DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AMPdeam and ampd1

DIOPT Version :9

Sequence 1:	NP_001285233.1	Gene:	AMPdeam / 32352	FlyBaseID:	FBgn0052626	Length:	798	Species:	Drosophila melanogaster
Sequence 2:	XP_017212786.1	Gene:	ampd1 / 393867	ZFINID:	ZDB-GENE-040426-1906	Length:	723	Species:	Danio rerio

Alignment Length:	635	Identity:	338/635 - (53%)
Similarity:	461/635 - (72%)	Gaps:	18/635 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 NFQRVSISGEDTSGVPLEDLERASTLLIEALRLRSHYMAMSDQSFPSTTARFLK-----TVKLKD 217
            :||||||:|:..:||.::|.|.|...|..||.:|..||.|:.|.||:|.::||:     |.|.:|
Zfish    91 HFQRVSITGDYAAGVTMDDFELACKGLYRALTIREKYMRMALQRFPNTPSQFLRKIEGETWKPED 155

  Fly   218 RINNLPVKEVSDVHLRHSPMKITNPW-NVEFPNDEDFKIKPLNGVFHIYEN---DDESSEIKYEY 278
            ::  |||       ....|....:|: ..:||.:..:..:..:||.::|::   .|:...:.:..
Zfish   156 QV--LPV-------FTPLPKPGEDPFCTKDFPPNLGYVARMKDGVIYVYKDAAAADKHQPLNHPG 211

  Fly   279 PDMSQFVNDMQVMCNMIADGPLKSFCYRRLCYLSSKYQMHVLLNELRELAAQKAVPHRDFYNTRK 343
            ||::.|::||..:..:||.||.|::.:|||.:|.||:.:|.:|||:.|:...|..|||||||.||
Zfish   212 PDLATFIDDMNFLIALIAQGPTKTYTHRRLKFLMSKFNVHEMLNEMEEMKELKKNPHRDFYNCRK 276

  Fly   344 VDTHIHAASCMNQKHLLRFIKKTLKNNANEVVTVTNGQQMTLAQVFQSMNLTTYDLTVDMLDVHA 408
            ||||||||:|||||||||||||:.:.:|:.||.|..|:::||.::|.|:||..||||||.|||||
Zfish   277 VDTHIHAAACMNQKHLLRFIKKSYRVDADRVVHVLKGKEVTLKELFASLNLHPYDLTVDSLDVHA 341

  Fly   409 DRNTFHRFDKFNSKYNPIGESRLREVFLKTDNYLNGKYFAQIIKEVAFDLEESKYQNAELRLSIY 473
            .|.||.||||||:||||:|.|.||::::||:|:::|:|||.||||||.|||:::||.||.|||||
Zfish   342 GRQTFQRFDKFNAKYNPVGASELRDLYMKTENHISGEYFATIIKEVASDLEDARYQYAEPRLSIY 406

  Fly   474 GKSPDEWYKLAKWAIDNDVYSSNIRWLIQIPRLFDIFKSNKMMKSFQEILNNIFLPLFEATARPS 538
            |.:|:||.||:.|...:.|:|.:::|:||:||::|||:....:..|.::|.|||||:|:||..|:
Zfish   407 GCNPNEWAKLSSWFNKHRVFSPHLKWMIQVPRIYDIFRGRNFVPHFGKMLENIFLPVFQATIDPN 471

  Fly   539 KHPELHRFLQYVIGFDSVDDESKPENPLFDNDVPRPEEWTYEENPPYAYYIYYMYANMTVLNKFR 603
            .:|||..||::|.||||||||||....:|....|:||||...:||.|.|:|||||||:.:||:.|
Zfish   472 SNPELSVFLKHVTGFDSVDDESKHSGHMFSTKSPKPEEWDIVKNPSYTYWIYYMYANIAILNQLR 536

  Fly   604 QSRNMNTFVLRPHCGEAGPVQHLVCGFLMAENISHGLLLRKVPVLQYLYYLTQIGIAMSPLSNNS 668
            :.|.||||..||||||||.|.||:..|:.|:||||||.|:|.|||||||||.|:.||||||||||
Zfish   537 KERGMNTFQFRPHCGEAGAVTHLLACFMTADNISHGLNLKKSPVLQYLYYLAQVPIAMSPLSNNS 601

  Fly   669 LFLNYHRNPLPEYLARGLIISLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSSCDMCELARNSVMM 733
            |||.|::|||.|:..:||::|||||||:|||:|||||||||:|||||:|||:|||||:|||||:.
Zfish   602 LFLEYNKNPLLEFHKKGLMVSLSTDDPMQFHYTKEPLMEEYAIAAQVFKLSTCDMCEIARNSVLQ 666

  Fly   734 SGFPHAIKQQWLGPIYYEDGIMGNDITRTNVPEIRVAYRYETLLDELSNI 783
            ||.....|..:||..|.:||..||||.:|||.:||:||||||...||:.|
Zfish   667 SGLSAEEKIHFLGTSYLQDGPEGNDIRKTNVAQIRMAYRYETQCYELNLI 716

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AMPdeam	NP_001285233.1	PLN03055	248..784	CDD:178613	304/539 (56%)
AMPdeam	NP_001285233.1	AMPD	284..780	CDD:238644	294/495 (59%)
ampd1	XP_017212786.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	1.000	Domainoid score	I11432
eggNOG	1	0.900	-	-		E1_COG1816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D115023at33208
OrthoFinder	1	1.000	-	-		FOG0001065
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100681
Panther	1	1.100	-	-	O	PTHR11359
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X640
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.780