Protein Alignment Prp16 and Dhx29

DIOPT Version :10

• Sequence 1: NP_572947.1
• Gene: Prp16 / 32373
• FlyBaseID: FBgn0026713
• Length: 1222
• Species: Drosophila melanogaster
• Sequence 2: NP_001414443.1
• Gene: Dhx29 / 100362324
• RGDID: 2318361
• Length: 1366
• Species: Rattus norvegicus
• Alignment Length: 1386
• Identity: 320/1386 - (23%)
• Similarity: 565/1386 - (40%)
• Gaps: 363/1386 - (26%)

  Fly    10 HRLEGTAGQETRGGLVIRKPKDAGAGGGGGFKVPQGSMLGLDKLAAKRRAEKERSERLISFKDSE 74
            |:..|.|...........:..:|||.|....|.|..........:| |....::..::.||..:
  Rat     8 HKAPGAAAMRAAVSASRARSAEAGAVGEAQSKKPVARPAPAVPTSA-REPRVKQGPKIYSFNSA- 70

  Fly    75 FDDTGGGSSTPQANASGASSEFAFKKPDTKSFEKLRGQLREHK---DDTPSHTGGVSEKARERLR 136
             :|:||     .||...:..:...   :.|..:::.|.:.|||   :|....:|.:|.|..:.|.
  Rat    71 -NDSGG-----SANLDKSILKVVI---NNKLEQRIIGVINEHKKQNNDRGVISGRLSAKKLQDLY 126

  Fly   137 EHIQ------RDRKRGPVSSTAAEGRDRDR--DW----------------DRDRRRDRDRDRDRD 177
            ..:|      :|.: ..:::|...|.|...  ||                :.:.::.:.|.:.:.
  Rat   127 MALQAFSFKTKDIE-DAMTNTLLHGGDLHSALDWLCLNLSDDALPEGFSQEFEEQQPKSRPKFQS 190

  Fly   178 -------------RDRRQHRERERDRHRSWDRDRGRDRDRDRSMSE---RSVHTPREPGTPGGSS 226
                         :.:||..:.:       .:.:..::..:.:|.|   |......|.....||.
  Rat   191 VQIQATLSPPLQTKTKRQEEDPK-------IKPKKEEKSMEVNMKEWILRYAEQQNEEEKSEGSK 248

  Fly   227 GGISNSSWDDEDGEFGQRKSDWDMPTPR-----------------------RHGNKSGDWSVRSG 268
            |.      :|||      |.|   |..|                       :.|.|.....:
  Rat   249 GS------EDED------KFD---PNQRYLNLAARLLDAKEQAAAFKVEKNKQGQKEAQEKI--- 295

  Fly   269 GSRRNHGRQDDTVRPTP--------AHRYNQWAHGRKRSGATPWGEDPESLDLWE------EEQR 319
               |...|:.:|:...|        :|:.|:    ||::.....||...:.:|:|      ||::
  Rat   296 ---RKFQREMETLEDHPIFNPAIKISHQQNE----RKKAPLATDGESALNFNLFEKPAAATEEEK 353

  Fly   320 RLDREWYNIDEGYDDENNPFGGPNSEYF-----RKREEQLEQKRTKRISAQQRQNNRDNELWE-R 378
            ...:|.::: ..:|.....:.|.:.:.|     ||...:......:::..        ...|: |
  Rat   354 GKKKEPHDV-RNFDYTARSWTGKSPKQFLIDWVRKNLPKSPNPSFEKVPV--------GRYWKCR 409

  Fly   379 NRMLTSGVVTLISVNDDFDEEALERVHL-------------LVHHIIPP-FLDGRIVFT---KQP 426
            .|::.|....|:.......|:.::..||             .||.::|| :.|..:.::   |:.
  Rat   410 VRVVKSEDDVLVVCPTILTEDGMQAQHLGATLALYRLVKGQSVHQLLPPTYRDVWVEWSDEEKKK 474

  Fly   427 EPVVPVKDPTSDMALLARKGSALVRNYREQKERRKAQKK---------HWELSGTKLGNIMGVQR 482
            |.:..::........:|:..|.|.:..:.|::|:..:.|         .||       |::
  Rat   475 EELNKMETNKPRDLFIAKLLSKLKQQQQLQQQRQHPENKTETAEDPEESWE-------NLV---- 528

  Fly   483 PQDEDDMRFDKEKDKAD--------YRKDQKFADHMRDQDTGGKSDFSRKKTISEQRRFLPVFAS 539
             .|||......|...|:        :|:.|....:.|               :.::|:.||||..
  Rat   529 -SDEDLSALSLEPTGAEDLEPVRNLFRRLQSTPKYQR---------------LLKERQQLPVFKH 577

