DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jub and fhl1a

DIOPT Version :9

Sequence 1:	NP_572930.3	Gene:	jub / 32351	FlyBaseID:	FBgn0030530	Length:	728	Species:	Drosophila melanogaster
Sequence 2:	NP_001007288.1	Gene:	fhl1a / 399646	ZFINID:	ZDB-GENE-040206-1	Length:	297	Species:	Danio rerio

Alignment Length:	221	Identity:	56/221 - (25%)
Similarity:	93/221 - (42%)	Gaps:	32/221 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   497 RQLEEEIEQSEEHGEYFGICHTCGEKVKGAGQACQA--------------MGNLYHTNCFICCSC 547
            :.|..|..|:::.|:.  :|..||:  :.....||.              ...::|..||.|..|
Zfish    89 KPLANEPFQAKDDGKI--MCGKCGD--RDGSPRCQGCYKVITPGCKNVEYKHKVWHEECFTCFEC 149

  Fly   548 GRALRGKAFYNVHGRVYCEEDYMYSGFQQTAEKCAICGHLIMEMILQAMGKSYHPGCFRCCVCNE 612
            .:.:|.::|......:||...:.    ::.|:.|..|...|....|....:.:|..||.|..|.:
Zfish   150 KQPIRTQSFLTKGDDMYCTPCHE----KKFAKHCVRCKEAITSGGLTYQDQPWHSECFVCHTCKK 210

  Fly   613 CLDGVPFTVDVDHKIYCVNDYHRMFAPKCASCGKGITPVEGTDETVRVVSM-DKDFHVDCYICEE 676
            .|.|..||...| :.|||:.|....|.||:.|.   .|:.|......||:. ||.:|..|:.|::
Zfish   211 PLAGARFTAHED-QFYCVDCYKSDVAKKCSGCQ---NPITGFGRGTNVVNYEDKSWHEYCFNCKK 271

  Fly   677 CGMQLTDEPDKRCYPLDGR-LLCRGC 701
            |.:.:.   .|| :.::|. :.|..|
Zfish   272 CSLSMA---HKR-FVINGEDIYCSDC 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jub	NP_572930.3	LIM1_Ajuba_like	516..569	CDD:188738	14/66 (21%)
		LIM2_Ajuba_like	581..633	CDD:188741	17/51 (33%)
		LIM3_Ajuba_like	641..702	CDD:188822	17/63 (27%)
fhl1a	NP_001007288.1	LIM	<21..49	CDD:295319
		LIM1_FHL1	56..110	CDD:188730	5/22 (23%)
		LIM2_FHL1	118..175	CDD:188808	11/60 (18%)
		LIM3_FHL1	179..231	CDD:188813	17/52 (33%)
		LIM4_FHL1	234..297	CDD:188734	19/67 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900