DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment l(1)G0007 and mog-4

DIOPT Version :9

Sequence 1:	NP_572947.1	Gene:	l(1)G0007 / 32373	FlyBaseID:	FBgn0026713	Length:	1222	Species:	Drosophila melanogaster
Sequence 2:	NP_497027.1	Gene:	mog-4 / 175117	WormBaseID:	WBGene00003392	Length:	1008	Species:	Caenorhabditis elegans

Alignment Length:	997	Identity:	380/997 - (38%)
Similarity:	554/997 - (55%)	Gaps:	183/997 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   296 RKRSGATPWGEDPESLDLWEEEQRRLDREWYNIDEGY-------------------DDEN----- 336
            |:.:.|...|  |.:.:|.|:|..||:|. ..:.|.|                   |||.
Worm    68 RQATSARQRG--PTTAELAEQELNRLNRA-VGVLEDYSASSTKTKNVRKRKESSSEDDEAPIKAS 129

  Fly   337 ------NPFGGPNSE------------------YFRKREEQLEQKRTKRISAQQRQNNRDNELWE 377
                  .|....:||                  ....|..:.|:.:|:.:..::|.:|:|.|
Worm   130 KPGKSVKPSKSDDSESDIEAMEAKLDADIAERDALAARINKKEKDKTRNVMEKKRDDNKDKE--- 191

  Fly   378 RNRMLTSGVVTLISVNDDFDEEA------------LERVHLLVHHIIPPFLDGRIVFTKQPEPVV 430
                   |     |..|...||:            ||.:..:||
Worm   192 -------G-----SSMDKLREESRRQYLKKRKVDKLEELEAIVH--------------------- 223

  Fly   431 PVKDPTSDMALLARKGSALVRNYREQKERRKAQKKHWELSGTKLGNIMGVQR------------- 482
                  .|..|.||:  .|.:..:...|.||...::.:..| |.|::|.::|
Worm   224 ------DDQTLFARE--KLTKREKADMEYRKKVLEYTKAHG-KAGDVMKMKRYHLPDASTKQIPS 279

  Fly   483 ---PQDEDDMR-------FDKEKDKADY---------RKDQKFADHMRDQDTGGKSDF------- 521
               ..||:|.|       :::|:..|..         ||:|:| :.:.|:    |.||
Worm   280 QYVEDDEEDFRPGGDGAKWEEEQLMASMLHLGAKDAKRKEQEF-ELLLDE----KVDFIQALQMP 339

  Fly   522 ------------SRKKTISEQRRFLPVFASRQELLNVIRENSVIIIVGETGSGKTTQLTQYLHED 574
                        .:|.:|.|.|:.|||:|.|...:..::|:.|:||.|||||||||||.|||:|.
Worm   340 GTNEEVVETEAEKKKMSIEETRKSLPVYAFRDAFIEAVKEHQVLIIEGETGSGKTTQLPQYLYEA 404

  Fly   575 GYSKRG-MIGCTQPRRVAAMSVAKRVSDEMDTQLGEDVGYAIRFEDCTSERTVIKYMTDGILLRE 638
            |:.:.| .|||||||||||||||.||:||:..:||..|||:|||||||||:||:||||||:||||
Worm   405 GFCEGGKRIGCTQPRRVAAMSVAARVADEVGCKLGTQVGYSIRFEDCTSEKTVLKYMTDGMLLRE 469

  Fly   639 SLRDPELDSYSAIIMDEAHERSLSTDVLFGLLREIVARRHDLKLIVTSATMDSSKFATFFGNVPT 703
            .|.:|:|.|||.:::||||||:|.||:||||:::|...|.||||:::|||:|:.||::||.:.|.
Worm   470 FLNEPDLASYSVMMIDEAHERTLHTDILFGLVKDIARFRKDLKLLISSATLDAEKFSSFFDDAPI 534

  Fly   704 FTIPGRTFPVDVMFSKNTCEDYVESAVKQALQVHLT-PNEGDMLIFMPGQEDIEVTCEVLEERLA 767
            |.||||.||||:.:::....|||::|:...:|:||| |..||:|:|:.|||:||...|.|.||..
Worm   535 FRIPGRRFPVDIYYTQAPEADYVDAAIVTIMQIHLTQPLPGDILVFLTGQEEIETVQEALMERSK 599

