Protein Alignment HOXD10 and Dfd

DIOPT Version :10

• Sequence 1: NP_002139.2
• Gene: HOXD10 / 3236
• HGNCID: 5133
• Length: 340
• Species: Homo sapiens
• Sequence 2: NP_477201.1
• Gene: Dfd / 40832
• FlyBaseID: FBgn0000439
• Length: 586
• Species: Drosophila melanogaster
• Alignment Length: 228
• Identity: 63/228 - (27%)
• Similarity: 101/228 - (44%)
• Gaps: 62/228 - (27%)

Human   159 ATGKTQEYNNSPEGSSTVMLQLNPRGAAKPQLSAAQLQ-----MEKKMNEPV------------- 205
            :.|.|....:||. |..:.|.|.......|..:|..||     :||::.|.|
  Fly   224 SVGSTHSQGHSPH-SQMMDLPLQCSSTEPPTNTALGLQELGLKLEKRIEEAVPAGQQLQELGMRL 287

Human   206 ----SGQEPTKVSQVE------SPEAKGGLPEERSCLAEVSVSSPEVQEKESKEEIKSDTPTSN- 259
                .|.|...:|:.:      ||:..|.           :.:..::.:.:|.|::.::|....
  Fly   288 RCDDMGSENDDMSEEDRLMLDRSPDELGS-----------NDNDDDLGDSDSDEDLMAETTDGER 341

Human   260 ----WL--------------TAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLT 306
                |:              .....:::|..||:||.|||||||.:|.||||.||:||:.::.|:
  Fly   342 IIYPWMKKIHVAGVANGSYQPGMEPKRQRTAYTRHQILELEKEFHYNRYLTRRRRIEIAHTLVLS 406

Human   307 DRQVKIWFQNRRMKLK---KMSRENRIRELTAN 336
            :||:||||||||||.|   |:.....:|:.|.:
  Fly   407 ERQIKIWFQNRRMKWKKDNKLPNTKNVRKKTVD 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HOXD10	NP_002139.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	200..268		12/109 (11%)
		Homeodomain	267..323	CDD:459649	35/58 (60%)
Dfd	NP_477201.1	Homeodomain	367..423	CDD:459649	34/55 (62%)