DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AMPdeam and FAC1

DIOPT Version :9

Sequence 1:	NP_001285233.1	Gene:	AMPdeam / 32352	FlyBaseID:	FBgn0052626	Length:	798	Species:	Drosophila melanogaster
Sequence 2:	NP_565886.1	Gene:	FAC1 / 818408	AraportID:	AT2G38280	Length:	839	Species:	Arabidopsis thaliana

Alignment Length:	762	Identity:	354/762 - (46%)
Similarity:	472/762 - (61%)	Gaps:	67/762 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 PLGSKAS---GKSLNACTSMSMPQKPSSLRATCDLADSPVDEKAEADVEVTNE--ISAPYEVPQF 99
            |...:||   ..|:....|...|..|.|..|:....:|.  |:::.|..:||.  :.|.|
plant   116 PSEGRASVHGASSIRKTGSFVRPISPKSPVASASAFESV--EESDDDDNLTNSEGLDASY----- 173

  Fly   100 PIEQIEKKLQIQRHLNEKQATGPRPVATAAVLATNRESSSSTEGRESAVTMERNDADI------- 157
              .|.....::....||:|         .::.|::...|.|..|....|..:...|||
plant   174 --LQANGDNEMPADANEEQ---------ISMAASSMIRSHSVSGDLHGVQPDPIAADILRKEPEQ 227

  Fly   158 -NFQRVSISGEDTSGVPLEDLERASTLLIEALRLRSHYMAMSDQSFPSTTARFLKTVKLKDRINN 221
             .|.|:::..|    ||..|...|...|.|.|.||..|:      |..|.|.:.|.|
plant   228 ETFVRLNVPLE----VPTSDEVEAYKCLQECLELRKRYV------FQETVAPWEKEV-------- 274

  Fly   222 LPVKEVSDVHLRHSPMKITNPWNVEFP---NDEDFKIKPLNGVFHIYENDDESSEIKYEYPDMSQ 283
                 :||   ..:|...|.|: ..:|   :|..|:::  :||.|::.|.|...:: :...|.:.
plant   275 -----ISD---PSTPKPNTEPF-AHYPQGKSDHCFEMQ--DGVVHVFANKDAKEDL-FPVADATA 327

  Fly   284 FVNDMQVMCNMIADGPLKSFCYRRLCYLSSKYQMHVLLNELRELAAQKAVPHRDFYNTRKVDTHI 348
            |..|:..:..:||.|.:::.|:|||..|..|:.:|::||..:|..|||:.|||||||.||||||:
plant   328 FFTDLHHVLKVIAAGNIRTLCHRRLVLLEQKFNLHLMLNADKEFLAQKSAPHRDFYNVRKVDTHV 392

  Fly   349 HAASCMNQKHLLRFIKKTLKNNANEVVTVTNGQQMTLAQVFQSMNLTTYDLTVDMLDVHADRNTF 413
            |.::||||||||||||..|:...:|||...:|..:||.:||:|::||.|||.||:||||||::||
plant   393 HHSACMNQKHLLRFIKSKLRKEPDEVVIFRDGTYLTLREVFESLDLTGYDLNVDLLDVHADKSTF 457

  Fly   414 HRFDKFNSKYNPIGESRLREVFLKTDNYLNGKYFAQIIKEVAFDLEESKYQNAELRLSIYGKSPD 478
            |||||||.||||.|:|||||:|||.||.:.|::..:|.|:|..|||.||||.||.|:||||:...
plant   458 HRFDKFNLKYNPCGQSRLREIFLKQDNLIQGRFLGEITKQVFSDLEASKYQMAEYRISIYGRKMS 522

  Fly   479 EWYKLAKWAIDNDVYSSNIRWLIQIPRLFDIFKSNKMMKSFQEILNNIFLPLFEATARPSKHPEL 543
            ||.:||.|.::||:||.|:.||||:|||::|:|...::.|||.||:|||:||||||..|..||:|
plant   523 EWDQLASWIVNNDLYSENVVWLIQLPRLYNIYKDMGIVTSFQNILDNIFIPLFEATVDPDSHPQL 587

  Fly   544 HRFLQYVIGFDSVDDESKPE-NPLFDNDVPRPEEWTYEENPPYAYYIYYMYANMTVLNKFRQSRN 607
            |.||:.|:|||.|||||||| .|  ...:|.|.:||...||.::||:||.|||:.||||.|:|:.
plant   588 HVFLKQVVGFDLVDDESKPERRP--TKHMPTPAQWTNAFNPAFSYYVYYCYANLYVLNKLRESKG 650

  Fly   608 MNTFVLRPHCGEAGPVQHLVCGFLMAENISHGLLLRKVPVLQYLYYLTQIGIAMSPLSNNSLFLN 672
            |.|..||||.||||.:.||...||...:|:||:.|||.|||||||||.|||:||||||||||||:
plant   651 MTTITLRPHSGEAGDIDHLAATFLTCHSIAHGINLRKSPVLQYLYYLAQIGLAMSPLSNNSLFLD 715

  Fly   673 YHRNPLPEYLARGLIISLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSSCDMCELARNSVMMSGFP 737
            |||||.|.:..|||.:|||||||||.|.|||||:|||||||.|||||:||:||:|||||..|||.
plant   716 YHRNPFPVFFLRGLNVSLSTDDPLQIHLTKEPLVEEYSIAASVWKLSACDLCEIARNSVYQSGFS 780

  Fly   738 HAIKQQWLGPIYYEDGIMGNDITRTNVPEIRVAYRYETLLDELSNIF 784
            ||:|..|:|..||:.|..||||.:||||.|||.:|.....:|:..::
plant   781 HALKSHWIGKDYYKRGPDGNDIHKTNVPHIRVEFRDTIWKEEMQQVY 827

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AMPdeam	NP_001285233.1	PLN03055	248..784	CDD:178613	303/539 (56%)
AMPdeam	NP_001285233.1	AMPD	284..780	CDD:238644	293/496 (59%)
FAC1	NP_565886.1	PLN02768	1..839	CDD:215411	354/762 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	544	1.000	Domainoid score	I56
eggNOG	1	0.900	-	-		E1_COG1816
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2979
Inparanoid	1	1.050	645	1.000	Inparanoid score	I178
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D49756at2759
OrthoFinder	1	1.000	-	-		FOG0001065
OrthoInspector	1	1.000	-	-		oto3077
orthoMCL	1	0.900	-	-		OOG6_100681
Panther	1	1.100	-	-	LDO	PTHR11359
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X640
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.830