Protein Alignment AMPdeam and ADA

DIOPT Version :9

• Sequence 1: NP_001285233.1
• Gene: AMPdeam / 32352
• FlyBaseID: FBgn0052626
• Length: 798
• Species: Drosophila melanogaster
• Sequence 2: NP_000013.2
• Gene: ADA / 100
• HGNCID: 186
• Length: 363
• Species: Homo sapiens
• Alignment Length: 223
• Identity: 48/223 - (21%)
• Similarity: 75/223 - (33%)
• Gaps: 60/223 - (26%)

  Fly   548 QYVIGFDSVDDESKPENPLFDNDVPRPEEWTYEENPPYAYYIYYMYANMTVLNKFRQSRNMNTFV 612
            |.|:..|...||:.|.:.|....|.     .|:|......:       .||
Human   175 QTVVAIDLAGDETIPGSSLLPGHVQ-----AYQEAVKSGIH-------RTV-------------- 213

  Fly   613 LRPHCGEAGPVQHL--VCGFLMAENISHGL----------LLRK----VPVLQYLYYLTQIGIAM 661
               |.||.|..:.:  ....|..|.:.||.          .||:    ..:..:..|||.   |.
Human   214 ---HAGEVGSAEVVKEAVDILKTERLGHGYHTLEDQALYNRLRQENMHFEICPWSSYLTG---AW 272

  Fly   662 SPLSNNSLFLNYHRNPLPEYLARGLIISLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSSCDMCEL 726
            .|.:.:::.  ..:|....|       ||:|||||.|   |..|..:|.:..:....:..:...|
Human   273 KPDTEHAVI--RLKNDQANY-------SLNTDDPLIF---KSTLDTDYQMTKRDMGFTEEEFKRL 325

  Fly   727 ARNSVMMSGFPHAIKQQWLGPIYYEDGI 754
            ..|:...|..|...|::.|..:|...|:
Human   326 NINAAKSSFLPEDEKRELLDLLYKAYGM 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AMPdeam	NP_001285233.1	PLN03055	248..784	CDD:178613	48/223 (22%)
		AMPD	284..780	CDD:238644	48/223 (22%)
ADA	NP_000013.2	metallo-dependent_hydrolases	9..347	CDD:320877	46/215 (21%)
		Required for binding to DDP4. /evidence=ECO:0000269|PubMed:15016824	126..143

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900