Protein Alignment AMPdeam and ada1

DIOPT Version :10

• Sequence 1: NP_001285233.1
• Gene: AMPdeam / 32352
• FlyBaseID: FBgn0052626
• Length: 798
• Species: Drosophila melanogaster
• Sequence 2: NP_595153.2
• Gene: ada1 / 2540105
• PomBaseID: SPBC106.04
• Length: 831
• Species: Schizosaccharomyces pombe
• Alignment Length: 792
• Identity: 354/792 - (44%)
• Similarity: 475/792 - (59%)
• Gaps: 105/792 - (13%)

  Fly    56 MSMPQK----PSSLRATCDLADSPVDEKAEADVEVTNEISAP--YEVPQFPIEQIEKKLQIQRHL 114
            |:|.|:    |:....|..|.....:..|..|.||.   :||  .:.|.|.. ..|:.|   ||.
pombe     1 MNMEQEDDQVPAVAAETVPLKRYVTNPGANRDEEVA---AAPSSQDTPYFDY-AYERSL---RHQ 58

  Fly   115 NEKQATGPRPVATAAVLATN-----RESSSSTEGRESAVTME--RNDADINFQRVSISGEDTSGV 172
            :.|            .||.|     |:...|...|..:|:..  ||..|:|..:..    ..||.
pombe    59 DAK------------FLAMNGTQNGRDGLPSKSPRRPSVSASTVRNSDDVNHSKAG----PGSGK 107

  Fly   173 PLEDLERASTLLIEALRLRSHYMAMSDQSF------PSTTARFLKTVKLKDRINNLPVKEVSDVH 231
            .|.|     ||..:...:...::...|.:.      |.|....::|.      :.|...|:::::
pombe   108 LLND-----TLQSKISSIHMPHVQQGDNAVVSSVGGPETDPGNMETT------DPLFSDELAEIY 161

  Fly   232 L--------RHSPMKIT------NP-----WNVEFP------------NDEDFKIKPL------- 258
            |        ||..::::      ||     | :.:|            |..|.||..:
pombe   162 LSIHKCMDMRHKYIRVSLQGELDNPIDDDSW-IIYPDCKEGEDDTGLFNFADCKIPGIENEMEYH 225

  Fly   259 ---NGVFHIYENDDE--SSEIKYEYPDMSQFVNDMQVMCNMIADGPLKSFCYRRLCYLSSKYQMH 318
               .|:|.:||||..  :....:..|.:..:..|::.:.:..:|||.|||.:|||.||..::.|:
pombe   226 MDHQGIFQVYENDSAYIAGTPSFHIPTIRDYYIDLEFLLSASSDGPSKSFSFRRLQYLEGRWNMY 290

  Fly   319 VLLNELRELAAQKAVPHRDFYNTRKVDTHIHAASCMNQKHLLRFIKKTLKNNANEVVTVTNGQQM 383
            :||||.:|||..|.||||||||.||||||:|.::..||||||||||..|:...||.|...:|:.:
pombe   291 MLLNEYQELADTKKVPHRDFYNVRKVDTHVHHSALANQKHLLRFIKAKLRKCPNEKVIWRDGKFL 355

  Fly   384 TLAQVFQSMNLTTYDLTVDMLDVHADRNTFHRFDKFNSKYNPIGESRLREVFLKTDNYLNGKYFA 448
            ||.:||.|:.||:|||::|.||:||..:|||||||||.|||||||||||.:||||||.:||:|.|
pombe   356 TLQEVFDSLKLTSYDLSIDTLDMHAHTDTFHRFDKFNLKYNPIGESRLRTIFLKTDNDINGRYLA 420

  Fly   449 QIIKEVAFDLEESKYQNAELRLSIYGKSPDEWYKLAKWAIDNDVYSSNIRWLIQIPRLFDIFKSN 513
            ::.|||..||...|||.||.|:||||::.:||.|||.|.|||:::|.|:|||||:|||:|::|.:
pombe   421 ELTKEVFTDLRTQKYQMAEYRISIYGRNREEWDKLAAWIIDNELFSPNVRWLIQVPRLYDVYKKS 485

  Fly   514 KMMKSFQEILNNIFLPLFEATARPSKHPELHRFLQYVIGFDSVDDESKPENPLFDNDVPRPEEWT 578
            .::::|:|::.|:|.||||.|..|..||:||.|||.||||||||||||||...| ...|.|:.|.
pombe   486 GIVETFEEVVRNVFEPLFEVTKDPRTHPKLHVFLQRVIGFDSVDDESKPERRTF-RKFPYPKHWD 549

  Fly   579 YEENPPYAYYIYYMYANMTVLNKFRQSRNMNTFVLRPHCGEAGPVQHLVCGFLMAENISHGLLLR 643
            ...||||:|::||||||||.||.:|:.|..|||||||||||||...||...||::..|:||:|||
pombe   550 INLNPPYSYWLYYMYANMTSLNSWRKIRGFNTFVLRPHCGEAGDTDHLASAFLLSHGINHGILLR 614

  Fly   644 KVPVLQYLYYLTQIGIAMSPLSNNSLFLNYHRNPLPEYLARGLIISLSTDDPLQFHFTKEPLMEE 708
            |||.||||:||.||.|||||||||:|||.|.:||...|..|||.:||||||||||.||:|||:||
pombe   615 KVPFLQYLWYLDQIPIAMSPLSNNALFLAYDKNPFLTYFKRGLNVSLSTDDPLQFAFTREPLIEE 679

  Fly   709 YSIAAQVWKLSSCDMCELARNSVMMSGFPHAIKQQWLGPIYYEDGIMGNDITRTNVPEIRVAYRY 773
            |::|||::|||:.||||||||||:.|||...:|::|||..:       .||.|||||.||:|||.
pombe   680 YAVAAQIYKLSAVDMCELARNSVLQSGFERQLKERWLGVDF-------QDIDRTNVPIIRLAYRA 737

  Fly   774 ETLLDELSNIFK 785
            .||..|::.:.|
pombe   738 LTLTQEIALVNK 749

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPdeam	NP_001285233.1	AMPD	284..780	CDD:238644	292/495 (59%)
ada1	NP_595153.2	AMP_deaminase	123..753	CDD:437158	318/642 (50%)