Protein Alignment Prp16 and LOC1277999

DIOPT Version :10

• Sequence 1: NP_572947.1
• Gene: Prp16 / 32373
• FlyBaseID: FBgn0026713
• Length: 1222
• Species: Drosophila melanogaster
• Sequence 2: XP_061516783.1
• Gene: LOC1277999 / 1277999
• VectorBaseID: AGAMI1_003902
• Length: 1089
• Species: Anopheles gambiae
• Alignment Length: 837
• Identity: 214/837 - (25%)
• Similarity: 346/837 - (41%)
• Gaps: 231/837 - (27%)

  Fly   531 RRFLPVFASRQELLNVIRENSVIIIVGETGSGKTTQLTQYLHEDGYSKR--GMIGCTQPRRVAAM 593
            |:.||:....:.:|..|:.|.||||.|.||||||||:.|::.|:...:.  ..|.||||||::|:
Mosquito   149 RKSLPIAQFHEIILKCIQHNQVIIISGNTGSGKTTQVPQFILEEAAQQNLPCRIICTQPRRISAV 213

  Fly   594 SVAKRVSDEMDTQLGEDVGYAIRFEDCTSERTVIKYMTDGILLRESL---RDPELDSYSAIIMDE 655
            :|::||..|.:.|||:.|||.||.|......|...:.|:|:|||..:   ....|.:.:.||:||
Mosquito   214 TVSERVCVERNEQLGDTVGYQIRLESRAKSTTNALFCTNGVLLRCLMGKHSSKFLKNVTHIIIDE 278

  Fly   656 AHERSLSTDVLFGLLREIVARRHDLKLIVTSATMDSSKFATFFGNVPTFTIPGRTFPVDVMF--- 717
            .|||...:|.|...|::.:::...||:|:.|||::|..|:.:|.|.|...||||.||::..|
Mosquito   279 VHERDQYSDFLLIALKDKLSKNAHLKIILMSATIESDTFSKYFNNCPVIEIPGRLFPIETFFLED 343

  Fly   718 ----------------------------------------------------------------- 717
                                                                             
Mosquito   344 ILLNVDTSNHNVKDIRKKMMKSFEAQAVERTKPITVNMDDETILLMNDILEVCWIENNPEDFRNF 408

  Fly   718 ---------------------------------------------------------------SK 719
                                                                           ..
Mosquito   409 FTLIEEENISIDFQHTETKMTALMIAAAKGYIAIVQKLLEMGADPSIQEKHNYNAFDWACFVHGS 473

  Fly   720 NTCEDYVESAV-KQALQV----HLTPN-----------------------------------EGD 744
            :||.|.::.|: |..|.|    .|||:                                   ||.
Mosquito   474 STCSDILKQALNKSGLSVPRTMPLTPHSTKQILDAYHTSVGDDRIDHNLIIDVILHICRKHPEGG 538

  Fly   745 MLIFMPGQEDIEVTCEVLEERLAEIDNAPALSILPIYSQLPSDLQAKIFQKSSDGLRKCVVATNI 809
            :|:|:||.|||:....:|.   :::.|...:.:..::|::.:..|..:|:....|:||.:::|||
Mosquito   539 ILVFLPGFEDIQEQYGLLN---SKVSNIHCIRMFMLHSKMQTADQHSVFKPVPSGVRKIILSTNI 600

  Fly   810 AETSLTVDGIIYVIDSGYCKLKVYNPRIGMDALQIYPISQANANQRSGRAGRTGPGQAYRLYTQR 874
            ||||:|:|.::||||||..|.|.|:......:|....||||.|.||:||||||.||..:|||::.
Mosquito   601 AETSITMDDVVYVIDSGKVKQKYYDSLTSTSSLAATWISQACATQRAGRAGRTRPGTCFRLYSRM 665

  Fly   875 QYKDELLALTVPEIQRTNLA----NTVLLLKSLGVVDLLQFHFMDPPPQDNILNSLYQLWILGAL 935
            :: .|:...|:|||.|..|.    .|.|::|...:.:.|. ..:..|...:|..|:..|..:|||
Mosquito   666 RH-SEMDQYTLPEIMRVPLTEICLQTALIIKDESIQEFLN-KAITAPSTTSIKQSIKYLQKVGAL 728

  Fly   936 DHTGALTTLGRQMAEFPLDPPQCQMLIVACRMGCSAEVLIIVSMLSVPSIFYRP--KGREDEADG 998
            |...::|.||..:||.|:|....:||:....:.|...||::|.:||:..:|..|  .|.::.|..
Mosquito   729 DDEESVTDLGYTLAELPVDARLGKMLLYGILLKCYEPVLLVVCILSINDLFVIPPFPGDKERAKK 793

  Fly   999 VREKF-QRPESDHLTYLNVYQQW---RQNNYSSTWCNEHFIHIKAMRKVREVRQQL--------- 1050
            ||:.. :...||....|..||:|   |........||..|::...:..|.|:|.:|
Mosquito   794 VRQDLAENSYSDCYCLLRAYQRWLDARSVQKRKELCNRLFLNHGKLTMVSELRNKLHAHLCSIGV 858

  Fly  1051 ---------KDIMTQQNLSVISCGIDWDIVRKCICSAYFYQAARLKGIGEYVNLRTGMPCHLHPT 1106
                     ||:....|        :|.:|:..:....:...:.|:...:.:..|......:||:
Mosquito   859 VKSYGPGSVKDLNEFAN--------NWSLVKGILLVGLYPNVSYLEKYSKTMKTRFEKKIFIHPS 915

  Fly  1107 SALYG------------LGTTPDYVVYHELIMTAKEYM-QCATAVDGYWLAEL-GPM 1149
            |.:.|            |....:::.:.|...:.:..| :|.|.:....:|.. ||:
Mosquito   916 SVVGGKASKKQKTTDNALCLPSEWITFEEKCKSGRGSMIRCNTVISPITIAIFAGPL 972

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp16	NP_572947.1	HrpA	534..>1148	CDD:441249	211/831 (25%)
LOC1277999	XP_061516783.1	None