DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment jub and LMCD1

DIOPT Version :9

Sequence 1:	NP_572930.3	Gene:	jub / 32351	FlyBaseID:	FBgn0030530	Length:	728	Species:	Drosophila melanogaster
Sequence 2:	NP_055398.1	Gene:	LMCD1 / 29995	HGNCID:	6633	Length:	365	Species:	Homo sapiens

Alignment Length:	384	Identity:	82/384 - (21%)
Similarity:	123/384 - (32%)	Gaps:	125/384 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   361 CMTANLHRNTAAG-------LATGRAAATGAPAQRTVQEPPIITSSLAMGMATAAPPTTSNAPTS 418
            |:|::|..:...|       .:|..|...|....|..:...:|.::         |..|...||
Human    58 CLTSDLEDDRKIGRLLMDSKYSTLTARVKGGDGIRIYKRNRMIMTN---------PIATGKDPT- 112

  Fly   419 AAAAPAAPTSTASLRATPIAMTAPLA---VATSPTPSQGSTAVNAALKPRRGLTKNLLPYSVTPP 480
                    ..|.:....|..:|..|.   :...|...|..|....|...||.|...|..|...|.
Human   113 --------FDTITYEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPS 169

  Fly   481 RPAGPTEAQRKI-EELTRQLEEEI----------------EQSEEHGEYFGICHTCGEKVKGA-G 527
            |..|..|.:.|: ||..:|.:.|.                |:.::.           ||.:|| .
Human   170 RCRGLLENELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQ-----------EKPEGAET 223

  Fly   528 QACQAMGNLYHTNC---FICCSCGRALRGKAFYNVHGRVYCEEDYMYS---GFQQTAEKCAICGH 586
            .|....|:|...:.   ::|..|            .|....:...:||   |:
Human   224 TAATTNGSLSDPSKEVEYVCELC------------KGAAPPDSPVVYSDRAGY------------ 264

  Fly   587 LIMEMILQAMGKSYHPGCFRCCVCNECL--------DGVPFTVDVDHKIYCVNDYHRMFAPKCAS 643
                      .|.:||.||.|..|:|.|        ||.|         :|...|.....|:|:.
Human   265 ----------NKQWHPTCFVCAKCSEPLVDLIYFWKDGAP---------WCGRHYCESLRPRCSG 310

  Fly   644 CGKGITPVEGTDETVRVVSMDKDFHVDCYICEECGMQLTDEPDKRCYPL-DGRLLCRGC 701
            |.:.|.    .::..||  .|..:|...::||.|...|:.    |.|.: .|:|||..|
Human   311 CDEIIF----AEDYQRV--EDLAWHRKHFVCEGCEQLLSG----RAYIVTKGQLLCPTC 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jub	NP_572930.3	LIM1_Ajuba_like	516..569	CDD:188738	10/56 (18%)
		LIM2_Ajuba_like	581..633	CDD:188741	13/59 (22%)
		LIM3_Ajuba_like	641..702	CDD:188822	18/62 (29%)
LMCD1	NP_055398.1	PET_testin	116..203	CDD:193604	21/86 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	200..235		8/45 (18%)
		LIM1_Testin_like	243..300	CDD:188726	19/99 (19%)
		LIM	306..359	CDD:295319	18/62 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810