAAAAAQAALDKKKKPPLRCRNFDRDGTCKYGPKCRFAHLPQQPTESDTTKKDSVDE----NDNE 292

  Fly   375 LW-------------------------------------------ERNRMLTSGVVTLISVND-- 394
            ||                                           |...:...|:..:.|:.|
  Fly   293 LWFHVEVRFPPGSRYPYEAPFIYLKTTCHDIPHELRLRYARHLYKEAKEICRDGIPCVYSICDLL 357

  Fly   395 DFDEEALERVHLLVHHIIPPFLDGRIVFTKQPEPVVPVKDPTSDMALLARKGSALVRNYRE---- 455
            ..:|:                |.||:..:..|.|                |.|..   |.|
  Fly   358 QSNEQ----------------LAGRLDTSAFPSP----------------KRSLF---YDEPAGG 387

  Fly   456 ----QKERRKAQKKHWELSGTKLGNIMGVQRPQDEDDMRFDKEKDKADYRKDQKFADHMRDQDTG 516
                ..|..::.|......|....|..|.||..:        .:.:.:.|..|:|.:..:::
  Fly   388 GVNPDAEHHQSPKPSHYARGQTSRNDGGHQRNVE--------AQTRENRRLLQQFVERRKEE--- 441

  Fly   517 GKSDFSRKKTISEQRRFLPVFASRQELLNVIRENSVIIIVGETGSGKTTQLTQYLHEDGY----- 576
                  |.:.|.:.|:.||.||..:.:|.:|..:.|::|.||||.||:||:.|::.::.:
  Fly   442 ------RYQKIIDGRKQLPAFAEIERILALIESSPVVVISGETGCGKSTQVPQFILDNWFFRALQ 500

  Fly   577 --SKRGM----IGCTQPRRVAAMSVAKRVSDEMDTQLGEDVGYAIRFEDCTSERTVIKYMTDGIL 635
              :|..:    |.||||||::|:.||:||:.|...::|:.|||.||.|:..|:.|.:.:.|.|||
  Fly   501 LPAKENLPHVEIICTQPRRLSAIGVAERVAAERLDRIGQLVGYQIRLENKVSQSTRLSFCTTGIL 565

  Fly   636 LRESLRDPELDSYSAIIMDEAHERSLSTDVLFGLLREIVARRHDLKLIVTSATMDSSKFATFFGN 700
            ||....||.|.|.:.:|:||.||||..:|.|..:|:.::..|.|||:|:.|||::::.|:.:||.
  Fly   566 LRRLASDPLLGSVTHVIVDEVHERSEESDFLLLILKNLLRERKDLKVILMSATLNAALFSDYFGG 630

  Fly   701 VPTFTIPGRTFPVDVMF------------------------------------------------ 717
            .|...||||||||..:|
  Fly   631 APVLDIPGRTFPVQQLFLEDILEMSDFVMEYDTKYCRKLKKQEQEILERELEYADVQASGEAPGK 695

  Fly   718 -------------------SKNTCE------------DYVESAVKQALQ-VHLTPNEGDMLIFMP 750
                               ||.||:            :.:||.:|..:: .|..|.||.:|||:|
  Fly   696 KIKDEKLTLAETYQRYAEYSKPTCKSIYLMEPMTINPELIESVLKYIVEGSHDWPREGTILIFLP 760

  Fly   751 GQEDIEVTCEVLEERLAEIDNAPALSILPIYSQLPSDLQAKIFQKSSDGLRKCVVATNIAETSLT 815
            |..:|:...:.|.:.......|....::|::|.|..:.||.:|:|:..|.||.|::|||||||:|
  Fly   761 GFGEIQSVHDSLLDNALFSPRAGKFILVPLHSALSGEDQALVFKKAPPGKRKIVLSTNIAETSVT 825

  Fly   816 VDGIIYVIDSGYCKLKVYNPRIGMDALQIYPISQANANQRSGRAGRTGPGQAYRLYTQRQYKDEL 880
            :|..::|:|.|..|.|.::....|::|.:..:|:|||.||.|||||..||....|||..:|:..:
  Fly   826 IDDCVFVVDCGLMKEKCFDSNRNMESLDLVWVSRANAKQRKGRAGRVMPGVCIHLYTSYRYQYHI 890

  Fly   881 LALTVPEIQRTNLANTVLLLKSL------GVVDLLQFHFMDPPPQDNILNSLYQLWILGALDHTG 939
            ||..||||||..|...||.:|:|      ..:.:| ...::.|.:|::|.:|.:|..:||||...
  Fly   891 LAQPVPEIQRVPLEQIVLRIKTLQTFASRNTLSVL-LETLEAPTEDSVLGALTRLRDVGALDAED 954

  Fly   940 ALTTLGRQMAEFPLDPPQCQMLIVACRMGCSAEVLIIVSMLSVPSIFYRPKGREDEADGVREKFQ 1004
            .||.||..:|..|:|....::::......|...||.|.:.||..|.|..|..:..|||..:..|.
  Fly   955 QLTPLGHHLAALPVDVRIGKLMLYGAIFQCLDSVLTIAACLSNKSPFVSPLNKRTEADKCKRMFA 1019

  Fly  1005 RPESDHLTYLNVYQQW----RQNNY--SSTWCNEHFIHIKAMRKVREVRQQLKDIMTQQNLSVIS 1063
            ...|||||.||.|::|    |:.||  |..:.:|||:.:..:..:.:::.|..:::       :|
  Fly  1020 LGNSDHLTVLNAYRKWLDVARRGNYAASRNYASEHFLSLNTLETIADLKYQYLELL-------VS 1077

  Fly  1064 CG---IDWDIVRKCICSAYFYQAARLKGI-----GEYVNLRTGMPCHLHPTSALYGLGTTPDYVV 1120
            .|   ||....||..|.    ....|.|:     |:...|.|.:.|     :|||     |:.|
  Fly  1078 IGFVPIDVPRRRKNACD----NILTLTGVEQNHNGDNNRLLTSLLC-----AALY-----PNIV- 1127

  Fly  1121 YHELIMTA-KEYMQCA----------------TAVDGY 1141
               .|||. :.|:|.|                |..|||
  Fly  1128 ---KIMTPDRVYIQTAGGAVPREPSHHDLRFKTRGDGY 1162

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp16	NP_572947.1	HrpA	534..>1148	CDD:441249	232/736 (32%)
CG1582	NP_572663.1	UBA_like_SF	123..154	CDD:473871	4/30 (13%)
		RWD_DHX57	175..367	CDD:467661	29/219 (13%)
		zf-CCCH	245..272	CDD:459885	3/26 (12%)
		HrpA	452..>1075	CDD:441249	204/623 (33%)
		OB_NTP_bind	1114..1212	CDD:400182	17/63 (27%)