DRSC/TRiP Functional Genomics Resources

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Protein Alignment yl and Ldlrad3

DIOPT Version :10

Sequence 1:NP_996433.1 Gene:yl / 32367 FlyBaseID:FBgn0004649 Length:1984 Species:Drosophila melanogaster
Sequence 2:NP_849217.2 Gene:Ldlrad3 / 241576 MGIID:2138856 Length:345 Species:Mus musculus


Alignment Length:132 Identity:55/132 - (41%)
Similarity:69/132 - (52%) Gaps:9/132 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly  1033 FRCHSGECLTMNHRCNGRRDCVDNSDEMNCDEEHRRKPKVLCSPNQFACHSGEQCVDKERRCDNR 1097
            |.|.:|.|:....:|:|..||.|.|||..|.     |.|..|.|..|.|.||..|:....||:..
Mouse    35 FMCSNGRCIPGAWQCDGLPDCFDKSDEKECP-----KAKSKCGPTFFPCASGIHCIIGRFRCNGF 94

  Fly  1098 KDCHDHSDEQHCEKFDKSKKCHVHQHGCDNGKCVDSSLVCDGTNDCGDNSDELLCEATSRCEPGM 1162
            :||.|.|||::|..  ....|...::.|.||.|:|.|.:|||.|:|.|||||..||  |..|||.
Mouse    95 EDCPDGSDEENCTA--NPLLCSTARYHCRNGLCIDKSFICDGQNNCQDNSDEESCE--SSLEPGS 155

  Fly  1163 FQ 1164
            .|
Mouse   156 GQ 157

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ylNP_996433.1 LDLa 90..124 CDD:238060
LDLa 131..166 CDD:238060
LDLa 184..216 CDD:238060
LDLa 227..262 CDD:238060
LDLa 271..302 CDD:238060
FXa_inhibition 352..387 CDD:464251
Ldl_recept_b 442..483 CDD:459654
LY 466..508 CDD:214531
Ldl_recept_b 529..569 CDD:459654
LY 553..595 CDD:214531
LY 596..637 CDD:214531
FXa_inhibition 669..700 CDD:464251
LY 774..815 CDD:214531
LDLa 1032..1062 CDD:238060 12/28 (43%)
LDLa 1074..1109 CDD:238060 15/34 (44%)
LDLa 1118..1152 CDD:238060 17/33 (52%)
LDLa 1157..1189 CDD:197566 4/8 (50%)
LDLa 1198..1232 CDD:238060
LDLa 1243..1279 CDD:238060
LDLa 1283..1318 CDD:238060
LDLa 1340..1371 CDD:197566
FXa_inhibition 1388..1416 CDD:464251
EGF_CA 1418..1452 CDD:214542
Ldlrad3NP_849217.2 LDLa 32..64 CDD:238060 12/28 (43%)
LDLa 71..106 CDD:238060 15/34 (44%)
LDLa 113..147 CDD:238060 17/33 (52%)
Involved in ITCH interaction. /evidence=ECO:0000250|UniProtKB:Q86YD5 256..259
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 270..345
Involved in ITCH interaction. /evidence=ECO:0000250|UniProtKB:Q86YD5 275..278
Blue background indicates that the domain is not in the aligned region.

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