DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jub and Trip6

DIOPT Version :9

Sequence 1:	NP_572930.3	Gene:	jub / 32351	FlyBaseID:	FBgn0030530	Length:	728	Species:	Drosophila melanogaster
Sequence 2:	NP_001121042.1	Gene:	Trip6 / 686323	RGDID:	1583180	Length:	480	Species:	Rattus norvegicus

Alignment Length:	575	Identity:	173/575 - (30%)
Similarity:	241/575 - (41%)	Gaps:	154/575 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 RAQPQ---SPGSRQSAILNGYLLMQPIRAGRFAHTP---------VPENQGSASLGTTRAA---G 209
            ||.|:   .|.:...|.|      ||.....|...|         |||::|...:|:..||   .
  Rat    21 RALPRGTLGPPTAHGATL------QPHPRVNFCPLPPEQCYQPPGVPEDRGPTWVGSHGAAQRLQ 79

  Fly   210 GPPPPSGRSAALGPTGDLEEHAAPIYENIIPHSGQRAQPQASPATATMYQEMQPTSNSSGSSSTA 274
            |.||..|   .:.| |.|:.....:...:....|.|:.....| ....::...|.:...||...:
  Rat    80 GLPPDRG---VIHP-GSLDAEIDSLTSMLADLDGSRSHAPRRP-DRQAFEAPPPHAYRGGSLKPS 139

  Fly   275 GLDLNALLASPMHQRSISSNTASSSSLGSPT-QRYRNLSLPSHLSPV-PTAQSVAKLQQHTPVKS 337
            |    ..:.:||         ..:|..|.|| ..|...|.|:  .|. |....||:     ||:.
  Rat   140 G----GAVPAPM---------LPASPYGGPTPASYATASTPA--GPAFPVQVKVAQ-----PVRG 184

  Fly   338 PG----GAINVS---VNPNYIEDINSSDYVCMTANLHRNTAAGLATGRAAATGAPAQRTVQEPPI 395
            .|    ||...|   ..|::                       ..|||....|| ..|:.:||
  Rat   185 CGLPRRGASQASGPLPGPHF-----------------------PLTGRGEVWGA-GYRSHREP-- 223

  Fly   396 ITSSLAMGMATAAPPTTSNAPTSAAAAPAAPTSTASLRATPIAMTAPLAVATSPTPSQGSTAV-N 459
                                                                .|...:|:..| |
  Rat   224 ----------------------------------------------------GPGVKEGAAGVHN 236

  Fly   460 AALKPRRGLTKNLLPYSVTPPRPAGPTE--AQRKIEELTRQLEEEIEQSEEHGEYFGICHTCGEK 522
            .|...|||           ...|.||..  .:.::|.||::|..::..... |||||.|..||:.
  Rat   237 PAGGGRRG-----------GHEPQGPLSQPPEEELERLTKKLVHDMNHPPS-GEYFGRCGGCGDD 289

  Fly   523 VKGAGQACQAMGNLYHTNCFICCSCGRALRGKAFYNVHGRVYCEEDYMYSGFQQTAEKCAICGHL 587
            |.|.|....|:..::||.||:|.:|...|||:.||.|..|.|||..|:     .|.|||:.|...
  Rat   290 VVGDGAGVVALDRVFHTGCFVCSTCRAQLRGQHFYAVERRAYCESCYV-----ATLEKCSTCSEP 349

  Fly   588 IMEMILQAMGKSYHPGCFRCCVCNECLDGVPFTVDVDHKIYCVNDYHRMFAPKCASCGKGITPVE 652
            |::.||:||||:||||||.|.||:..|||:|||||...:|:|:.|:||.|||:|:.||..|.|..
  Rat   350 ILDRILRAMGKAYHPGCFTCVVCHRGLDGIPFTVDATSQIHCIEDFHRKFAPRCSVCGGAIMPEP 414

  Fly   653 GTDETVRVVSMDKDFHVDCYICEECGMQLTDEPD-KRCYPLDGRLLCRGCHLQRL 706
            |.:||||:|::|:.||:.||.|||||:.|:.|.: :.||||||.:||:.|...|:
  Rat   415 GQEETVRIVALDRSFHIGCYKCEECGLLLSSEGECQGCYPLDGHILCKACSAWRI 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jub	NP_572930.3	LIM1_Ajuba_like	516..569	CDD:188738	23/52 (44%)
		LIM2_Ajuba_like	581..633	CDD:188741	28/51 (55%)
		LIM3_Ajuba_like	641..702	CDD:188822	31/61 (51%)
Trip6	NP_001121042.1	PHA03247	<3..256	CDD:223021	70/354 (20%)
		LIM1_TRIP6	283..336	CDD:188736	23/52 (44%)
		LIM	343..402	CDD:413332	33/58 (57%)
		LIM3_Zyxin_like	403..465	CDD:188743	31/61 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810