DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nup93-1 and AT3G57350

DIOPT Version :9

Sequence 1:	NP_572929.1	Gene:	Nup93-1 / 32350	FlyBaseID:	FBgn0027537	Length:	823	Species:	Drosophila melanogaster
Sequence 2:	NP_191294.5	Gene:	AT3G57350 / 824902	AraportID:	AT3G57350	Length:	860	Species:	Arabidopsis thaliana

Alignment Length:	908	Identity:	184/908 - (20%)
Similarity:	343/908 - (37%)	Gaps:	219/908 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ELLKQAQRLTNETNTDTEVPGVERTMSQVLQATKEFHSRV--TQMGTNDLQAHILLGSKGVDLPK 67
            :||..:.:|..:....::.|.::|.:.|:...:::..::.  .:..:..:.|..||..:|::..:
plant    12 DLLHSSTKLLEQAAPSSQFPPLQRNLDQLEALSRKLKAKTLRNEAPSQSIAATRLLAREGINADQ 76

  Fly    68 LTQKLESLSARQTFEPIDPVTETNVQAYLKNERENAILSVIDETNRSIFKSVERQKWRCIYSEWG 132
            |::.|:|...:.|||.:.|...|:|:.||:...|.|::|.|.|..:...:|......:.:..:..
plant    77 LSRDLKSFELKTTFEDVFPAETTSVEEYLQQVHEMAMVSAIQEAQKDNVRSFNNYMLKVLEEDCI 141

  Fly   133 EEKEALLNAL-------------------------VGPNQQDFPDVQFQIVPTAMADEPTPYSQL 172
            :||...|::|                         :.|.....|..:.    .:|.::|.
plant   142 KEKRDFLHSLSKTSMLPKTKMINSSRGSHAGSLVPLSPQVSSKPGTEL----VSMTNKPI----- 197

  Fly   173 NGHEQ---MYAEQIAIHNQSIILGRRPNLLSTLAHVVQDSFNDE-------SVAEMWNVLQFMTA 227
              ||:   :|||.:...|.:...| .|..|:||.:...:|...:       ::.::|.::|.||.
plant   198 --HEKKAYVYAEVVKKLNSARERG-LPFKLATLFNGAYESLEIDLTRGKSVNMQKLWQLIQGMTG 259

  Fly   228 LPPVSSTIDPIKNRQTSPQFVEQARTYLERRYRTYMRKFIVANLAKARRGGIPSVYHMVRSYVGV 292
              ..|:....:..|..   .|..||.:||..:..::...|.::..:|..||.......:|:::.:
plant   260 --EESAVQHGVSKRMA---LVIGARRHLECGHGKHIMDTIQSHPTQAALGGSVGNLQRIRAFLRI 319

  Fly   293 TLQGQRALYGLHDVNN----GQP----LWPHVYYSLRSGDMDAA------------------ALY 331
            .|:.    ||..|.::    .||    .|..:|:.||:|..:.|                  ..:
plant   320 RLRD----YGSLDFDSVDARRQPPVDTTWQQIYFCLRTGYYEEAREIAQSSRSSQQQFAPLLTEW 380

  Fly   332 LKESGT------------CPDLLTLLTLRKNGDRDNLMVKLEGQLKLEYNSRLRACTDPYKKAVY 384
            :...||            |..||.:      |||       .||          ...|..|..:|
plant   381 ITTGGTVAAQTAATASEECEKLLRM------GDR-------FGQ----------TTYDKKKLLLY 422

  Fly   385 VVLLACDPHFTHV-----ELMRSIDDFLWMQLSILRRSDQSDSNTEQLTFSGL--QSL-----IL 437
            .::.........:     .|..:|:||||.:||.:|  |.:..::..:...||  .||     .|
plant   423 TIISGSRRQIDRIMRDFSTLFNTIEDFLWFKLSCVR--DVAGGSSSMIVNDGLVPYSLDDLQAYL 485

  Fly   438 EKYGENYFNAREKAAL-YFQVLTLTGQFEAAIEFL---ARTEKNRTHAIHMAIALNEISML---- 494
            .|:..:|:....|..| |..||.|:.|...||..:   |..|.....|:|:||:|.:.|:|
plant   486 NKFEPSYYTKNGKDPLVYPYVLLLSIQLLPAIMHMSNEAGDEGYNIDAVHVAISLVDHSILSEGS 550

  Fly   495 GTPRSVEQSLLSSDPDDPKPMKRLNLVRLIVMYTKCFERTDTTQALHYYYLLR-----NFKSENG 554
            ||.|.:  |::.::.:....:::...:.|        ...|....|.||....     ..::.:|
plant   551 GTGRKL--SVMDANAEASSMIRQYGSMYL--------HHGDLQMTLEYYAQAAIAVGGGQQAWSG 605

  Fly   555 RGNVMLTCVCDLLVEKCDDEMLELIFGTEDKKN---GLRYGG-------------IYAEFQIHEC 603
            |.||......:|:::    ::|..|...||..:   |.|..|             :..:|.|...
plant   606 RSNVDQQRQRNLMLK----QLLTEILSQEDGIHFLLGARGSGEEGELGRFLPDIKLRQQFLIEAA 666

  Fly   604 DKYSLAEMVGDELSKRGDYELAIELYFIGGQLDKALRLVNSLLAQVVHQPTQ---NGSVRNR--- 662
            .::..|          |.|:.:|||....|....||..:|..|::.:....:   :|..|..
plant   667 HQFQEA----------GLYDKSIELQKRVGAFSSALETINKCLSEAICSLVRGRPDGESRTEGLV 721

  Fly   663 --LGDIINRL---------DAALVVRKSDV--EVQVVVTYTVLTKVMKFFDHYHEGALRSALEIL 714
              ..||:|..         :..||:.:..:  |::.:::...|.::.|..|...|.|....|
plant   722 LSGNDILNSYKYHPDVSAQERHLVMEQETILRELEAILSIHKLARLNKHLDAIREVAKLPFL--- 783

  Fly   715 TNNHLIP----ASSLEVDECVTNIKRMGPEVIKVLPDILLASMDIVYQEYVKLMDSNETASGF 773
               ||.|    .:|.|..:..:..:...|:::||    .|..:|.|......:.......:||
plant   784 ---HLDPRQPDTTSDEFQKASSYFQTCVPDLLKV----ALTCLDNVADTDGSIRGMRSKIAGF 839

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nup93-1	NP_572929.1	Nic96	215..808	CDD:309288	137/661 (21%)
AT3G57350	NP_191294.5	Nic96	246..849	CDD:282017	137/662 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	62	1.000	Domainoid score	I3753
eggNOG	1	0.900	-	-		E1_KOG2168
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	91	1.000	Inparanoid score	I2268
OMA	1	1.010	-	-		QHG59183
OrthoDB	1	1.010	-	-		D187731at2759
OrthoFinder	1	1.000	-	-		FOG0002723
OrthoInspector	1	1.000	-	-		mtm1019
orthoMCL	1	0.900	-	-		OOG6_103333
Panther	1	1.100	-	-	O	PTHR11225
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840