Protein Alignment AMPdeam and Ampd3

DIOPT Version :10

• Sequence 1: NP_001285233.1
• Gene: AMPdeam / 32352
• FlyBaseID: FBgn0052626
• Length: 798
• Species: Drosophila melanogaster
• Sequence 2: NP_113732.2
• Gene: Ampd3 / 25095
• RGDID: 2111
• Length: 801
• Species: Rattus norvegicus
• Alignment Length: 783
• Identity: 379/783 - (48%)
• Similarity: 524/783 - (66%)
• Gaps: 56/783 - (7%)

  Fly    54 TSMSMPQKPSSLRATCDLADSP--VDEKAEADV---EVTNEISAPYEVPQ-FPIEQIE-KKLQIQ 111
            |...||::...|..: ||.:..  :.||..|.|   |.:.::.:.:.||: .||.|.| |:.::|
  Rat    33 TKTEMPRQFPKLNMS-DLDEHVRLLAEKVFAKVLREEDSKDVMSLFTVPEDCPIGQKEAKERELQ 96

  Fly   112 RHLNEKQAT---------------------------GPRPVATAAVLATNRESSSSTEGRESAVT 149
            :.|.|:::.                           ||..|:.|....|.....::::...:...
  Rat    97 KELAEQKSVETAKRKKSFKMIRSQSMSLQMPTQDWKGPPSVSPAMSPTTPLVLGAASKPGLAPYD 161

  Fly   150 MERNDADINFQRVSISGEDTSGVPLEDLERASTLLIEALRLRSHYMAMSDQSFPSTTARFLKTVK 214
            |.      .:|||:|||:..:|:.:||.|:|:..|.:||.:|..|..::...||.|||::
  Rat   162 MP------EYQRVTISGDYCAGITVEDYEQAAKSLAKALMIREKYARLAYHRFPRTTAQY----- 215

  Fly   215 LKDRINNLPVKE-VSDVHLRHSPMKITNPWNVE-FPNDEDFKIKPLNGVFHIYEND---DESSEI 274
            |..:..::|::| :.|.|  ..|:...:|:.:: .|.:..:.::...||..:|:|.   :.....
  Rat   216 LAHQGESVPLEEGLPDFH--PPPLPQEDPYCLDNAPPNLGYLVRMQGGVLFVYDNQTMLERQEPH 278

  Fly   275 KYEYPDMSQFVNDMQVMCNMIADGPLKSFCYRRLCYLSSKYQMHVLLNELRELAAQKAVPHRDFY 339
            ...|||:..::.||..:..:|.|||.|::|:|||.:|.||:.:|.:|||:.|....|:.||||||
  Rat   279 SLPYPDLETYIVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFY 343

  Fly   340 NTRKVDTHIHAASCMNQKHLLRFIKKTLKNNANEVVTVTNGQQMTLAQVFQSMNLTTYDLTVDML 404
            |.||||||||||:||||||||||||.|.:...:..|....|:::||.|||.|:::..||||||.|
  Rat   344 NVRKVDTHIHAAACMNQKHLLRFIKYTYQTEPDRTVAEKLGRKITLRQVFDSLHMDPYDLTVDSL 408

  Fly   405 DVHADRNTFHRFDKFNSKYNPIGESRLREVFLKTDNYLNGKYFAQIIKEVAFDLEESKYQNAELR 469
            ||||.|.||||||||||||||:|.|.||:::|||:|||.|:|||:::||||.:||:||||.:|.|
  Rat   409 DVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEDSKYQYSEPR 473

  Fly   470 LSIYGKSPDEWYKLAKWAIDNDVYSSNIRWLIQIPRLFDIFKSNKMMKSFQEILNNIFLPLFEAT 534
            |||||:||.||..||:|.|.:.|||.|:||:||:||::|||:|.|::.||.::|.|||||||:||
  Rat   474 LSIYGRSPKEWSSLARWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPSFGKMLENIFLPLFQAT 538

  Fly   535 ARPSKHPELHRFLQYVIGFDSVDDESKPENPLFDNDVPRPEEWTYEENPPYAYYIYYMYANMTVL 599
            ..|..|.|||.||:||.||||||||||..:.:|.:..|.|:.||.|:||||:||:||||||:.||
  Rat   539 INPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPSPDLWTSEQNPPYSYYLYYMYANIMVL 603

  Fly   600 NKFRQSRNMNTFVLRPHCGEAGPVQHLVCGFLMAENISHGLLLRKVPVLQYLYYLTQIGIAMSPL 664
            |..|:.|.::||:.||||||||.:.|||..||.|:||||||||:|.|||||||||.||.||||||
  Rat   604 NNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPL 668

  Fly   665 SNNSLFLNYHRNPLPEYLARGLIISLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSSCDMCELARN 729
            |||||||.|.:|||.|:|.:||.:|||||||:|||:|||.|||||:|||||||||:||:||:|||
  Rat   669 SNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARN 733

  Fly   730 SVMMSGFPHAIKQQWLGPIYYEDGIMGNDITRTNVPEIRVAYRYETLLDE---LSNIFKVNQTCS 791
            ||:.||..|..||::||..||::|..||||.:|||.:||:|:|||||.:|   ||:..|..:..:
  Rat   734 SVLQSGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITA 798

  Fly   792 IAD 794
            :||
  Rat   799 LAD 801

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPdeam	NP_001285233.1	AMPD	284..780	CDD:238644	311/498 (62%)
Ampd3	NP_113732.2	AMP_deaminase	163..793	CDD:437158	349/642 (54%)