DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jub and lims2

DIOPT Version :9

Sequence 1:	NP_572930.3	Gene:	jub / 32351	FlyBaseID:	FBgn0030530	Length:	728	Species:	Drosophila melanogaster
Sequence 2:	XP_021334342.1	Gene:	lims2 / 553696	ZFINID:	ZDB-GENE-050522-56	Length:	378	Species:	Danio rerio

Alignment Length:	317	Identity:	73/317 - (23%)
Similarity:	113/317 - (35%)	Gaps:	115/317 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   467 GLTKNLLPYSVTPPRPAGPTEAQRKIEELTRQLEEEIEQSEEHGEYF-----------GICHTCG 520
            ||.:|         :.||..|..::         .:::..:|..:::           .:|..|.
Zfish    15 GLQQN---------QTAGEPEVPKR---------SDVKVYKEFCDFYVRYNMTNALANAVCERCK 61

  Fly   521 EKVKGAGQACQAMGNLYHTNCFICCSCGRALRGKAFYNVHGRVYCEEDYMYSGFQQT-AEKCAIC 584
            .......:...:.|.|||..||.|..|.:.|....||...||.|||.|     ||.. |..|..|
Zfish    62 SSFSPTEKMVNSNGELYHEQCFTCAQCFQQLIQGLFYEFEGRKYCEHD-----FQMLFAPCCHQC 121

  Fly   585 GHLIMEMILQAMGKSYHPGCFRCC------------------------------------VCNEC 613
            |..::..:::||..|:||.|| ||                                    ||.:|
Zfish   122 GEFVVGRVIKAMNSSWHPDCF-CCEVCEAVLADVGFVKSGGRPLCRSCHSRQKALSLGKHVCQKC 185

  Fly   614 L-----------------------DGVPFTVD---VDHKIYCVNDYHRMFAPKCASCGKGITPVE 652
            |                       .|...|.|   :..::||:..:.::..|.|.:|.:   |||
Zfish   186 LCVVEEPLMYRSDPYHPDHFNCSHCGKELTADARELKGELYCLPCHDKLGVPICGACRR---PVE 247

  Fly   653 GTDETVRVV-SMDKDFHVDCYICEECGMQLTDEP--DKRCYPLDGRLLCRGCHLQRL 706
            |     ||| :|.|.:||:.::|.:|     ::|  ..|.|...|...|. .|..:|
Zfish   248 G-----RVVNAMGKQWHVEHFVCVKC-----EKPFLGHRHYERKGLAYCE-THYNQL 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jub	NP_572930.3	LIM1_Ajuba_like	516..569	CDD:188738	18/52 (35%)
		LIM2_Ajuba_like	581..633	CDD:188741	21/113 (19%)
		LIM3_Ajuba_like	641..702	CDD:188822	20/63 (32%)
lims2	XP_021334342.1	LIM1_PINCH	57..115	CDD:188717	21/62 (34%)
		LIM2_PINCH	118..169	CDD:188718	12/51 (24%)
		LIM3_PINCH	182..231	CDD:188719	8/48 (17%)
		LIM4_PINCH	237..290	CDD:188720	21/66 (32%)
		LIM5_PINCH	298..351	CDD:188721
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810