Protein Alignment l(1)G0007 and let-355

DIOPT Version :9

• Sequence 1: NP_572947.1
• Gene: l(1)G0007 / 32373
• FlyBaseID: FBgn0026713
• Length: 1222
• Species: Drosophila melanogaster
• Sequence 2: NP_491604.3
• Gene: let-355 / 172199
• WormBaseID: WBGene00020263
• Length: 856
• Species: Caenorhabditis elegans
• Alignment Length: 985
• Identity: 287/985 - (29%)
• Similarity: 462/985 - (46%)
• Gaps: 235/985 - (23%)

  Fly   314 WEEEQRRLDREWYNID-EGYDDENNP-------------------FGGPNSEYFRKREEQLE--Q 356
            |::::|:     :.|| :|...:.||                   .||...::     :.||  :
 Worm    10 WKKKKRK-----FQIDKDGKKIKPNPGAQISKILQNGKVNGNSRQTGGQEQKF-----QNLEALK 64

  Fly   357 KRTKRISAQQRQNN---RDNELWERNRMLTSGVVTLISVNDDFDEEALERVHLLVHHIIPPFLDG 418
            |:|..:..:::|.|   ::.||......:|:|::.        .|:.:|..
 Worm    65 KKTMLLKKKKKQMNNFQKEEELLSSTFRITNGILK--------KEKKIEVT-------------- 107

  Fly   419 RIVFTKQPE--PVVPVKDPTSDMALLARKGSALVRNYREQKERRKAQKK----HWELSGTKLGNI 477
             .:.|:.|:  |..|:..|::.            :|......|:.:..:    |:|
 Worm   108 -TISTQTPKKLPKTPISTPSNS------------KNATPMSTRKHSSSQQSPPHFE--------- 150

  Fly   478 MGVQRPQDEDDMRFDKEKDKADYRKDQKFADHMRDQDTGGKSDFSRKKTISEQRRFLPVFASRQE 542
                                |:|.|                  |||.:        ||:.|..|:
 Worm   151 --------------------ANYEK------------------FSRPQ--------LPIDAVEQQ 169

  Fly   543 LLNVIRENSVIIIVGETGSGKTTQLTQYLHEDGYSKRGMIGCTQPRRVAAMSVAKRVSDEMDTQL 607
            |:..:.....:|::|||||||:||:.|.....|.:..|.|..||||||||:|:|.||:.||.|.:
 Worm   170 LMYELASQETLIVIGETGSGKSTQVPQLCVRAGIANSGSIAVTQPRRVAAISLASRVATEMGTNI 234

  Fly   608 GEDVGYAIRFEDCTSERTVIKYMTDGILLRESLRDPELDSYSAIIMDEAHERSLSTDVLFGLLRE 672
            |..|||.:|||:.|..:|.|:||||||:||::|..|.||.||.:|:||||||||.:|||..:||:
 Worm   235 GGIVGYHVRFENATCHKTKIEYMTDGIVLRKALVSPLLDKYSCVIIDEAHERSLHSDVLMCILRQ 299

  Fly   673 IVARRHD----LKLIVTSATMDSSKFATFFGNVPTFTIPGRTFPVDVMFSKN-------TCEDYV 726
            ...:|.:    |:||:.|||:.:.||.::|.|.....:.|||||::| |..|       :..|||
 Worm   300 CQDQRRETNNPLRLIIMSATLQAEKFQSYFNNAKVVLVAGRTFPIEV-FHVNPKINKSFSSTDYV 363

  Fly   727 ESAVKQALQVHLTPNEG-DMLIFMPGQEDIEVTCEVLEERLAEID-----NAPALSILPIYSQLP 785
            .:||.....||||..:| |:|:|:.|.|:|    |.:..:|||::     :|..|..:|:|:.|.
 Worm   364 YNAVICVKYVHLTEPKGRDILVFLTGSEEI----EAVASQLAELNGSLPASADVLMPVPLYAALR 424

