Protein Alignment Prp16 and Dhx33

DIOPT Version :10

• Sequence 1: NP_572947.1
• Gene: Prp16 / 32373
• FlyBaseID: FBgn0026713
• Length: 1222
• Species: Drosophila melanogaster
• Sequence 2: NP_001099272.1
• Gene: Dhx33 / 287464
• RGDID: 1307239
• Length: 698
• Species: Rattus norvegicus
• Alignment Length: 666
• Identity: 281/666 - (42%)
• Similarity: 413/666 - (62%)
• Gaps: 31/666 - (4%)

  Fly   515 TGGKSDFSRKKT--------------ISEQRRFLPVFASRQELLNVIRENSVIIIVGETGSGKTT 565
            :||.:...|::|              :..|||.||:|.:|.:||..:|.....:::|||||||||
  Rat    32 SGGGAGGGRRQTPPLAQPSASPYREALELQRRSLPIFRARGQLLAQLRNLDNAVLIGETGSGKTT 96

  Fly   566 QLTQYLHEDGYSKRGMIGCTQPRRVAAMSVAKRVSDEMDTQLGEDVGYAIRFEDCTSERTVIKYM 630
            |:.|||:|.|.|::|:|..||||||||:|:|.|||||..|:||:.|||.:||||.|||.|.||::
  Rat    97 QIPQYLYEGGISRQGIIAVTQPRRVAAISLATRVSDEKRTELGKLVGYTVRFEDVTSEDTRIKFL 161

  Fly   631 TDGILLRESLRDPELDSYSAIIMDEAHERSLSTDVLFGLLREIVARRHD-----LKLIVTSATMD 690
            |||:||||::.|..|..||.:|:||||||::.||||||:::....||.:     ||:||.|||||
  Rat   162 TDGMLLREAISDSLLRKYSCVILDEAHERTIHTDVLFGVVKTAQKRRKELGKLPLKVIVMSATMD 226

  Fly   691 SSKFATFFGNVPTFTIPGRTFPVDVMFSKNTCEDYVESAVKQALQVHL-TPNEGDMLIFMPGQED 754
            ...|:.:|...|...:.||..|:.:.::|...:||:.:|:....|:|. .|:..|:|:|:.|||:
  Rat   227 VDLFSQYFNGAPVLYLEGRQHPIQIFYTKQPQQDYLHAALVSVFQIHQEAPSSQDILVFLTGQEE 291

  Fly   755 IEV---TCEVLEERLAEIDNAPALSILPIYSQLPSDLQAKIFQKSSDGLRKCVVATNIAETSLTV 816
            ||.   ||..:.:.|.  |..|::.:||:|:.||...|.::||.:..|.||.:::|||||||:|:
  Rat   292 IEAMSKTCRDIAKHLP--DGCPSMLVLPLYASLPYSQQLRVFQGAPKGYRKVIISTNIAETSITI 354

  Fly   817 DGIIYVIDSGYCKLKVYNPRIGMDALQIYPISQANANQRSGRAGRTGPGQAYRLYTQRQYKDELL 881
            .||.||:|:|..|.|.|||..|::.|.:..:|:..|.||:|||||...|..|||||:.:: |:..
  Rat   355 TGIKYVVDTGMVKAKKYNPDSGLEVLAVQRVSKTQAWQRTGRAGREDSGICYRLYTEDEF-DKFE 418

  Fly   882 ALTVPEIQRTNLANTVLLLKSLGVVDLLQFHFMDPPPQDNILNSLYQLWILGALDHTG---ALTT 943
            .:..|||||.|||:.:|.|.::.|.::|.|.||..|..|:|..::.||.:||||:|..   |||.
  Rat   419 KMAAPEIQRCNLASVMLQLLAMKVPNVLTFDFMSRPSPDHIEAAIAQLDLLGALEHKDDQLALTP 483

  Fly   944 LGRQMAEFPLDPPQCQMLIVACRMGCSAEVLIIVSMLSVPSIFYRPKGREDEADGVREKFQRPES 1008
            :||:||.|||:|...:.::::.:..|:.|:|.|||:|||.|:.|.|..|.||...||:||...|.
  Rat   484 IGRKMAAFPLEPKFAKTILLSSKFHCTEEILTIVSLLSVDSVLYNPPARRDEVQSVRKKFISSEG 548

  Fly  1009 DHLTYLNVYQQWRQNNYSSTWCNEHFIHIKAMRKVREVRQQLKDIMTQQNLSVISCGIDWDIVRK 1073
            ||:|.||:|:.::....:..||.|:|::.|.|..|.|||.||:||..:.::.::|...|.:.||:
  Rat   549 DHITLLNIYRTFKNIGGNKDWCKENFVNSKNMLLVAEVRAQLRDICLKMSMPIMSSRGDMESVRR 613

  Fly  1074 CICSAYFYQAARLKGIGEYVNLRTGMPCHLHPTSALYGLGTTPDYVVYHELIMTAKEYMQCATAV 1138
            |:..:.|...|.|:..|.|....|..|..:||:|.|:  ...|..|||..|:.|.|.||:....|
  Rat   614 CLAHSLFMSTAELQPDGTYATTDTHQPVAIHPSSVLF--HCKPACVVYTSLLYTNKCYMRDLCVV 676

  Fly  1139 DGYWLAELGPMFFSVK 1154
            |..||.|..|.:|..|
  Rat   677 DAEWLYEAAPDYFRRK 692

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp16	NP_572947.1	HrpA	534..>1148	CDD:441249	271/625 (43%)
Dhx33	NP_001099272.1	HrpA	64..>534	CDD:441249	214/472 (45%)
		OB_NTP_bind	611..688	CDD:400182	29/78 (37%)