DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment jub and Fhl1

DIOPT Version :9

Sequence 1:	NP_572930.3	Gene:	jub / 32351	FlyBaseID:	FBgn0030530	Length:	728	Species:	Drosophila melanogaster
Sequence 2:	XP_006527864.1	Gene:	Fhl1 / 14199	MGIID:	1298387	Length:	339	Species:	Mus musculus

Alignment Length:	253	Identity:	60/253 - (23%)
Similarity:	94/253 - (37%)	Gaps:	57/253 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   516 CHTCGEKVKGAGQACQAMGNLYHTNCFICCSCGRALRGKAFYNVHGRVYCEEDYMYSGFQQTAEK 580
            |..|.:.:....:........:|.|||.|..|...|..:.|.:..|::.|.:    ...::.:.:
Mouse    56 CVDCRKPISADAKEVHYKNRYWHDNCFRCAKCLHPLASETFVSKDGKILCNK----CATREDSPR 116

  Fly   581 CAICGHLIM--EMILQAMGKSYHPGCFRCCVCNECL-DGVPFTVDVDHKIYCVNDYHRMFAPKCA 642
            |..|...|:  :..::..|..:|..||.|..|.:.: .|..|....|  .|||..:...||..|.
Mouse   117 CKGCFKAIVAGDQNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGED--FYCVTCHETKFAKHCV 179

  Fly   643 SCGKGITPVEGTDETVRVVSMDKDFHVDCYICEEC-----GMQLTDEPDK----RCY-------- 690
            .|.|.||       :..:...|:.:|.:|::|..|     |.:.|...|:    .||
Mouse   180 KCNKAIT-------SGGITYQDQPWHAECFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKC 237

  Fly   691 -----PLDG-RLLCR------------GCHLQRLALQSSPHA----RHQ--EPVCASY 724
                 |:.| |.:.|            .||.:||.|...|.|    ||.  |..|.|:
Mouse   238 AGCKNPITGKRTVSRVSHPVSKARKSPVCHGKRLPLTLFPSANLRGRHPGGERTCPSW 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jub	NP_572930.3	LIM1_Ajuba_like	516..569	CDD:188738	12/52 (23%)
		LIM2_Ajuba_like	581..633	CDD:188741	15/54 (28%)
		LIM3_Ajuba_like	641..702	CDD:188822	19/95 (20%)
Fhl1	XP_006527864.1	LIM	<21..49	CDD:351770
		LIM1_FHL1	56..109	CDD:188730	12/56 (21%)
		LIM2_FHL1	117..174	CDD:188808	15/58 (26%)
		LIM3_FHL1	178..230	CDD:188813	14/58 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1704
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810