DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mamo and mod(mdg4)

DIOPT Version :9

Sequence 1:	NP_572932.2	Gene:	mamo / 32353	FlyBaseID:	FBgn0267033	Length:	1553	Species:	Drosophila melanogaster
Sequence 2:	NP_788698.1	Gene:	mod(mdg4) / 49228	FlyBaseID:	FBgn0002781	Length:	610	Species:	Drosophila melanogaster

Alignment Length:	473	Identity:	128/473 - (27%)
Similarity:	194/473 - (41%)	Gaps:	112/473 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 EHYCLRWNNYQSNLLGVFSQLLQDGSLVDVTLVCSEGTSIRAHKVVLSACSSYFQSLFLEHPEG- 67
            |.:.|.|||:.:||...|.:.|..|.||||:| .:||..::||::|||.||.:|:.:|.:.|..
  Fly     5 EQFSLCWNNFNTNLSAGFHESLCRGDLVDVSL-AAEGQIVKAHRLVLSVCSPFFRKMFTQMPSNT 68

  Fly    68 HLIVILKDVRFAELQTLVEFMYKGEVNVQYCQLSALLKTAESLKVKGLAEMTNQNTTLREPEREP 132
            |.||.|.:|..:.|:.|::|||.|||||:...|.|.:.|||||::|||.:    |....:|.:|.
  Fly    69 HAIVFLNNVSHSALKDLIQFMYCGEVNVKQDALPAFISTAESLQIKGLTD----NDPAPQPPQES 129

  Fly   133 -------------------DRLRPQGGGG------SGGSAHKAADSPAAALDATAATQAATATAT 172
                               .|.:|:....      ..|...:...:....:..|||.||......
  Fly   130 SPPPAAPHVQQQQIPAQRVQRQQPRASARYKIETVDDGLGDEKQSTTQIVIQTTAAPQATIVQQQ 194

  Fly   173 ATAAAA---------TSTSTSATSAAATAAATAATSASTTATAAAGSSNTTTTTAATT----TAT 224
            ....||         |.|:|:|| ..:|...:|..|:.|.|:::||...:.|:|:|..    .:|
  Fly   195 QPQQAAQQIQSQQLQTGTTTTAT-LVSTNKRSAQRSSLTPASSSAGVKRSKTSTSANVMDPLDST 258

  Fly   225 CATAATSTA-----ATSSSSSVTSAAAAAAAAASASGVAHSEEATSSSSSTGGQKREASDRSSPT 284
            ..|.||:||     ..:..:||.|||.|
  Fly   259 TETGATTTAQLVPQQITVQTSVVSAAEA------------------------------------- 286

  Fly   285 PAKRSSRMHPADKVDVAEDREQEQNQADELLSEELLGRNLKDEEDDDVDELDENEETKLRGRDED 349
                  ::|......|   |::|....|  |..||..::..|..:|..|...:.|.|.:    ||
  Fly   287 ------KLHQQSPQQV---RQEEAEYID--LPMELPTKSEPDYSEDHGDAAGDAEGTYV----ED 336

  Fly   350 DDDEDEEEDTPMPLDLYQRPNVEPKSAAAATAAQQGGSNSLSGSSNACHTNSSSNSNNNNNNNNN 414
            |...|...|     |.|...|   :.|...|||...|....:.:|.|.....|  .|.:.::..:
  Fly   337 DTYGDMRYD-----DSYFTEN---EDAGNQTAANTSGGGVTATTSKAVVKQQS--QNYSESSFVD 391

  Fly   415 SSSNNNNNTSSGKTSASS 432
            :|.:..|..:...||||:
  Fly   392 TSGDQGNTEAQAATSASA 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mamo	NP_572932.2	BTB	21..118	CDD:279045	45/97 (46%)
		BTB	32..118	CDD:197585	40/86 (47%)
		C2H2 Zn finger	1082..1105	CDD:275368
		C2H2 Zn finger	1116..1137	CDD:275368
		C2H2 Zn finger	1149..1169	CDD:275368
		zf-C2H2	1469..1491	CDD:278523
		C2H2 Zn finger	1471..1491	CDD:275368
		zf-H2C2_2	1483..1506	CDD:290200
		C2H2 Zn finger	1499..1519	CDD:275368
		zf-H2C2_2	1511..1536	CDD:290200
		C2H2 Zn finger	1527..1547	CDD:275368
mod(mdg4)	NP_788698.1	BTB	22..118	CDD:279045	45/96 (47%)
		BTB	33..118	CDD:197585	40/85 (47%)
		FLYWCH	452..512	CDD:282369
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	68	1.000	Domainoid score	I9675
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.010