  Fly   768 EI-DNAPALSILPIYSQLPSDLQAKIFQKSSDGLRKCVVATNIAETSLTVDGIIYVIDSGYCKLK 831
            .: .....|..||:|:.||||||||||:.:....||.|:||||||||:|:|||.||||.|:.|..
Worm   600 ALGSKIKELIPLPVYANLPSDLQAKIFEPTPKDARKVVLATNIAETSVTIDGINYVIDPGFSKQN 664

  Fly   832 VYNPRIGMDALQIYPISQANANQRSGRAGRTGPGQAYRLYTQRQYKDELLALTVPEIQRTNLANT 896
            .::.|.|::.|.:..||:|.||||:|||||||||:.:||||...||.||....:||||||||.|.
Worm   665 SFDARSGVEHLHVVTISKAAANQRAGRAGRTGPGKCFRLYTAWAYKHELEEQPIPEIQRTNLGNV 729

  Fly   897 VLLLKSLGVVDLLQFHFMDPPPQDNILNSLYQLWILGALDHTGALTTLGRQMAEFPLDPPQCQML 961
            ||:|||||:.||:.|.|:|||||:.::.:|.||:.||||:|.|.||.|||:|||||.||...:|:
Worm   730 VLMLKSLGIHDLVHFDFLDPPPQETLVIALEQLYALGALNHRGELTKLGRRMAEFPCDPCMSKMI 794

  Fly   962 IVACRMGCSAEVLIIVSMLSV-PSIFYRPKGREDEADGVREKFQRPESDHLTYLNVYQQWRQNNY 1025
            |.:.:..||.|::.|.:|||. .::|||||.:...||..|:.|..|..||:|.:|||.:|:::::
Worm   795 IASEKYECSEEIVTIAAMLSCNAAVFYRPKAQVIHADSARKGFWSPAGDHITLMNVYNKWQESSF 859

  Fly  1026 SSTWCNEHFIHIKAMRKVREVRQQLKDIMTQQNLSVISCGIDWDIVRKCICSAYFYQAARLKGIG 1090
            |..||.|:::..:.|::.|:||.||..::.:..:...| ..|...:||.|.:.|||..::|...|
Worm   860 SQRWCVENYVQHRTMKRARDVRDQLVGLLERVEIETKS-STDTIKIRKAITAGYFYNVSKLDNTG 923

  Fly  1091 EYVNLRTGMPCHLHPTSALYGLGTTPDYVVYHELIMTAKEYMQCATAVDGYWLAELGPMFFSVKE 1155
            .|..::.....|.||.|.|:  ..||.:|||.||:.|:||:|:..:.::..||.|:.|.::..:|
Worm   924 HYKTVKHKHTTHPHPNSCLF--EETPRWVVYFELVFTSKEFMREMSEIESGWLLEVAPHYYKGRE 986

  Fly  1156 ------------SGRSGREKKK 1165
                        .|:||::.::
Worm   987 LEDATNKKMPKNKGKSGKDLER 1008

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(1)G0007	NP_572947.1	DEXDc	529..715	CDD:214692	115/186 (62%)
		DEXDc	551..689	CDD:238005	92/138 (67%)
		HELICc	722..870	CDD:238034	76/149 (51%)
		HA2	932..1014	CDD:214852	40/82 (49%)
		OB_NTP_bind	1048..1148	CDD:285018	32/99 (32%)
mog-4	NP_497027.1	DTHCT	<103..162	CDD:285332	6/58 (10%)
		DEXDc	370..546	CDD:214692	109/175 (62%)
		DEXDc	381..520	CDD:238005	92/138 (67%)
		Helicase_C	577..696	CDD:278689	61/118 (52%)
		HA2	764..848	CDD:214852	40/83 (48%)
		OB_NTP_bind	872..981	CDD:285018	37/111 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D113216at33208
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100085
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X141
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820