| Sequence 1: | NP_996433.1 | Gene: | yl / 32367 | FlyBaseID: | FBgn0004649 | Length: | 1984 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_038731.2 | Gene: | Vldlr / 22359 | MGIID: | 98935 | Length: | 873 | Species: | Mus musculus |
| Alignment Length: | 788 | Identity: | 241/788 - (30%) |
|---|---|---|---|
| Similarity: | 349/788 - (44%) | Gaps: | 200/788 - (25%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 67 SLLLLVGLC------GGTAAGTPGSADTRCDAGQFQCRDGGCILQAKMCDGRGDCKDSSDELDC- 124
Fly 125 -------DY---------------------------------RLCR--------------PPHW- 134
Fly 135 -------------------------FPCAQPHGACLAAELMCNGIDNCPGGEDELNCPVRPGFRF 174
Fly 175 GDTAHRMRSCSKYEFMCQQDRTCIPIDFMCDGRPDCTDKSDE-VAGCKQAEI---TCPGEGHLCA 235
Fly 236 NGRCLRRKQWVCDGVDDCGDGSDERGC-LNLCEPQK----------------------------- 270
Fly 271 ----------GKFLCRNRETCLTLSEVCDGHSDCSDGSDETDLCHSKPDCDAKKCAL--GAKCHM 323
Fly 324 MP--ASGAECFCPKGFRLAKFEDKCEDVDECKEQDDLCSQGCENTSGGYRCVCDAGYLLDKDNRT 386
Fly 387 CRAVVYGSKEQQPLLLYTTQMTIMGMHLREDNVRNHVYQVAGNLSKVIGVAYD--GSHIYWTNIQ 449
Fly 450 NEAESIVKAN-GDGSNAEILLTSGLDAPEDLAVDWLTQNIYFSDNIMRHIAVCSNDGLNCAVLVT 513
Fly 514 QDVHQPRSLAVWPQKGLMFWTDWGEKPMIGRASMDGSRSRPIVSDNIEWPNGIALDMHQQRIYWV 578
Fly 579 DAKLGSVQTVRPDGTGRRTVLDGM--LKHPYGLAIFEDQLYWSDWATKSVHACHKFSGKDHRIL- 640
Fly 641 -----AKDRTIYAVHIYHPAKQPNSPHGC----ENATCSHLCLLAEPEIGGHS----CACPDGMR 692
Fly 693 LAPDHRRC 700 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| yl | NP_996433.1 | LDLa | 90..124 | CDD:238060 | 18/33 (55%) |
| LDLa | 131..166 | CDD:238060 | 15/60 (25%) | ||
| LDLa | 184..216 | CDD:238060 | 13/31 (42%) | ||
| LDLa | 227..262 | CDD:238060 | 17/34 (50%) | ||
| LDLa | 271..302 | CDD:238060 | 17/30 (57%) | ||
| FXa_inhibition | 352..387 | CDD:291342 | 14/34 (41%) | ||
| Ldl_recept_b | 442..482 | CDD:278487 | 7/40 (18%) | ||
| LY | 466..508 | CDD:214531 | 12/41 (29%) | ||
| Ldl_recept_b | 529..569 | CDD:278487 | 19/39 (49%) | ||
| LY | 553..595 | CDD:214531 | 19/41 (46%) | ||
| LY | 596..637 | CDD:214531 | 18/42 (43%) | ||
| FXa_inhibition | 669..700 | CDD:291342 | 15/34 (44%) | ||
| LY | 774..815 | CDD:214531 | |||
| LDLa | 1032..1062 | CDD:238060 | |||
| LDLa | 1074..1109 | CDD:238060 | |||
| LDLa | 1118..1152 | CDD:238060 | |||
| LDLa | 1157..1189 | CDD:197566 | |||
| LDLa | 1198..1232 | CDD:238060 | |||
| LDLa | 1243..1279 | CDD:238060 | |||
| LDLa | 1283..1318 | CDD:238060 | |||
| LDLa | 1340..1371 | CDD:197566 | |||
| FXa_inhibition | 1388..1416 | CDD:291342 | |||
| EGF_CA | 1418..1452 | CDD:214542 | |||
| Vldlr | NP_038731.2 | LDLa | 33..67 | CDD:238060 | 18/33 (55%) |
| LDLa | 71..103 | CDD:197566 | 1/31 (3%) | ||
| Ldl_recept_a | 111..149 | CDD:365841 | 5/37 (14%) | ||
| Ldl_recept_a | 153..188 | CDD:365841 | 13/36 (36%) | ||
| Ldl_recept_a | 192..224 | CDD:365841 | 13/32 (41%) | ||
| Ldl_recept_a | 237..273 | CDD:365841 | 17/36 (47%) | ||
| Ldl_recept_a | 276..312 | CDD:365841 | 2/35 (6%) | ||
| Ldl_recept_a | 320..350 | CDD:365841 | 15/30 (50%) | ||
| FXa_inhibition | 360..394 | CDD:373209 | 10/34 (29%) | ||
| EGF_CA | 396..426 | CDD:214542 | 15/30 (50%) | ||
| LDL-receptor class B 1 | 439..480 | 9/44 (20%) | |||
| LY | 461..499 | CDD:214531 | 7/39 (18%) | ||
| LDL-receptor class B 2 | 481..524 | 10/44 (23%) | |||
| Ldl_recept_b | 481..521 | CDD:278487 | 7/41 (17%) | ||
| LY | 508..547 | CDD:214531 | 12/38 (32%) | ||
| LDL-receptor class B 3 | 525..567 | 14/41 (34%) | |||
| LDL-receptor class B 4 | 568..611 | 21/42 (50%) | |||
| Ldl_recept_b | 568..608 | CDD:278487 | 19/39 (49%) | ||
| LY | 592..634 | CDD:214531 | 19/41 (46%) | ||
| LDL-receptor class B 5 | 612..654 | 17/41 (41%) | |||
| LDL-receptor class B 6 | 655..697 | 13/46 (28%) | |||
| Ldl_recept_b | 655..694 | CDD:278487 | 11/43 (26%) | ||
| FXa_inhibition | 711..749 | CDD:373209 | 17/38 (45%) | ||
| Clustered O-linked oligosaccharides | 751..790 | ||||
| Endocytosis signal. /evidence=ECO:0000255 | 832..837 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG1215 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||