DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11584 and POU2AF1

DIOPT Version :9

Sequence 1:	NP_572941.1	Gene:	CG11584 / 32363	FlyBaseID:	FBgn0030541	Length:	662	Species:	Drosophila melanogaster
Sequence 2:	XP_005271650.1	Gene:	POU2AF1 / 5450	HGNCID:	9211	Length:	303	Species:	Homo sapiens

Alignment Length:	335	Identity:	90/335 - (26%)
Similarity:	122/335 - (36%)	Gaps:	88/335 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 LQQHIQSQIHPQVESIQASVPLASFTIQSSGQQQYQSAPAPAPAPVSIPAPAPVVNSAPAP--AP 110
            ||.|.:.  ||      .|..|:...:|:|........|.......|..:||..:..|.||  ||
Human     4 LQSHYEK--HP------PSYLLSWSQLQNSLAAGCGHVPGSQETRGSCGSPATSIGRATAPEQAP 60

  Fly   111 AP------VEVQQPAPQVIYEAPKPVIATQTAAKNAYLPPAPVQQFVPAPEPVVANIAPQQETIT 169
            ||      |.|::|..:::..  |...|:..||              |||..||   .|.|...|
Human    61 APARPYQGVRVKEPVKELLRR--KRGHASSGAA--------------PAPTAVV---LPHQPLAT 106

  Fly   170 TTYNAPAAAPVPAPAPIAIPVPAVQEQHQVIQQTYSVPAPAP----AVQQSYSAPAPAPVVQQTY 230
            .|...|:...:..      .|.||.|:..:.....|.|.||.    |....|:...|...|...|
Human   107 YTTVGPSCLDMEG------SVSAVTEEAALCAGWLSQPTPATLQPLAPWTPYTEYVPHEAVSCPY 165

  Fly   231 SAP---APVVQEQTYTAAAPVQAVQQLTYSAPAPVTQEQYYSAPASVVQQTSSAPAPAPAPVQEQ 292
            ||.   .||.  .:||...|...   |||::|..:|         :|..::|:.||..| |::..
Human   166 SADMYVQPVC--PSYTVVGPSSV---LTYASPPLIT---------NVTTRSSATPAVGP-PLEGP 215

  Fly   293 FYSAPAPAIQQTYSAPAPAPVVQQTYSAPAPAPQQTYSAPAPAVQEQTQVVQSYSAPAPAPVAQQ 357
            .:.||.     || .|.|.|:      :..|.....|..||||:            |.|..| |.
Human   216 EHQAPL-----TY-FPWPQPL------STLPTSTLQYQPPAPAL------------PGPQFV-QL 255

  Fly   358 TYSYPAPVVQ 367
            ..|.|.||:|
Human   256 PISIPEPVLQ 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11584	NP_572941.1	rne	<209..408	CDD:236766	47/166 (28%)
		rne	<329..539	CDD:236766	14/39 (36%)
		TFIIA	475..>635	CDD:281188
POU2AF1	XP_005271650.1	PD-C2-AF1	54..302	CDD:286403	76/277 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15363
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100