DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jub and Prickle1

DIOPT Version :9

Sequence 1:	NP_572930.3	Gene:	jub / 32351	FlyBaseID:	FBgn0030530	Length:	728	Species:	Drosophila melanogaster
Sequence 2:	NP_955428.1	Gene:	Prickle1 / 315259	RGDID:	735090	Length:	831	Species:	Rattus norvegicus

Alignment Length:	224	Identity:	54/224 - (24%)
Similarity:	97/224 - (43%)	Gaps:	25/224 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   488 AQRKIEELTRQLEEEIEQSEEHGEYFGICHTCGEKVKGAGQACQAM----GNLYHTNCFICCSCG 548
            ||||.|.|.|...:.:.::..|    .:|..||.::.|...|..|.    |..:|.:||:|.:|.
  Rat   102 AQRKKEALGRGTIKLLSRAMMH----AVCEQCGLQMNGGEVAVFASRAGPGVCWHPSCFVCFTCN 162

  Fly   549 RALRGKAFYNVHGRVYCEEDYMYSGFQQTAEKCAICGHLIM-EMILQAMGKSYHPGCFRCCVCNE 612
            ..|....::...|:::|...:.    :....:|:.|..:|. :...:|.|:.:|...|.|..|..
  Rat   163 ELLVDLIYFYQDGKIHCGRHHA----ELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECET 223

  Fly   613 CLDGVPFTVDVDHKIYCVNDYHRMFAPKCASCGKGITPVEGTDETVRVVSMDKDFHVD--CYICE 675
            .|.|..:.:. |.:.:|...:..::|..|.:||:.|    |.|. .::....:.:|..  |:.|.
  Rat   224 VLGGQRYIMK-DGRPFCCGCFESLYAEYCETCGEHI----GVDH-AQMTYDGQHWHATEACFSCA 282

  Fly   676 ECGMQLTDEPDKRCYPLDGRLLC-RGCHL 703
            :|...|...|   ..|..|::.| :.|.|
  Rat   283 QCKASLLGCP---FLPKQGQIYCSKTCSL 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jub	NP_572930.3	LIM1_Ajuba_like	516..569	CDD:188738	15/56 (27%)
		LIM2_Ajuba_like	581..633	CDD:188741	13/52 (25%)
		LIM3_Ajuba_like	641..702	CDD:188822	15/63 (24%)
Prickle1	NP_955428.1	PET_Prickle	22..118	CDD:193602	7/15 (47%)
		LIM1_Prickle_1	126..184	CDD:188867	15/57 (26%)
		LIM2_Prickle	189..244	CDD:188802	13/55 (24%)
		LIM3_Prickle	249..307	CDD:188804	15/65 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	314..346
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	664..688
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	763..831
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810