Protein Alignment HOXD10 and Antp

DIOPT Version :10

• Sequence 1: NP_002139.2
• Gene: HOXD10 / 3236
• HGNCID: 5133
• Length: 340
• Species: Homo sapiens
• Sequence 2: NP_996167.1
• Gene: Antp / 40835
• FlyBaseID: FBgn0260642
• Length: 378
• Species: Drosophila melanogaster
• Alignment Length: 338
• Identity: 91/338 - (26%)
• Similarity: 141/338 - (41%)
• Gaps: 100/338 - (29%)

Human    34 MYMPP--PSADMGTYGMQTCGLLPSLAKREVNHQNMGMNVHPYIPQVDSWTDPNRSCRIEQPVTQ 96
            :|..|  ||:.:|       |::|   :.:.|.| :|      :||.........|...:|...|
  Fly    82 VYSRPDSPSSQVG-------GVMP---QAQTNGQ-LG------VPQQQQQQQQQPSQNQQQQQAQ 129

Human    97 QVPTCSFTTNIKEESNCCMYSDKRNKLISAEVPSYQRLVPESCPVENPEVPVPGYFRLSQTYATG 161
            |.|                      :.:..::|...:.|..  |.:..:.||        .||:.
  Fly   130 QAP----------------------QQLQQQLPQVTQQVTH--PQQQQQQPV--------VYASC 162

Human   162 KTQEYNNSPEGSSTVMLQLNPRGAAKP---QLSA----AQLQMEKKMNEPVSGQEPT-----KVS 214
            |.|        ::...|.:.|.|.:.|   |:|.    ||:.:...|..|.:....|     .|:
  Fly   163 KLQ--------AAVGGLGMVPEGGSPPLVDQMSGHHMNAQMTLPHHMGHPQAQLGYTDVGVPDVT 219

Human   215 QVESPEAKGGLPEERSCLAEVSV----------SSPEV-QEKESKEEIKSDTPTSN--------- 259
            :|.......|:.:::|.:..|..          ..|:: |....:....|..|.|.
  Fly   220 EVHQNHHNMGMYQQQSGVPPVGAPPQGMMHQGQGPPQMHQGHPGQHTPPSQNPNSQSSGMPSPLY 284

Human   260 -WLTAKSG----RKK-RCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRR 318
             |:.::.|    ||: |..||::|||||||||.||.||||.||:||:.::.||:||:||||||||
  Fly   285 PWMRSQFGKCQERKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWFQNRR 349

Human   319 MKLKKMSRENRIR 331
            ||.||   ||:.:
  Fly   350 MKWKK---ENKTK 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXD10	NP_002139.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	200..268		15/97 (15%)
		Homeodomain	267..323	CDD:459649	38/56 (68%)
Antp	NP_996167.1	KLF1_2_4_N	<161..306	CDD:425360	29/152 (19%)
		Homeodomain	298..354	CDD:459649	37/55 (67%)