DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment jub and ajuba

DIOPT Version :9

Sequence 1:	NP_572930.3	Gene:	jub / 32351	FlyBaseID:	FBgn0030530	Length:	728	Species:	Drosophila melanogaster
Sequence 2:	XP_701366.4	Gene:	ajuba / 572549	ZFINID:	ZDB-GENE-030131-9341	Length:	688	Species:	Danio rerio

Alignment Length:	712	Identity:	234/712 - (32%)
Similarity:	309/712 - (43%)	Gaps:	190/712 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 GNIIAASKYATPR----PVEQ-----IQHTHNGSAQIYAPTAQILGQRIAPQKHSPVY--ENLEF 150
            |.:.::.:.|.|.    ||.:     |:|..:..|.:         :|.:||:.:..|  :.||.
Zfish    75 GKVGSSQRIAPPNNTAVPVAEDCGPGIEHHPSTLAPL---------RRRSPQQRASCYLPDTLEG 130

  Fly   151 YGQFDSNHK--RAQPQ---SPGSR------------QSAILNGYLLMQPIRAGRFAHTPVPENQG 198
            .|..|...:  ...||   ||.||            |..:....||.||..... ...|.|.:..
Zfish   131 RGTCDQMRRGGEGDPQGAYSPNSRAALKQRRYSLELQQLVRRQQLLAQPPPLSS-VPPPYPTHSS 194

  Fly   199 SASLGTTR------------------------AAGGPPPPSGRSAALGPTGDLEEHAAPIYENII 239
            :|.|....                        ::||.|..|||.|:|.
Zfish   195 AARLSAVEPSFLHEMERHKRLSLQEALFYKRLSSGGEPWDSGRPASLS----------------- 242

  Fly   240 PHSGQR------------AQPQASPATATMYQE---MQPTSNSSGSSSTAGLDLNALLASPMHQR 289
             |..||            :.|..||.::...||   ..|.|:.:.|:::.|   .....|||..|
Zfish   243 -HPPQRTHDSSVGGFFFPSAPALSPCSSFSLQESVLASPRSSFASSTASGG---GGGGGSPMGSR 303

  Fly   290 SISSNTASSSSLGSPTQRYRNLSLP---SHLSPVPTAQSVAKLQQHTPVKSPGGAINVSVNPNYI 351
             .|||..|..|||     |.|...|   ..|....|..|...|.|..|.....||..:.|..:.:
Zfish   304 -CSSNRTSGISLG-----YDNRHTPGPAQQLQLSSTQLSGTTLGQAHPAPGKTGAPPIEVWRDCL 362

  Fly   352 EDINSSD-------YVCMTANLHR----------NTAAGLATG-RAAATGAPAQRTVQEPP--II 396
            |.::...       ....|...||          ..:.|...| ||..:.....|..||..  ::
Zfish   363 EGVSGDSRHSYPPALSTHTVTFHRAEPDWGPIDQRGSRGDGVGERARHSDLLGTRYQQELTRLLL 427

  Fly   397 TSSLAMGMATAAPPTTSNAPTSAAAAPAAPTSTASLRATPIAMTAPLAVATSPTPSQGSTAVNAA 461
            ..:...|.|.....|....|.||...|:: |||                 .:||.:.|
Zfish   428 RDAALEGEALLGGLTLKEQPVSATILPSS-TST-----------------PAPTAAPG------- 467

  Fly   462 LKPRRGLTKNLLPYSVTPPRPAGPTEAQRKIEELTRQLEEEIEQSEEHGEYFGICHTCGEKVKGA 526
             ||              |..||...:.|                     ||||.|..||:.|.||
Zfish   468 -KP--------------PEEPAAGVDRQ---------------------EYFGTCVKCGKGVYGA 496

  Fly   527 GQACQAMGNLYHTNCFICCSCGRALRGKAFYNVHGRVYCEEDYMYSGFQQTAEKCAICGHLIMEM 591
            ..||||:.:||||.||.|.||||.||.|.||||:|.|||:||||:||||:.||||::|||||:|.
Zfish   497 DNACQALDSLYHTRCFTCVSCGRTLRNKDFYNVNGSVYCKEDYMFSGFQEAAEKCSVCGHLILEQ 561

  Fly   592 ILQAMGKSYHPGCFRCCVCNECLDGVPFTVDVDHKIYCVNDYHRMFAPKCASCGKGITPVEGTDE 656
            ||||:|.|||||||||.||::.|||||||||..:.:|||:||:|.||||||:|.:.|.|.||::|
Zfish   562 ILQALGNSYHPGCFRCTVCSKALDGVPFTVDYLNNVYCVSDYNRTFAPKCAACLQPILPAEGSEE 626

  Fly   657 TVRVVSMDKDFHVDCYICEECGMQLTDEPDKRCYPLDGRLLCRGCHLQRLALQSS--PHARH 716
            .:|||||:||:|.:||.|||||.||:|||..:|:|||..|||..||:.|:.:..:  ||..|
Zfish   627 ILRVVSMNKDYHFECYHCEECGKQLSDEPGSQCFPLDAHLLCHSCHMSRVCVTHNLPPHNTH 688

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jub	NP_572930.3	LIM1_Ajuba_like	516..569	CDD:188738	33/52 (63%)
		LIM2_Ajuba_like	581..633	CDD:188741	35/51 (69%)
		LIM3_Ajuba_like	641..702	CDD:188822	35/60 (58%)
ajuba	XP_701366.4	LIM1_Ajuba_like	486..539	CDD:188738	33/52 (63%)
		LIM2_Ajuba_like	551..603	CDD:188741	35/51 (69%)
		LIM3_Ajuba_like	611..672	CDD:188822	35/60 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	104	1.000	Domainoid score	I6645
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24219
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	5	4.870