DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jub and lpp

DIOPT Version :9

Sequence 1:	NP_572930.3	Gene:	jub / 32351	FlyBaseID:	FBgn0030530	Length:	728	Species:	Drosophila melanogaster
Sequence 2:	XP_012818600.1	Gene:	lpp / 779875	XenbaseID:	XB-GENE-951633	Length:	614	Species:	Xenopus tropicalis

Alignment Length:	672	Identity:	185/672 - (27%)
Similarity:	270/672 - (40%)	Gaps:	177/672 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 APTAQILGQRIAPQKHSPVYENLEFY-----GQFDSNHKRAQPQSPGSRQSAILNGYLLMQPI-R 184
            ||:..:..|: .|:|.:||......|     ||.:.:.....|..|...:..       :||: .
Frog    31 APSISVSTQQ-PPKKFAPVVAPKPKYNPYRGGQSEGSDGDFPPPPPPPPEEN-------LQPMPT 87

  Fly   185 AGRFAHTPVPE--------NQGSASLGTTRAA-----------------GGPPPPSGRSAALGPT 224
            .|.....|||:        |.|..::...|::                 ..|..|.........|
Frog    88 LGNLPPPPVPDEAMFNVQINTGGKTIEERRSSLDAEIDSLTSILADLENSSPYKPRTPQGPGSNT 152

  Fly   225 GDLEEHAAPIYENIIPHSGQRAQ--PQASPATATMYQEMQPTSNSSGSSSTAGLDLNALLASPMH 287
            |.|...:|.     .|.:|.:..  |...|.|||.....:|...|:...:.||        ||..
Frog   153 GTLTHPSAG-----TPVTGHKRMIIPNQPPLTATKKSATKPQPQSTSQPAPAG--------SPGA 204

  Fly   288 QR--SISSNTASSSSLGSPTQRYRNLS-------------LPSHLSPVPTAQSVAKLQQHTPVKS 337
            ||  .:.:..|::|:...||...:..|             |..:.||.|......:     |.:|
Frog   205 QRPQPVPAPYATASTPSRPTFNVQVKSAQPSPHFVPPGPQLGQNYSPAPNQYYAPQ-----PTRS 264

  Fly   338 PGGAINVSVNPNYIEDINSSDYVCMTANLHRNTAAGLATGRAAATGAPAQRTVQ----------- 391
            ||..       .|.......:|:......:.....|.:.|..:....|..::||
Frog   265 PGPM-------QYAPQPRGQEYIPPPPARYVEPGYGYSQGNQSKYQDPYYQSVQGYGGRNGSEVP 322

  Fly   392 ---------EP-----PIITSSLAMGMATAA---PPTTSNAPTSAAAAPAAPTSTASLRATPIAM 439
                     ||     |.:....|:|...|.   ||.|...                      .:
Frog   323 YTQQGGWKPEPAYSPIPAVGQQPAVGQQPAGSYQPPNTKKT----------------------YI 365

  Fly   440 TAPLAVATSPTPSQGSTAVNAALKPRRGLTKNLLPYSVTPPRPAGPTEAQR-------KIEELTR 497
            |.|..:   |.|                           ||:|.||..||.       ::|.||:
Frog   366 TDPPYI---PPP---------------------------PPQPKGPYLAQASSLRPEDELERLTK 400

  Fly   498 QLEEEIEQSEEHGEYFGICHTCGEKVKGAGQACQAMGNLYHTNCFICCSCGRALRGKAFYNVHGR 562
            ::..::|..... ||||.|..|||.|.|.|..|.||..::|..||.|.:|...|||:.||.|..:
Frog   401 KMLYDMENPPSE-EYFGRCSRCGENVVGEGTGCTAMDQVFHVECFTCMTCNSKLRGQPFYAVEKK 464

  Fly   563 VYCEEDYMYSGFQQTAEKCAICGHLIMEMILQAMGKSYHPGCFRCCVCNECLDGVPFTVDVDHKI 627
            .:||..|:     :|.|||::|...|||.||:|.||:|||.||.|.||...|||:|||||...:|
Frog   465 AFCEPCYI-----RTLEKCSVCAKPIMERILRATGKAYHPHCFTCVVCFRSLDGIPFTVDASGQI 524

  Fly   628 YCVNDYHRMFAPKCASCGKGITPVEGTDETVRVVSMDKDFHVDCYICEECGMQLTDEPDKRCYPL 692
            :|:.|:|:.|||:|:.|.:.|.|..|.:||||:|::|:||||.||.||:||..|::..::.||||
Frog   525 HCIEDFHKKFAPRCSVCKEPIMPAPGQEETVRIVALDRDFHVQCYRCEDCGSLLSEGENQGCYPL 589

  Fly   693 DGRLLCRGCH---LQRLALQSS 711
            ||.:||:.|:   :|.|..:||
Frog   590 DGHILCKACNAARIQALTAKSS 611

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jub	NP_572930.3	LIM1_Ajuba_like	516..569	CDD:188738	23/52 (44%)
		LIM2_Ajuba_like	581..633	CDD:188741	28/51 (55%)
		LIM3_Ajuba_like	641..702	CDD:188822	30/60 (50%)
lpp	XP_012818600.1	PHA03247	<4..358	CDD:223021	68/359 (19%)
		PRK10263	<171..>341	CDD:236669	36/189 (19%)
		LIM1_TRIP6	418..471	CDD:188736	23/52 (44%)
		LIM	478..537	CDD:413332	32/58 (55%)
		LIM3_TRIP6	538..603	CDD:188820	31/64 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54624
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920