Protein Alignment Prp16 and dhx29

DIOPT Version :10

• Sequence 1: NP_572947.1
• Gene: Prp16 / 32373
• FlyBaseID: FBgn0026713
• Length: 1222
• Species: Drosophila melanogaster
• Sequence 2: XP_004910409.1
• Gene: dhx29 / 100216168
• XenbaseID: XB-GENE-995260
• Length: 1363
• Species: Xenopus tropicalis
• Alignment Length: 1174
• Identity: 294/1174 - (25%)
• Similarity: 467/1174 - (39%)
• Gaps: 324/1174 - (27%)

  Fly   228 GISNSSWDDEDGEFGQRKSDWDMPTPRR------------------HGNKS---GDWSVR--SGG 269
            |.|....::|     ||......|.|:|                  .|||.   .:|.::  ..|
 Frog   173 GFSQQFVEEE-----QRARAKFQPPPQRPSAANVLGTEKAKEGAAFKGNKELSMKEWILQYAEQG 232

  Fly   270 SRRNHGRQDDTV---RPT-----PAHRYNQWA----HGRKRSGATPWGEDPESLDLWEEEQRRLD 322
            |..:...:.:|.   .||     |..||.:..    ..|.::.||...:|.:.   .:|.|.|:
 Frog   233 SDDDEEEEKETALEKHPTSEKFDPNERYLELTAKLLDARAQAAATKQDKDKQG---QKEAQERI- 293

  Fly   323 REWYNIDEGYDD-----ENNPFGGP--------------------------NSEYFRKREEQLEQ 356
                   .||..     |::|...|                          |...|.|.|...|.
 Frog   294 -------RGYQQEMKSLEDHPLFNPAVKIPEVKSESKQPRPALPPSDEESLNFNLFEKIENAPED 351

  Fly   357 KRTKRISAQQRQNNRDNELWE------------RNRMLTS---------------GVVTLISVND 394
            |..|:.....|..:..:..|.            |.....|               ..|.:|..:|
 Frog   352 KAKKKPPLDIRNFDYTSRSWTGKSPKQFLIDWCRKHYQKSPNPSFEKVPVGKYWKSRVKIIKSHD 416

  Fly   395 D--------FDEEALERVHLL-------------VHHIIPPFLDGRIVFTKQPEPVVPVKDPTSD 438
            |        ..|::::..||.             ||.::||..  |.|:.:..:....|::
 Frog   417 DVMCVCPTIVTEDSMQAQHLAATLALYELTKGQSVHQLLPPTY--RDVWLEWSDAEKQVQE---- 475

  Fly   439 MALLARKGSALVRNYREQKERR-----------KAQKKHWELSGTKLGNIMGVQRPQDED----- 487
                        :|..|..:.|           |.|:...:.||         |.|..||
 Frog   476 ------------QNKMESNKPRDQFITKLLNKLKLQQNQLKSSG---------QNPVTEDPEDSW 519

  Fly   488 -DMRFDKEKDKA--------DYRKDQKFADHMRDQDTGGKSDFSRKKTISEQRRFLPVFASRQEL 543
             ::..|:|:.:.        |....:......||.        .:.|.:...|..|||||.|:.:
 Frog   520 ENLACDEEQIETCPSTAQTDDLEPIRNLLLKSRDS--------IKYKRLLNDREQLPVFAHRKFI 576

  Fly   544 LNVIRENSVIIIVGETGSGKTTQLTQYLHEDGYSKRGMIG-----CTQPRRVAAMSVAKRVSDEM 603
            |..::.:.||::.|||||||:||:.|:|.||....||..|     ||||||::|||:|.||.:|:
 Frog   577 LETLKRHRVIVVAGETGSGKSTQVPQFLLEDLLLNRGSPGKCNIVCTQPRRISAMSLATRVCEEL 641

  Fly   604 DTQLGED-----VGYAIRFEDCTSERTVIKYMTDGILLRESLRDPELDSYSAIIMDEAHERSLST 663
            ....|..     .||.||.|..|.|.|.:.|.|.|||||:...|..|.:.|.||:||.|||::.:
 Frog   642 GCDSGPGGRNSLCGYQIRMESRTGEATRLLYCTTGILLRKLQEDSMLKNISHIIVDEVHERTVQS 706