  Fly   786 SDLQAKIFQKSSDGLRKCVVATNIAETSLTVDGIIYVIDSGYCKLKVYNPRIGMDALQIYPISQA 850
            .:.|.:.|:|:..|.||.:::|||||||:|:.||..|||||..|.|.:.....:|.|:::.:|:|
 Worm   425 PEKQKEAFRKTPQGARKVIISTNIAETSVTIPGIRVVIDSGKVKTKRFEAFNRIDVLKVHNVSKA 489

  Fly   851 NANQRSGRAGRTGPGQAYRLYTQRQYKDELLALTVPEIQRTNLANTVLLLKSLGVVDLLQFHFMD 915
            .|.||:|||||..||:.||||::..: .:..|..:|||.|.||:.|.|.|..||:.:..:...:|
 Worm   490 QAKQRAGRAGRDAPGKCYRLYSREDF-HKFEAENMPEILRCNLSATFLELMKLGMKNPHRLKLID 553

  Fly   916 PPPQDNILNSLYQLWILGALDHTG------ALTTLGRQMAEFPLDPPQCQMLIVACRMGCSAEVL 974
            ||..|||..:|.:|..|||:....      |||.:|.....:||.|...::|..|.:.||..|.:
 Worm   554 PPETDNINAALLELTSLGAIRPVNSDRSKFALTEMGDAFCMYPLPPDHARILFQAQKEGCIMEAI 618

  Fly   975 IIVSMLSVPSIFYRPKGRED-----EADGVREKFQRPESDHLTYLNV-------YQQWR------ 1021
            .||:.:...::|   .|..|     :.|.:|.:|:..|.||:|.|.:       :.|..
 Worm   619 KIVAAMQTDALF---SGAGDSKSDADVDRIRRRFETREGDHITLLKLVLVTNQFFDQLNKKTESD 680

  Fly  1022 ----------QNNYSST---WCNEHFIHIKAMRKVREVRQQLKDIMTQQNLSVISCGIDWDIVRK 1073
                      :..|:.|   :||::.|:.:.::....:.:|||.|..:|.::..:||.|:..:||
 Worm   681 ARYGKANKSLEREYNQTIRKFCNDNMINEQHLKTASMIEEQLKQIAIEQKVTFSTCGADFMKMRK 745

  Fly  1074 CICSAYFYQAARLKGIGEY--------VNLRTGMPCHLHPTSALYGLGTTPDYVVYHELIMTAKE 1130
            .:....|..:.      ||        :.:...:...:||:|.|  ..:.|.|:|:.||:.|...
 Worm   746 ALALGMFLNSC------EYDRQEDRYRLMINPAITLKIHPSSCL--SRSKPAYIVFSELMKTNDL 802

  Fly  1131 YMQCATAVDGYWLAELGPMFFSVKESGRSGREKKKQAAEHLKEMEEQMLKAQHEMEERKQQAAER 1195
            :....|.:||.|:.   |:.          .:.||..|.||.|..|::            |...|
 Worm   803 FALQVTLIDGDWVR---PLI----------SDHKKMRANHLAETTERV------------QQITR 842

  Fly  1196 EEQLATKQEI 1205
            .|..|.|.::
 Worm   843 LEPKAKKAKL 852

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
l(1)G0007	NP_572947.1	DEXDc	529..715	CDD:214692	88/189 (47%)
		DEXDc	551..689	CDD:238005	73/141 (52%)
		HELICc	722..870	CDD:238034	63/153 (41%)
		HA2	932..1014	CDD:214852	27/92 (29%)
		OB_NTP_bind	1048..1148	CDD:285018	27/107 (25%)
let-355	NP_491604.3	HrpA	149..>800	CDD:224557	240/722 (33%)
		DEXDc	180..320	CDD:238005	73/139 (53%)
		Helicase_C	383..500	CDD:278689	47/120 (39%)
		HA2	569..660	CDD:214852	27/93 (29%)
		OB_NTP_bind	712..822	CDD:285018	28/130 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.780