Protein Alignment yl and si:dkey-258f14.3

DIOPT Version :10

• Sequence 1: NP_996433.1
• Gene: yl / 32367
• FlyBaseID: FBgn0004649
• Length: 1984
• Species: Drosophila melanogaster
• Sequence 2: XP_021334056.3
• Gene: si:dkey-258f14.3 / 571152
• ZFINID: ZDB-GENE-050809-43
• Length: 526
• Species: Danio rerio
• Alignment Length: 651
• Identity: 177/651 - (27%)
• Similarity: 257/651 - (39%)
• Gaps: 173/651 - (26%)

  Fly    63 HVAISLLLLVGL-CGGTAAGTPGSADTRCDAGQFQCRDGGCILQAKMCDGRGDCKDSSDELDCDY 126
            |:...|||..|: |.....|.|     :|...||.|.:..|:..:..||...||.|.|||:.|
Zfish    15 HLGAFLLLWTGVSCLPLTEGFP-----KCTVLQFVCANSRCVSLSSRCDAVNDCGDGSDEISC-- 72

  Fly   127 RLCRPPHWFPCAQPHGACLAAELMCNGIDNCPGGEDELNCPVRPGFRFGDTAHRMRSCSKYEFMC 191
                   |                     ||..|                           .|.|
Zfish    73 -------W---------------------NCTNG---------------------------SFHC 82

  Fly   192 QQDRTCIPIDFMCDGRPDCTDKSDEVAGCKQAEITCPGEGHLCANGRCLRRKQWVCDGVDDCGDG 256
            ....:|:....:|||||||.|.:||                                .:|.|...
Zfish    83 VASESCVSSSSVCDGRPDCADGADE--------------------------------QLDTCTSF 115

  Fly   257 SDERGCLNLCEPQKGKFLCRNRETCLTLSEVCDGHSDCSDGSDETDLCHSKPDCDAKKCAL---- 317
            |..:.|      .:.:|.|.|.: |:..|..||..|||.|||||       .|||..:||:
Zfish   116 SQAQPC------ARSEFTCTNGQ-CVPNSWRCDHSSDCKDGSDE-------EDCDHNECAVNNGG 166

  Fly   318 -GAKCHMMPASGAECFCPKGFRLAKFEDKCEDVDECKEQDDLCSQGCENTSGGYRCVCDAGYLLD 381
             ...|..:| .|..|.||||.||.: :..||.||:|.:. |:|.|.|.:::|...|.|..||.|.
Zfish   167 CSHTCIDLP-FGFRCDCPKGMRLVQ-DTHCEVVDQCLDA-DVCDQICVHSNGSVVCDCQDGYQLT 228

  Fly   382 KDNRTCRAVVYGSKEQQPLLLYTTQMTIMGMHLREDNVRNHVYQ--VAGNLSKVIGVAYDGSH-- 442
            .....|||.  |....   :..:||..|..|.|.....||...:  ..|.:|.:      .:|
Zfish   229 AGTGQCRAT--GGLAH---VAVSTQEGIKMMDLSGSEERNITDKRLSPGPVSAL------NAHNT 282

  Fly   443 IYWTNIQNEAESIVKANGDGSNAEILLTSGLDAPE--------------DLAVDWLTQNIYFSDN 493
            :||::.:|               :|:....||:.:              .|||||:.:::|:...
Zfish   283 LYWSSPEN---------------DIIYRMSLDSGDHRPAVWLKASKGIVGLAVDWIHESLYWIST 332

  Fly   494 IMR--HIAVCSNDGLNCAVLVTQDVHQPRSLAVWPQKGLMFWTDWGEKPMIGRASMDGSRSRPIV 556
            ..|  |:|...|....   |:...:.:|.::||.|..|.:||.:.||...|.|..:||.....:|
Zfish   333 STRALHMASLKNTKQR---LLISGLSKPTAVAVQPLLGYVFWAEGGESARIERVGLDGESRFALV 394

  Fly   557 SDNIEWPNGIALDMHQQRIYWVDAKLGSVQTVRPDGTGRRTVLD--GMLKHPYGLAIFEDQLYWS 619
            ...:..|..|:||:.:..:||.|:.|.|:..|..||..|:||::  |.|..|:||||||.::|||
Zfish   395 VSFVRNPVAISLDIPRGLLYWADSGLRSISRVLFDGQYRKTVVESNGYLDQPFGLAIFESRVYWS 459

  Fly   620 DWATKSVHACHKFSGKDHRILAK--DRTIYAVHIYHPAKQPNSPHGC---ENATCSHLCLLAEPE 679
            |..|.|:.:..|.:|...|:..:  ..:...:.|.||..||.:...|   .....|.:.:|..||
Zfish   460 DQLTNSICSADKHNGTMLRVPQRLGSASPAGLVILHPLLQPAAALSCLYSLTGAVSLIFILVIPE 524

  Fly   680 I 680
            |
Zfish   525 I 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
yl	NP_996433.1	LDLa	90..124	CDD:238060	13/33 (39%)
		LDLa	131..166	CDD:238060	4/34 (12%)
		LDLa	184..216	CDD:238060	11/31 (35%)
		LDLa	227..262	CDD:238060	3/34 (9%)
		LDLa	271..302	CDD:238060	15/30 (50%)
		FXa_inhibition	352..387	CDD:464251	11/34 (32%)
		Ldl_recept_b	442..483	CDD:459654	10/56 (18%)
		LY	466..508	CDD:214531	13/57 (23%)
		Ldl_recept_b	529..569	CDD:459654	12/39 (31%)
		LY	553..595	CDD:214531	13/41 (32%)
		LY	596..637	CDD:214531	19/42 (45%)
		FXa_inhibition	669..700	CDD:464251	5/12 (42%)
		LY	774..815	CDD:214531
		LDLa	1032..1062	CDD:238060
		LDLa	1074..1109	CDD:238060
		LDLa	1118..1152	CDD:238060
		LDLa	1157..1189	CDD:197566
		LDLa	1198..1232	CDD:238060
		LDLa	1243..1279	CDD:238060
		LDLa	1283..1318	CDD:238060
		LDLa	1340..1371	CDD:197566
		FXa_inhibition	1388..1416	CDD:464251
		EGF_CA	1418..1452	CDD:214542
si:dkey-258f14.3	XP_021334056.3	None