DRSC/TRiP Functional Genomics Resources

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Protein Alignment yl and LOC100536757

DIOPT Version :10

Sequence 1:NP_996433.1 Gene:yl / 32367 FlyBaseID:FBgn0004649 Length:1984 Species:Drosophila melanogaster
Sequence 2:XP_021334054.3 Gene:LOC100536757 / 100536757 -ID:- Length:600 Species:Danio rerio


Alignment Length:749 Identity:193/749 - (25%)
Similarity:287/749 - (38%) Gaps:205/749 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    63 HVAISLLLLVGL-CGGTAAGTPGSADTRCDAGQFQCRDGGCILQAKMCDGRGDCKDSSDELDCDY 126
            |:...|||..|: |.....|.|     :|...||.|.:..|:..:..||...||.|.|||:.|  
Zfish    15 HLGAFLLLWTGVSCLPLTEGFP-----KCTVLQFVCANSRCVSLSSRCDAVNDCGDGSDEISC-- 72

  Fly   127 RLCRPPHWFPCAQPHGACLAAELMCNGIDNCPGGEDELNCPVRPGFRFGDTAHRMRSCSKYEFMC 191
                   |                     ||..|                           .|.|
Zfish    73 -------W---------------------NCTNG---------------------------SFHC 82

  Fly   192 QQDRTCIPIDFMCDGRPDCTDKSDEVAGCKQAEITCPGEGHLCANGRCLRRKQWVCDGVDDCGDG 256
            ....:|:....:|||||||.|.:||                                .:|.|...
Zfish    83 VASESCVSSSSVCDGRPDCADGADE--------------------------------QLDTCTSF 115

  Fly   257 SDERGCLNLCEPQKGKFLCRNRETCLTLSEVCDGHSDCSDGSDETDLCHSKPDCDAKKCAL---- 317
            |..:.|      .:.:|.|.|.: |:..|..||..|||.|||||       .|||..:||:    
Zfish   116 SQAQPC------ARSEFTCTNGQ-CVPNSWRCDHSSDCKDGSDE-------EDCDHNECAVNNGG 166

  Fly   318 -GAKCHMMPASGAECFCPKGFRLAKFEDKCEDVDECKEQDDLCSQGCENTSGGYRCVCDAGYLLD 381
             ...|..:| .|..|.||||.||.: :..||.||:|.:. |:|.|.|.:::|...|.|..||.|.
Zfish   167 CSHTCIDLP-FGFRCDCPKGMRLVQ-DTHCEVVDQCLDA-DVCDQICVHSNGSVVCDCQDGYQLT 228

  Fly   382 KDNRTCRAVVYGSKEQQPLLLYTTQMTIMGMHLREDNVRNHVYQ--VAGNLSKVIGVAYDGSH-- 442
            .....|||.  |....   :..:||..|..|.|.....||...:  ..|.:|.:      .:|  
Zfish   229 AGTGQCRAT--GGLAH---VAVSTQEGIKMMDLSGSEERNITDKRLSPGPVSAL------NAHNT 282

  Fly   443 IYWTNIQNEAESIVKANGDGSNAEILLTSGLDAPE--------------DLAVDWLTQNIYFSDN 493
            :||::.:|               :|:....||:.:              .|||||:.:::|:...
Zfish   283 LYWSSPEN---------------DIIYRMSLDSGDHRPAVWLKASKGIVGLAVDWIHESLYWIST 332

  Fly   494 IMR--HIAVCSNDGLNCAVLVTQDVHQPRSLAVWPQKGLMFWTDWGEKPMIGRASMDGSRSRPIV 556
            ..|  |:|...|....   |:...:.:|.::||.|..|.:||.:.||...|.|..:||.....:|
Zfish   333 STRALHMASLKNTKQR---LLISGLSKPTAVAVQPLLGYVFWAEGGESARIERVGLDGESRFALV 394

  Fly   557 SDNIEWPNGIALDMHQQRIYWVDAKLGSVQTVRPDGTGRRTVLD--GMLKHPYGLAIFEDQLYWS 619
            ...:..|..|:||:.:..:||.|:.|.|:..|..||..|:||::  |.|..|:||||||.::|||
Zfish   395 VSFVRNPVAISLDIPRGLLYWADSGLRSISRVLFDGQYRKTVVESNGYLDQPFGLAIFESRVYWS 459

  Fly   620 DWATKSVHACHKFSGKDHRILAK--DRTIYAVHIYHPAKQPNSPHGCENATCSHLCLLAEPEIGG 682
            |..|.|:.:..|.:|...|:..:  ..:...:.|.||..||...            :|:..||..
Zfish   460 DQLTNSICSADKHNGTMLRVPQRLGSASPAGLVILHPLLQPADK------------VLSPSEIKT 512

  Fly   683 HSCACPDGMRLAPDHRRCMLMEKRQRLFIGLGQVLLEIEHTAFG------RHQVSKSYTLPCLIN 741
            .|     ...|.|...:..|.:.:..|.:.|..|:|.:  ..||      |.::....::..|  
Zfish   513 SS-----NKELLPSETKTALPDSQFTLMLTLIAVILSV--LLFGLVLWWQRSELCAHRSVSLL-- 568

  Fly   742 EMVYNRINGSLIIADNDQRLILEFQPESHESNVL 775
                    |.:.:.::...|:|...|..||...|
Zfish   569 --------GDVTLKESQDPLLLSSLPAVHEHQTL 594

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ylNP_996433.1 LDLa 90..124 CDD:238060 13/33 (39%)
LDLa 131..166 CDD:238060 4/34 (12%)
LDLa 184..216 CDD:238060 11/31 (35%)
LDLa 227..262 CDD:238060 3/34 (9%)
LDLa 271..302 CDD:238060 15/30 (50%)
FXa_inhibition 352..387 CDD:464251 11/34 (32%)
Ldl_recept_b 442..483 CDD:459654 10/56 (18%)
LY 466..508 CDD:214531 13/57 (23%)
Ldl_recept_b 529..569 CDD:459654 12/39 (31%)
LY 553..595 CDD:214531 13/41 (32%)
LY 596..637 CDD:214531 19/42 (45%)
FXa_inhibition 669..700 CDD:464251 6/30 (20%)
LY 774..815 CDD:214531 1/2 (50%)
LDLa 1032..1062 CDD:238060
LDLa 1074..1109 CDD:238060
LDLa 1118..1152 CDD:238060
LDLa 1157..1189 CDD:197566
LDLa 1198..1232 CDD:238060
LDLa 1243..1279 CDD:238060
LDLa 1283..1318 CDD:238060
LDLa 1340..1371 CDD:197566
FXa_inhibition 1388..1416 CDD:464251
EGF_CA 1418..1452 CDD:214542
LOC100536757XP_021334054.3 None
Blue background indicates that the domain is not in the aligned region.

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