Protein Alignment Prp16 and kz

DIOPT Version :10

• Sequence 1: NP_572947.1
• Gene: Prp16 / 32373
• FlyBaseID: FBgn0026713
• Length: 1222
• Species: Drosophila melanogaster
• Sequence 2: XP_312236.6
• Gene: kz / 1273275
• VectorBaseID: AGAMI1_001604
• Length: 1224
• Species: Anopheles gambiae
• Alignment Length: 1102
• Identity: 292/1102 - (26%)
• Similarity: 466/1102 - (42%)
• Gaps: 312/1102 - (28%)

  Fly   315 EEEQRRLDREWYNIDE-GYDDENNPFGGPNSEYFRKREEQLEQKR---TKRISAQQRQNNR---D 372
            :.|.:::..::...|| |..|.:|....|:    :|||.::::.|   ||.:|.:||:...   |
Mosquito    20 DSETKKIKLDFAPGDEYGGQDNSNVLVLPS----KKRETKIKKDRTVVTKILSKKQRKRLEKIVD 80

  Fly   373 NELWERNRMLTSGVVTLISVNDDFDE----EALERVHL--LVHHIIPPFLDGRIVFTKQPEPVVP 431
            .:..:.||  :|.:.:|::|....|:    ..|..|..  |..|..........|...:...|..
Mosquito    81 QKKKKENR--SSLIASLVAVQASKDDLSGFRKLSEVQTKGLKQHFKEQKYGVTYVNNAKEAGVAK 143

  Fly   432 VKDPTSD----MALLARKGSALVRNYREQKERRKAQKKHWELSGTKLGNIMGVQRP---QDEDDM 489
            :|.....    :|||.:.|.|.|.                |:.|....|::|:..|   :||.:.
Mosquito   144 IKSLVGSRRKRLALLRQAGPASVE----------------EVEGEYDPNVVGLNDPSSSEDESEE 192

  Fly   490 RFDKEKDKADYRKDQKFADHMRDQDTGGKSDFSR--KKTISEQ---------------------- 530
            ..::|.::.:.:::::.......:|...:.|.::  :::|:|:
Mosquito   193 EVEEEGEEGNEQEEEESEQESAQEDENEEVDKNQPEQESITEESSKKVENAPPEDVKQPNGEKEK 257

  Fly   531 -----------------------RRFLPVFASRQELLNVIRENSVIIIVGETGSGKTTQLTQYLH 572
                                   |..||:....|.::..|.||.:.|:.||||||||||:.|:|:
Mosquito   258 PTVVDRKPATYIHVERDPAIQAARLKLPILGEEQIIMETISENKITILAGETGSGKTTQIPQFLY 322

  Fly   573 EDGYSKRGMIGCTQPRRVAAMSVAKRVSDEMDTQLGED-VGYAIRFEDCTSERTVIKYMTDGILL 636
            |.||.:||:||.|:||||||:|::|||:.||:  |..| |.|.||:|...::||.||:||||:||
Mosquito   323 EAGYGERGLIGVTEPRRVAAVSMSKRVAHEMN--LSTDVVSYLIRYEGNVTDRTKIKFMTDGVLL 385

  Fly   637 RESLRDPELDSYSAIIMDEAHERSLSTDVLFGLLREIVARR-----HDLKLIVTSATMDSSKFA- 695
            :|...|..|:.||.||:|||||||:.||:|.|||..||..|     :.|::|:.|||:....|.
Mosquito   386 KEIEVDFLLNKYSCIILDEAHERSVYTDILMGLLSRIVRLREKRGNNPLRVIIMSATLRVQDFTE 450

  Fly   696 ---TFFGNVPTFTIPGRTFPVDVMFSKNTCEDYVESAVKQALQVHLTPNEGDMLIFMPGQEDI-- 755
               .|....|...|..|.|||.|.|:|.|.:||:..|..:.:::|....:|.:|:|:.||:::
Mosquito   451 NKKLFLDTPPVINIDSRQFPVTVHFNKTTPDDYLREAFLKTVKIHTKLPDGGILVFLTGQKEVNT 515

