DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment jub and wtip

DIOPT Version :9

Sequence 1:	NP_572930.3	Gene:	jub / 32351	FlyBaseID:	FBgn0030530	Length:	728	Species:	Drosophila melanogaster
Sequence 2:	XP_002935833.2	Gene:	wtip / 100493332	XenbaseID:	XB-GENE-953279	Length:	698	Species:	Xenopus tropicalis

Alignment Length:	655	Identity:	248/655 - (37%)
Similarity:	336/655 - (51%)	Gaps:	156/655 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 NQDYKLYE------RGNIIAASKYATPR-----PVEQIQHTHNGSA------QIYAPTAQILGQR 135
            :|::..|.      ..|.::..|:::||     |.:|.::|...|:      .:.:|.:......
Frog   173 SQEHSKYSSPRSSISSNALSLDKFSSPRCSLVVPGQQEKYTSPRSSLGQYEGGVLSPRSSYASTT 237

  Fly   136 IAPQKHSPVYENLEFYGQFDSNHKRAQPQSPGSRQSAILNGY----LLMQPIRAGRFAHTPVPEN 196
            ....|||....:|..|   |...|   |.|  :|.|.|..||    :..:...|.:::.|..|.:
Frog   238 SDTSKHSSPRASLTSY---DCGSK---PSS--NRTSGISMGYDQRHISPRSSTASQYSCTTSPRS 294

  Fly   197 QGSASLGTTRAAGGPPPPSGRSAALGPTGDLEEHAAPIYENIIPHSGQRAQPQASPATATMYQEM 261
            ..|.|   .....|.|...|    :|..|.|                      .||.::...||
Frog   295 SYSDS---RYMPSGNPDLDG----VGGHGSL----------------------VSPRSSLCLQE- 329

  Fly   262 QPTSNSSGSSSTAGLDLNALLASPMHQRSISSNTASSSSLGSPTQRYRNLSLPSHLSPVPTAQSV 326
                   |.|:|.| ..|..:.||....|..|:.:|.||.|| ...|.:|::||     |.:..:
Frog   330 -------GRSATLG-SCNPSVVSPRSSISSHSSRSSRSSRGS-MGAYADLTVPS-----PRSSML 380

  Fly   327 -AKLQQHTPVKSPGGAINVSVNPNYIEDINSSDYVCMTANLHRNTAAGLATGRAAATGAPAQRTV 390
             ..||:.|.|:..|.|.:..|                                  .|.:|.::..
Frog   381 GTSLQEETLVQDVGEACHYKV----------------------------------LTQSPPRQEQ 411

  Fly   391 QEPPIITSSLAMGMATAAPPTTSNAPTSAAAAPAAPTSTASLRATPIAMTAPLAVATSPTPSQGS 455
            |:...|||              |:.|.|.|.|                       :.:.:.::||
Frog   412 QQHQTITS--------------SHDPNSGAVA-----------------------SYNFSSAKGS 439

  Fly   456 TAVNAALKPRRGLTKNLLPYSVTPPRPAGPTEAQRKIEELTRQLEEEIEQSEEHGEYFGICHTCG 520
            ..|:          :..|||.|||.|.:||::|:|::|.||.:||:|:|...:. ||||||..||
Frog   440 ATVH----------RFKLPYQVTPSRESGPSQAERRLEALTLELEKELELHMKK-EYFGICIKCG 493

  Fly   521 EKVKGAGQACQAMGNLYHTNCFICCSCGRALRGKAFYNVHGRVYCEEDYMYSGFQQTAEKCAICG 585
            :.|.||.|||||||||||||||.||||||.|||||||||:|:||||||::||||||||:||.:||
Frog   494 KGVYGASQACQAMGNLYHTNCFTCCSCGRRLRGKAFYNVNGKVYCEEDFLYSGFQQTADKCFVCG 558

  Fly   586 HLIMEMILQAMGKSYHPGCFRCCVCNECLDGVPFTVDVDHKIYCVNDYHRMFAPKCASCGKGITP 650
            ||||||||||:|||||||||||.|||||||||||||||::.||||.|||.:||||||||.:.|.|
Frog   559 HLIMEMILQALGKSYHPGCFRCVVCNECLDGVPFTVDVENNIYCVKDYHTVFAPKCASCNQPILP 623

  Fly   651 VEGTDETVRVVSMDKDFHVDCYICEECGMQLTDEPDKRCYPLDGRLLCRGCHLQRLALQSSPHAR 715
            .:|::||:||||||||:||:||.||:|.:||.||..:|||||:|.|||..||::|:::...||..
Frog   624 AQGSEETIRVVSMDKDYHVECYHCEDCQLQLNDEEGRRCYPLEGHLLCHSCHIRRISVNVPPHQP 688

  Fly   716 HQEPV 720
            ...|:
Frog   689 PSYPM 693

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
jub	NP_572930.3	LIM1_Ajuba_like	516..569	CDD:188738	42/52 (81%)
		LIM2_Ajuba_like	581..633	CDD:188741	43/51 (84%)
		LIM3_Ajuba_like	641..702	CDD:188822	37/60 (62%)
wtip	XP_002935833.2	PHA03307	<197..>323	CDD:223039	34/162 (21%)
		LIM1_Ajuba_like	489..542	CDD:188738	42/52 (81%)
		LIM2_Ajuba_like	554..606	CDD:188741	43/51 (84%)
		LIM3_Ajuba_like	614..675	CDD:188822	37/60 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	112	1.000	Domainoid score	I6129
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004196
OrthoInspector	1	1.000	-	-		otm48518
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3625
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.000