  Fly   664 DVLFGLLREIVARRHDLKLIVTSATMDSSKFATFFGNVPTFTIPGRTFPVDVMFSKNT------- 721
            |.|..:||||:.:|.||.|::.|||:|..||:::|.:.|...|.||||||:|...::.
 Frog   707 DFLLIILREILHKRSDLHLVLMSATVDCEKFSSYFTHCPIIRISGRTFPVEVFHLEDVVEATGFV 771

  Fly   722 -------CEDYVESAVKQALQV----------------------------------------HLT 739
                   |:.::|...:..|.|                                        ::.
 Frog   772 LEQDSEYCQKFLEDEEEITLSVTGKGGSSTKYQEFIPALSDTGLDLGQRYQRYSSQTRHAVLYMN 836

  Fly   740 PN-----------------------EGDMLIFMPGQEDIEVTCEVLEERLAEIDNAPALSILPIY 781
            ||                       ||.:|||:||..||:...::|... ....:.....::.::
 Frog   837 PNKINLDLILELLVFLDISPQYRNVEGAVLIFLPGLADIQQLYDILSSD-KRFHDRRRYKLIALH 900

  Fly   782 SQLPSDLQAKIFQKSSDGLRKCVVATNIAETSLTVDGIIYVIDSGYCKLKVYNPRIGMDALQIYP 846
            |.|.|..||:.|.....|.||.|:|||||||.:|:..:::|:|:|..|...|:....|.:|....
 Frog   901 SILSSQDQAEAFILPPAGTRKIVLATNIAETGITIPDVVFVVDAGRTKENRYHESSQMSSLVETF 965

  Fly   847 ISQANANQRSGRAGRTGPGQAYRLYTQRQYKDELLALTVPEIQRTNLANTVL-LLK-SLGVVDLL 909
            ||:|:|.||.|||||...|..:||||:.:: :..:..:||||.|..|....| ::| .||..:..
 Frog   966 ISKASALQRQGRAGRVRDGFCFRLYTRERF-EGFMEYSVPEILRVPLEELCLHIMKCDLGSPEDF 1029

  Fly   910 QFHFMDPPPQDNILNSLYQLWILGALD-HTGALTTLGRQMAEFPLDPPQCQMLIVACRMGCSAEV 973
            ....:|||....|.|::..|..:||.: ....||.||:.:|..|::....:|||.....||...|
 Frog  1030 LSKALDPPQLQVISNAMNLLRKIGACELIQPRLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDAV 1094

  Fly   974 LIIVSMLSVPSIFYRPKGREDEADGVREKFQRPESDHLTYLNVYQQW---RQNNYSS--TWCNEH 1033
            ..:.:.::..|.|..|.|.:|.||..:.......|||||....|..|   |.:.|::  ::|.::
 Frog  1095 ATLAATMTEKSPFVTPIGEKDRADLAKSSMAVANSDHLTIFRAYLGWKAIRSDGYAAEMSYCRKN 1159

  Fly  1034 FIHIKAMRKVREVRQQLKDIM---------------TQQNLSVISCGIDWDIVRKCICSAYFYQA 1083
            |::.||:..:.:|:|:|..::               ...|:..:|.  :...:.|.|.:|..|.
 Frog  1160 FLNRKALLTIEDVKQELIRLVRAAGFECPRFVEPNGLSDNMKALSA--EETSLLKAILTAGLYD- 1221

  Fly  1084 ARLKGIGEY-----VNLRTGMPC---------HLHPTSALYGLGTTPDYVVYHELIMTAKEYMQC 1134
                .:|:.     |::...:.|         .:||:|....| .|..:::|.|.|..:|.:::.
 Frog  1222 ----NVGKILFTNSVDITEKLACMVETAQGKAQVHPSSVNRDL-QTYGWLLYQEKIKYSKVFLRE 1281

  Fly  1135 ATAV 1138
            :|.:
 Frog  1282 STLI 1285

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp16	NP_572947.1	HrpA	534..>1148	CDD:441249	219/729 (30%)
dhx29	XP_004910409.1	HrpA	565..>1184	CDD:441249	200/620 (32%)
		OB_NTP_bind	1211..1297	CDD:400182	17/81 (21%)