  Fly   756 -------------------------EVTCEVLEERLAEIDNA----PA----------------- 774
                                     |...||:.:...|.||.    ||
Mosquito   516 MVRKLRKMFPLRGDKEGVRTGKKVDEKKEEVVRDEEDEFDNVYRGKPAHKPPKAKSSKRQKRDQL 580

  Fly   775 -----------------------------------------------------------LSILPI 780
                                                                       |.:||:
Mosquito   581 PVLPQINLDAYDLPHVDDTEGDRAEENDTASELDSDDDDDELNAANLSASVSELRKSQPLWVLPL 645

  Fly   781 YSQLPSDLQAKIFQKSSDGLRKCVVATNIAETSLTVDGIIYVIDSGYCKLKVYNPRIGMDALQIY 845
            ||.|..|.|..|||...:|.|.||||||:||||||:..|.||:|:|..|.|:|:...|:.|..:.
Mosquito   646 YSMLSPDKQQLIFQPPPEGARLCVVATNVAETSLTIPDIKYVVDTGRQKTKLYDKTTGVTAFVVT 710

  Fly   846 PISQANANQRSGRAGRTGPGQAYRLYTQRQYKDELLALTVPEIQRTNLANTVLLLKSLGVVDLLQ 910
            ..|:|:||||:|||||..||..||||:...:.||.:....||:|:..:...:|.:|.:|:..:|.
Mosquito   711 YTSKASANQRAGRAGRVAPGHCYRLYSSAVFNDEFVEFAPPEVQQKPVDGLMLQMKCMGIDKVLN 775

  Fly   911 FHFMDPPPQDNILNSLYQLWILGALDHT---------------GALTTLGRQMAEFPLDPPQCQM 960
            |.|..||....::::..:|..||||:..               ..:|.|||.||.||:.|...:|
Mosquito   776 FPFPSPPDPVQLMSAEQRLLQLGALEQVIVRNGGQKVQKNQTLTRVTELGRTMAAFPVAPRFGKM 840

  Fly   961 LIVACRMGCSAEVLIIVSMLSVPSIFYRPKGREDEADGVREKFQRPESDHLTYLNVYQQWRQNN- 1024
            |.::.:......|:.:|:.|||..:.        |...:.|:....||.        ::|||..
Mosquito   841 LALSHQHALLPYVICLVAALSVQEVL--------EEVSLSEEANNTESG--------KRWRQKRK 889

  Fly  1025 -YSST------------------------------WCNEHFIHIKAMRKVREVRQQLKDIMTQQN 1058
             ::.|                              :|.|:.|.:||:|::|::|.||.: ....|
Mosquito   890 IWAGTGESLLLGDPMILLKAVGAAEHAHSKGVLEEFCTENGIRLKAIREIRKLRIQLTN-EVNAN 953

  Fly  1059 LSVISCGIDWD----------IVRKCICSAYFYQAARLKGIGEYVNLRTGM-------------- 1099
            |..::..:|.|          ::|:.:......|.|| |.....:.|:|..
Mosquito   954 LLGMNLAVDPDMAPPTATQIRLLRQLLLIGNADQIAR-KLPESDIKLKTDARKLKHAYNLPMIDE 1017

  Fly  1100 PCHLHPTSALYGLGTTPDYVVYHELIMT-------------AKEYMQCATAVDGYWLAELGP 1148
            |..||.:|.|  ....|::|.|.|....             .|.:::..||::..||.:..|
Mosquito  1018 PVFLHASSVL--RREQPEWVCYQEAYEAIVPGVVGEEGSDKTKMFVRGITAIEPDWLPKFVP 1077

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp16	NP_572947.1	HrpA	534..>1148	CDD:441249	242/814 (30%)
kz	XP_312236.6	None