  Fly   540 RQELLNVIRENSVIIIVGETGSGKTTQLTQYLHED------GYSKRGMIGCTQPRRVAAMSVAKR 598
            |..::..::.:.|:::.|||||||:||:..:|.||      |..|..:: ||||||::|:|:|.|
  Rat   578 RASIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNDCGARKCNIV-CTQPRRISAVSLATR 641

  Fly   599 VSDEMDTQLGED-----VGYAIRFEDCTSERTVIKYMTDGILLRESLRDPELDSYSAIIMDEAHE 658
            |.:|:..:.|..     .||.||.|...||.|.:.|.|.|:|||:...|..|...|.:|:||.||
  Rat   642 VCEELGCEGGPGGRNSLCGYQIRMESRASESTRLLYCTTGVLLRKLQEDGLLADVSHVIVDEVHE 706

  Fly   659 RSLSTDVLFGLLREIVARRHDLKLIVTSATMDSSKFATFFGNVPTFTIPGRTFPVDV-------- 715
            ||:.:|.|..:|:||:.:|.||.||:.|||:||.||:|:|.:.|...|.||::||:|
  Rat   707 RSVQSDFLLVILKEILQKRSDLHLILMSATVDSDKFSTYFTHCPILRISGRSYPVEVFHLEDIVE 771

  Fly   716 ----MFSKNT--CEDYVE----------------------------------------SAVKQAL 734
                :..|::  |:.::|                                        |:..|..
  Rat   772 ETGFILEKDSEYCQKFLEEEEEITINVTSKAGGIKKYQECIPVQSGASPELSPFYQKYSSRTQYA 836

  Fly   735 QVHLTPN-----------------------EGDMLIFMPGQEDIEVTCEVL-------EERLAEI 769
            .:::.|:                       ||.:|||:||...|:...::|       .||
  Rat   837 VLYMNPHKINLDLILELLVYLDKSPQFRNIEGAVLIFLPGLAHIQQLYDLLSNDRRFYSER---- 897

  Fly   770 DNAPALSILPIYSQLPSDLQAKIFQKSSDGLRKCVVATNIAETSLTVDGIIYVIDSGYCKLKVYN 834
                 ..::.::|.|.:..||..|.....|:||.|:|||||||.:|:..:::|||:|..|...|:
  Rat   898 -----YQLIALHSVLSTQDQAAAFMLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYH 957

  Fly   835 PRIGMDALQIYPISQANANQRSGRAGRTGPGQAYRLYTQRQYKDELLALTVPEIQRTNLANTVL- 898
            ....|.:|....:|:|:|.||.|||||...|..:||||:.:: :..|..:||||.|..|....|
  Rat   958 ESSQMSSLVETFVSKASALQRQGRAGRVRDGFCFRLYTRERF-EGFLEYSVPEILRVPLEELCLH 1021

  Fly   899 LLK-SLGVVDLLQFHFMDPPPQDNILNSLYQLWILGALDHT-GALTTLGRQMAEFPLDPPQCQML 961
            ::| .||..:......:|||....|.|::..|..:||.:.: ..||.||:.:|..|::....:||
  Rat  1022 IMKCDLGSPEDFLSKALDPPQPQVISNAMNLLRKIGACEPSEPKLTPLGQHLAALPVNVKIGKML 1086

  Fly   962 IVACRMGCSAEVLIIVSMLSVPSIFYRPKGREDEADGVREKFQRPESDHLTYLNVYQQWR----Q 1022
            |.....||...|..:.::::..|.|..|.||:||||..:......:|||||..|.|..|:    :
  Rat  1087 IFGAIFGCLEPVATLAAVMTEKSPFITPIGRKDEADLAKSSLAVADSDHLTIYNAYLGWKKAQQE 1151

  Fly  1023 NNYSS--TWCNEHFIHIKAMRKVREVRQQLKDIMTQQNLS------------------------V 1061
            ..:.|  ::|..:|::..::..:.:|:|:|..::.....|                        |
  Rat  1152 GGFRSEISYCQRNFLNRTSLLTLEDVKQELMKLVRAAGFSSSTSWEGKKGPQALSFQDIALLKAV 1216

  Fly  1062 ISCGIDWDIVRKCICSAYFYQAARLKGIGEYVNLRTGMPC---------HLHPTSALYGLGTTPD 1117
            ::.|: :|.|.|.:|:             :.|::...:.|         .:||:|....| .|..
  Rat  1217 LAAGL-YDSVGKIMCT-------------KSVDVTEKLACMVETAQGKAQVHPSSVNRDL-QTYG 1266

  Fly  1118 YVVYHELIMTAKEYMQCATAV 1138
            :::|.|.:..|:.|::..|.:
  Rat  1267 WLLYQEKVRYARVYLRETTLI 1287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp16	NP_572947.1	HrpA	534..>1148	CDD:441249	213/742 (29%)
Dhx29	NP_001414443.1	None