Protein Alignment Prp16 and l(2)37Cb

DIOPT Version :10

• Sequence 1: NP_572947.1
• Gene: Prp16 / 32373
• FlyBaseID: FBgn0026713
• Length: 1222
• Species: Drosophila melanogaster
• Sequence 2: XP_319843.5
• Gene: l(2)37Cb / 1280046
• VectorBaseID: AGAMI1_007561
• Length: 891
• Species: Anopheles gambiae
• Alignment Length: 996
• Identity: 381/996 - (38%)
• Similarity: 552/996 - (55%)
• Gaps: 155/996 - (15%)

  Fly   186 RERDRHRSWDRDRGRDRDRDRSMSERSVHTPREPGTPGGSSGGISNSSWDDEDGEFGQRKSDWDM 250
            :..||.:|:..|...|.:|.|.:.||.                           ||
Mosquito     3 KNTDRRKSYSSDDSSDEERHRDLKERD---------------------------EF--------- 31

  Fly   251 PTPRRHGNKSGDWSVRSGGSRRNHGRQDDTVRPTPAHRYNQWAHGRKRSGATPWGEDPESLDLWE 315
                               |:|...|.:...|...|....:.|...||            |.|..
Mosquito    32 -------------------SKRLKQRDESNTRNVAASSDKRGADAAKR------------LRLET 65

  Fly   316 EEQRRLDREWYNIDEGYDDENNPFGGPNSEYFRK--REEQLEQKRTKRISAQQRQNNRDN----- 373
            .::.:|..|                      .||  |.:.||:::..:: |:...:.||:
Mosquito    66 ADREKLLPE----------------------LRKQSRRQYLEKRKEDKV-AELEADIRDDEYLFP 107

  Fly   374 --ELWERNRMLTSGVVTLISVNDDFDE-EALERVHLLVHHIIPPFLDGRIVFTKQPEPVVPVKDP 435
              |:.||.|........|:.:..|.:: ..||||...                :.|:.|
Mosquito   108 EAEITERERRDREHKKRLLQIAKDHEKARELERVQRY----------------RMPKDV------ 150

  Fly   436 TSDMALLARKGSALVRNYREQKERRK---AQKKHWELS---------GTKLGNIMGVQRPQDEDD 488
                    :||.  :..|.|..||.:   :::|.||..         |:|.......|  |.|.:
Mosquito   151 --------KKGE--MEEYVEVDERERMPHSEQKKWEAEQLASAVYGFGSKDAKERAAQ--QQEYE 203

  Fly   489 MRFDKEKDKADYRKDQKFADHMRDQDTGGKSDFSRKK-TISEQRRFLPVFASRQELLNVIRENSV 552
            :..|   ::.|:.:..:.|...:..|....::..||| ||.|.::.||::..:::|:..|:.:::
Mosquito   204 LLLD---EQIDFVEALQMAGTKKKDDKPELTEAQRKKMTIEETQKSLPIYPFKEDLIAAIQAHNI 265

  Fly   553 IIIVGETGSGKTTQLTQYLHEDGYSKRG-MIGCTQPRRVAAMSVAKRVSDEMDTQLGEDVGYAIR 616
            :||.||||||||||:.|||:|.|::..| .|||||||||||||||.||::||..:||.:|||:||
Mosquito   266 LIIEGETGSGKTTQIPQYLYEAGFTNEGKKIGCTQPRRVAAMSVAARVAEEMAVKLGNEVGYSIR 330

  Fly   617 FEDCTSERTVIKYMTDGILLRESLRDPELDSYSAIIMDEAHERSLSTDVLFGLLREIVARRHDLK 681
            |||||||||||||||||.|.||.|.:|:|.||:.:|:||||||:|.||:||||:::|...|.|||
Mosquito   331 FEDCTSERTVIKYMTDGTLHREFLSEPDLASYAVMIIDEAHERTLHTDILFGLVKDIARFRKDLK 395

  Fly   682 LIVTSATMDSSKFATFFGNVPTFTIPGRTFPVDVMFSKNTCEDYVESAVKQALQVHLTPNEGDML 746
            |:::|||:|:.||:.||...|.|.||||.:|||:.::|....||:::.|...||:|.|...||:|
Mosquito   396 LLISSATLDAEKFSDFFDKAPIFRIPGRRYPVDIFYTKAPEADYIDACVVSVLQIHATQPLGDIL 460

  Fly   747 IFMPGQEDIEVTCEVLEERLAEI-DNAPALSILPIYSQLPSDLQAKIFQKSSDGLRKCVVATNIA 810
            :|:.|||:||...|:|::|:..: .....|.|||||:.||||:|||||:.:....||.::|||||
Mosquito   461 VFLTGQEEIEACQEMLQDRVKRLGSKLKELLILPIYANLPSDMQAKIFEPTPPNARKVILATNIA 525

  Fly   811 ETSLTVDGIIYVIDSGYCKLKVYNPRIGMDALQIYPISQANANQRSGRAGRTGPGQAYRLYTQRQ 875
            |||||:|.||||||.|:.|...:|.|.||:.|.:.|||:|:||||:|||||..||:.:||||...
Mosquito   526 ETSLTIDNIIYVIDPGFAKQNNFNSRTGMETLLVVPISKASANQRAGRAGRVAPGKCFRLYTAWA 590

  Fly   876 YKDELLALTVPEIQRTNLANTVLLLKSLGVVDLLQFHFMDPPPQDNILNSLYQLWILGALDHTGA 940
            |.:||...|||||||.||.|.||:||:||:.|||.|.|:||||...::.:|.||:.||||:|.|.
Mosquito   591 YNNELEDNTVPEIQRINLGNAVLMLKTLGIHDLLHFDFLDPPPHQTLILALEQLYALGALNHHGE 655

  Fly   941 LTTLGRQMAEFPLDPPQCQMLIVACRMGCSAEVLIIVSMLSV-PSIFYRPKGREDEADGVREKFQ 1004
            ||.|||:|||||:||...:||:.:.:..||.|::.|.:|||| .:||||||.:...||..|:.|.
Mosquito   656 LTKLGRRMAEFPVDPMMAKMLLASEKYKCSEEIVSIAAMLSVNGAIFYRPKDKIIHADTARKNFN 720

  Fly  1005 RPESDHLTYLNVYQQWRQNNYSSTWCNEHFIHIKAMRKVREVRQQLKDIMTQQNLSVISCGIDWD 1069
            ....|||:.:.||.||.:::||:.||.|:||..::|::.|:||:||..:|.:..:.::|...|..
Mosquito   721 HRHGDHLSLMQVYNQWVESDYSTQWCYENFIQYRSMKRARDVREQLVGLMQRVEIEMVSGESDTT 785

  Fly  1070 IVRKCICSAYFYQAARLKGIGEYVNLRTGMPCHLHPTSALYGLGTTPDYVVYHELIMTAKEYMQC 1134
            .|||.|.:.|||..|||...|.|..::......:||.|||:  ...|.:::||||:.|.||:|:.
Mosquito   786 NVRKAITAGYFYHVARLSKSGNYKTVKHNQDVMIHPNSALF--EDLPRWLLYHELVFTTKEFMRS 848

  Fly  1135 ATAVDGYWLAELGPMFFSVKE 1155
            ...::..||.|:.|.::..||
Mosquito   849 VIEIESKWLLEVAPHYYKPKE 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp16	NP_572947.1	HrpA	534..>1148	CDD:441249	311/616 (50%)
l(2)37Cb	XP_319843.5	None