Protein Alignment Prp16 and dhx32a

DIOPT Version :10

• Sequence 1: NP_572947.1
• Gene: Prp16 / 32373
• FlyBaseID: FBgn0026713
• Length: 1222
• Species: Drosophila melanogaster
• Sequence 2: NP_001189401.3
• Gene: dhx32a / 100006246
• ZFINID: ZDB-GENE-130613-6
• Length: 728
• Species: Danio rerio
• Alignment Length: 765
• Identity: 225/765 - (29%)
• Similarity: 382/765 - (49%)
• Gaps: 90/765 - (11%)

  Fly   468 ELSGTKLGNIMGVQRPQDEDDMRFDKEKDKADYRKDQKFADHMRDQDTGGKSDFSRKKTISEQRR 532
            |||| :||                   |::.|.....:|.|.:......|....||...:.::|:
Zfish     6 ELSG-ELG-------------------KEEEDSENLFEFGDDLELNQFDGLPYSSRYYRLLQERK 50

  Fly   533 FLPVFASRQELLNVIRENSVIIIVGETGSGKTTQLTQYLHE---DGYSKRGMIGCTQPRRVAAMS 594
            .|||:..|.|.:.::..|.::|:.|.|.:||:||:.|:..|   ....:.|::.|:|.:|..|:.
Zfish    51 TLPVWKYRHEFMTLLENNQILIVSGTTKTGKSTQIPQWCAEFCLSAQYQHGVVVCSQIQRRQAVD 115

  Fly   595 VAKRVSDEMDTQLGEDVGYAIRFEDCTSERTVIKYMTDGILLRESLRDPELDSYSAIIMDEAHER 659
            :|.||:||||..:|.::||:|..|.|.|..|:::|.||.|||||.:.||.|:.|..:::|:||||
Zfish   116 LALRVADEMDVNIGHEIGYSIPLETCCSNDTILRYCTDDILLREMMSDPLLEQYGVVLVDQAHER 180

  Fly   660 SLSTDVLFGLLREIVARRHDLKLIVTSATMDSSKFATFFGNVPTFTIPGRTFPVDVMFSKNTCED 724
            ::|||||.|||||::.:|.:|:|:|.||........|.:|:||...:...: ..:|:.|.::..:
Zfish   181 TVSTDVLLGLLREVLLQRPELRLVVLSAPPTPETLLTHYGSVPRLHLEAPS-AGEVIHSSSSSSE 244

  Fly   725 YVESAVKQALQVHLTPNEGDMLIFMPGQEDIEVTCEVLEER-------LAEIDNAPALS----IL 778
            ...||::.||:||.:...||:.:|:..::::...|.::.:.       |.|:...|..|    |.
Zfish   245 SFYSALRLALEVHRSREPGDVAVFLATEQEVVCACNIITKEASRMSVSLGELLAVPMCSGHAGIC 309

  Fly   779 PIYSQLPSDLQAKIFQKSSDGLRKCVVATNIAETSLTVDGIIYVIDSGYCKLKVYNPRIGMDALQ 843
            |..::.| .:..:||          |..:.:.:...:||.|.:|||:|..|..|||||:...:..
Zfish   310 PPVTESP-QMSRRIF----------VSCSQLEDLFWSVDSIAFVIDTGVEKRLVYNPRLRASSEV 363

  Fly   844 IYPISQANANQRSGRAGRTGPGQAYRLYTQRQYKDELLALTVPEIQRTNLANTVLLLKSLGVVDL 908
            |.|||:..|..|....|.|  |:.:.||.:   ..:|.|...|.|..:|:.:|.|.||.:....:
Zfish   364 IRPISKCQAEMRKQLTGST--GKCFCLYPE---DVQLPAEIHPRILESNITSTALFLKRMEAAGV 423

  Fly   909 LQFHFMDPPPQDNILNSLYQLWILGALDHTGALTTLGRQMAEFPLDPPQCQMLIVACRMGCSAEV 973
            ...||::.|..:.::.:|.:|..|.|||:.|.|:.:|..|:|.||:|...:.|:.:|...|::|:
Zfish   424 THCHFINRPDPEGLMQALEELDYLAALDNDGNLSEMGIIMSELPLEPQMAKALLASCEFDCASEM 488

  Fly   974 LIIVSMLSVPSIFYRPK-GREDEADGVREKFQRPESDHLTYLNVYQQWRQNN---YSS--TWCNE 1032
            |.|.:||:.||.|..|. |...|......|||.||.||.|.:|:|..::::.   |.|  .||.:
Zfish   489 LTIAAMLTAPSCFIEPPVGMLTEVMRCHMKFQHPEGDHFTLINIYNTFKRSQREPYFSQEQWCEQ 553

  Fly  1033 HFIHIKAMRKVREVRQQLKDIMTQQNLSVISCGIDWDI----VRKCICSAYFYQAAR-LKGIGEY 1092
            :::...|::....:|.||.|::.:..|.:.........    :::.:.:.||.|.|| :.|.|.|
Zfish   554 YYLCCAALQTADAIRSQLSDVLKRIELPISEPAFGTKTNALNIKRALLAGYFMQMARDVDGSGNY 618

  Fly  1093 VNLRTGMPCHLHPTSALYG-----LGTTPDYVVYHELIMTAKEYMQCATAVDGYWLAELGPMFF- 1151
            ..|........|..|| ||     || .|:::::||..:|... ::..|.:..:...::.|.:|
Zfish   619 FMLLNKHVAQAHRLSA-YGAKAQKLG-LPEWLLFHEYSLTDNS-IRTLTHISPHAFVQMAPQYFF 680

  Fly  1152 -------------SVKESGRSGREKKKQAAEHLKEMEEQMLKAQHEMEER 1188
                         ::.:..|:|..|.|...|...|.:|.      |.:||
Zfish   681 CNLPPSESKEILQNILDRDRTGIPKAKTRPEPKTETQES------EAQER 724

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Prp16	NP_572947.1	HrpA	534..>1148	CDD:441249	199/643 (31%)
dhx32a	NP_001189401.3	HrpA	52..>620	CDD:441249	186/584 (32%)
		DEAD-like_helicase_N	52..227	CDD:475120	72/174 (41%)
		OB_NTP_bind	596..678	CDD:400182	22/84 (26%)