DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jub and fhl3b

DIOPT Version :9

Sequence 1:	NP_572930.3	Gene:	jub / 32351	FlyBaseID:	FBgn0030530	Length:	728	Species:	Drosophila melanogaster
Sequence 2:	NP_001093448.1	Gene:	fhl3b / 555053	ZFINID:	ZDB-GENE-030131-8356	Length:	290	Species:	Danio rerio

Alignment Length:	250	Identity:	61/250 - (24%)
Similarity:	100/250 - (40%)	Gaps:	41/250 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   487 EAQRKIEELTRQLEEEIEQSEEH------------------------------GEYFGICHTCGE 521
            |.:..||..:|:|..|.....|.                              .|:...|..||:
Zfish    42 ECKELIEHNSRELYHEDRHYHEQCFRCSRCSRSLAKESFTCQEDALVCNNCYCNEFSSNCVACGK 106

  Fly   522 KVKGAGQACQAMGNLYHTNCFICCSCGRALRGKAFYNVHGRVYCEEDYMYSGFQQTAEKCAICGH 586
            .|....:..:....::|..||:||.|.:.:..::|.......||..  .|.|  :.|.:||.|..
Zfish   107 TVMPGSKRLEYEDCVWHEECFVCCGCEQPIGAQSFIPDKDEYYCVP--CYEG--RFAPRCAHCKQ 167

  Fly   587 LIMEMILQAMGKSYHPGCFRCCVCNECLDGVPFTVDVDHKIYCVNDYHRMFAPKCASCGKGITPV 651
            .:::..:....:.:|..||.|..|...|.|.|||...:.. |||..:..::|.|||:|.|   |:
Zfish   168 TLVQGGVTYRDEPWHKECFLCTGCKVQLAGQPFTTQGEDP-YCVKCFSNLYAQKCAACEK---PI 228

  Fly   652 EGTDETVRVVSMDKDFHVDCYICEECGMQLTDEPDKRCYPLDGRLLCRGCHLQRL 706
            .|..|...|...::.:|..|:.|..|.:.|.   ....:|....:||:||:.::|
Zfish   229 TGFGEGKYVSFEERQWHKPCFKCSVCSLSLV---GAGFFPHGSMILCKGCNTKKL 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jub	NP_572930.3	LIM1_Ajuba_like	516..569	CDD:188738	13/52 (25%)
		LIM2_Ajuba_like	581..633	CDD:188741	16/51 (31%)
		LIM3_Ajuba_like	641..702	CDD:188822	17/60 (28%)
fhl3b	NP_001093448.1	LIM	<5..33	CDD:295319
		LIM1_FHL3	36..94	CDD:188807	7/51 (14%)
		LIM2_FHL3	98..155	CDD:188811	13/58 (22%)
		LIM3_FHL	162..213	CDD:188732	16/51 (31%)
		LIM4_FHL3	221..276	CDD:188818	17/60 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910