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Protein Alignment yl and Ldlr

DIOPT Version :9

Sequence 1:	NP_996433.1	Gene:	yl / 32367	FlyBaseID:	FBgn0004649	Length:	1984	Species:	Drosophila melanogaster
Sequence 2:	NP_034830.2	Gene:	Ldlr / 16835	MGIID:	96765	Length:	862	Species:	Mus musculus

Alignment Length:	781	Identity:	258/781 - (33%)
Similarity:	387/781 - (49%)	Gaps:	111/781 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 GSADTRCDAGQFQCRDGGCILQAKMCDGRGDCKDSSDELDCDYRLCRPPHWFPCAQPHGACLAAE 148
            |.....|....|:|:||.||....:|||..||.|.|||..|....|.|.| |.|..  ..|:.:.
Mouse   103 GCPPKTCSQDDFRCQDGKCISPQFVCDGDRDCLDGSDEAHCQATTCGPAH-FRCNS--SICIPSL 164

  Fly   149 LMCNGIDNCPGGEDE--LNCPVRPGFRFGDTAHRMRS--CSKYEFMCQQDRTCIPIDFMCDGRPD 209
            ..|:|..:|..|.||  .||..|      |||.:..|  ||..||.|.... ||...::|||..|
Mouse   165 WACDGDVDCVDGSDEWPQNCQGR------DTASKGVSSPCSSLEFHCGSSE-CIHRSWVCDGEAD 222

  Fly   210 CTDKSDEVAGCKQAEITCPGEGHLCANGRCLRRKQWVCDGVDDCGDGSDERGCLNL--CEPQKGK 272
            |.||||| ..|  |..||..:...||:|.|:...: .||...||.|.|||.||:|:  |: ...|
Mouse   223 CKDKSDE-EHC--AVATCRPDEFQCADGSCIHGSR-QCDREHDCKDMSDELGCVNVTQCD-GPNK 282

  Fly   273 FLCRNRETCLTLSEVCDGHSDCSDGSDETDLCHSKP--DCDAKKCA--LGAKCHMMP--ASGAEC 331
            |.|.:.| |::|.:|||...||.|.|||       |  :|...:|.  .|...|:..  ..|:||
Mouse   283 FKCHSGE-CISLDKVCDSARDCQDWSDE-------PIKECKTNECLDNNGGCSHICKDLKIGSEC 339

  Fly   332 FCPKGFRLAKFEDKCEDVDECKEQDDLCSQGCENTSGGYRCVCDAGYLLDKDNRTCRAVVYGSKE 396
            .||.||||.... :|||:|||:| .|.|||.|.|..|.|:|.|.||:.:|...|.|:||  ||
Mouse   340 LCPSGFRLVDLH-RCEDIDECQE-PDTCSQLCVNLEGSYKCECQAGFHMDPHTRVCKAV--GS-- 398

  Fly   397 QQPLLLYTTQMTIMGMHLREDNVRNHVYQVAGNLSKVIGVAYD--GSHIYWTNI-QNEAESIVKA 458
             ...||:|.:..:..|.|.    |:....:..||..|:.:..:  .:.|||::: |.:..|.:..
Mouse   399 -IGYLLFTNRHEVRKMTLD----RSEYTSLLPNLKNVVALDTEVTNNRIYWSDLSQKKIYSALMD 458

  Fly   459 NGDGSNAEILLTSGLDAPEDLAVDWLTQNIYFSDNIMRHIAVCSNDGLNCAVLVTQDVHQPRSLA 523
            .....:.:.:::..|.||:.|||||:.:|||::|::...::|....|:....|..:...:||::.
Mouse   459 QAPNLSYDTIISEDLHAPDGLAVDWIHRNIYWTDSVPGSVSVADTKGVKRRTLFQEAGSRPRAIV 523

  Fly   524 VWPQKGLMFWTDWGEKPMIGRASMDGSRSRPIVSDNIEWPNGIALDMHQQRIYWVDAKLGSVQTV 588
            |.|..|.|:|||||....|.:..::|.....:|::||:|||||.||:...|:||||:||.|:.::
Mouse   524 VDPVHGFMYWTDWGTPAKIKKGGLNGVDIHSLVTENIQWPNGITLDLSSGRLYWVDSKLHSISSI 588

  Fly   589 RPDGTGRRTVL--DGMLKHPYGLAIFEDQLYWSDWATKSVHACHKFSGKDHRILAKD-RTIYAVH 650
            ..:|..|:|:|  :..|.||:.|||:||::||:|...:::.:.::.:|.|..::|:: .:...:.
Mouse   589 DVNGGNRKTILEDENRLAHPFSLAIYEDKVYWTDVINEAIFSANRLTGSDVNLVAENLLSPEDIV 653

  Fly   651 IYHPAKQPNSPHGCE------NATCSHLCLLAEPEIGGHS----CACPDGMRLAPDHRRCMLMEK 705
            ::|...||...:.||      |..|.:|||.| |:||.||    |||||||.||.|.|.|:...
Mouse   654 LFHKVTQPRGVNWCETTALLPNGGCQYLCLPA-PQIGPHSPKFTCACPDGMLLAKDMRSCLTEV- 716

  Fly   706 RQRLFIGLGQVLLEIEHTAFGRHQVSKSYTLP-----------------------CLINEMVYNR 747
                     ..:|..:.|:..|..|:.|.|.|                       .:.:..|.::
Mouse   717 ---------DTVLTTQGTSAVRPVVTASATRPPKHSEDLSAPSTPRQPVDTPGLSTVASVTVSHQ 772

  Fly   748 INGSLIIADNDQ-----RLILEFQPESHES-----NVLVRSN--LGNVSALAFDHLSRNLYWADT 800
            :.|.:....|::     |.:..|.|.:..:     .||:..|  |.|::::.||:   .:|...|
Mouse   773 VQGDMAGRGNEEQPHGMRFLSIFFPIALVALLVLGAVLLWRNWRLKNINSINFDN---PVYQKTT 834

  Fly   801 E 801
            |
Mouse   835 E 835

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.