DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Nup93-1 and AT2G41620

DIOPT Version :9

Sequence 1:	NP_572929.1	Gene:	Nup93-1 / 32350	FlyBaseID:	FBgn0027537	Length:	823	Species:	Drosophila melanogaster
Sequence 2:	NP_565951.1	Gene:	AT2G41620 / 818760	AraportID:	AT2G41620	Length:	861	Species:	Arabidopsis thaliana

Alignment Length:	947	Identity:	180/947 - (19%)
Similarity:	355/947 - (37%)	Gaps:	233/947 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 ELLKQAQRLTNETNTDTEVPGVERTMSQVLQATKEFHSRV--TQMGTNDLQAHILLGSKGVDLPK 67
            :||..:.:|..:....::.|.::|.:.|:...:|:..::.  .:..:..:.|..||..:|::..:
plant    12 DLLHSSSKLLEQAAPSSQFPPLQRNLDQLEALSKKLKAKTLRNEAPSQSIAATRLLAREGINAEQ 76

  Fly    68 LTQKLESLSARQTFEPIDPVTETNVQAYLKNERENAILSVIDETNRSIFKSVERQKWRCIYSEWG 132
            |.:.|:|...:.|||.:.|...|:|:.||:...|.|::|.|.|..:...:|......:.:..:|.
plant    77 LARDLKSFELKTTFEDVFPAEATSVEEYLQQVHEMAMVSAIQEAQKDNVRSFNDYMMKVLEEDWR 141

  Fly   133 EEKEALLNALVGPNQQDFPDVQF----------QIVPTAMADEPTPYSQLNGHEQMYAEQIAIH- 186
            :||...|.:|...:.  .|....          |:||...:..   .|...|.|.:....|.||
plant   142 KEKRDFLQSLSRISM--LPKTNMIDTSREAHAGQLVPVGSSPR---VSSTPGKELVALANIPIHE 201

  Fly   187 NQSIILGRRPNLLSTL---------AHVVQDSFN----------DESVAEMWNVLQFMTALPPVS 232
            .::.:.|.....|:|.         |...:|:::          ..::.::|.::|.:|.  ..|
plant   202 KKAYVYGEVVKKLNTSRERGMPFRPAMCFKDAYDTLGAEVTRGKSVNMQKIWQLVQAITG--EDS 264

  Fly   233 STIDPIKNRQTSPQFVEQARTYLERRYRTYMRKFIVANLAKARRGGIPSVYHMVRSYVGVTLQGQ 297
            :....:..|..   ....||.:|:..:..::...|..:..:|..||.......:|:::.:.|:.
plant   265 AVRQGVSKRMA---LAIGARHHLQHGHEKFIMDTIQTHPTQAALGGSVGNLQRIRAFLRIRLRD- 325

  Fly   298 RALYGLHDVNN----GQP----LWPHVYYSLRSGDMDAAALYLKESGTCPDLLTLLT--LRKNGD 352
               ||:.|.::    .||    .|..:|:.||:|..:.|....:.:.:......|||  :..:|
plant   326 ---YGVLDFDSTDARRQPPVDTTWQQIYFCLRTGYYEEAREIARSTRSSQQFAPLLTEWITTDG- 386

  Fly   353 RDNLMVKLEG--------QLKLEYNSRL-RACTDPYKKAVYVVLLACDPHFTHV-----ELMRSI 403
                ||..|.        :..|....|| |...|..|..:|.::.........:     .|..:|
plant   387 ----MVAAESAAIASEECEKMLRMGDRLGRTAYDKKKLLLYTIISGSRRQIERILRDLSTLFNTI 447

  Fly   404 DDFLWMQLSILRRSDQSDSNTEQLTFSGLQ-------SLILEKYGENYFNAREKAAL-YFQVLTL 460
            :||||.:||.:|  |.:..::..:...||.       ...|.|:..:|:....|..| |..||.|
plant   448 EDFLWFKLSCIR--DVTGGSSSVVLNDGLAPYSLDDLQAYLNKFEPSYYTKNGKDPLVYPYVLLL 510

  Fly   461 TGQFEAAIEFLARTEKN---RTHAIHMAIALNEISML--GTPRSVEQSLLSSDPDDPKPMKRLNL 520
            :.|...||..|::...:   ...|:|:||:|.:.|:|  |:....:.|::.|:.:...
plant   511 SVQLLPAIMHLSKEAGDGGYNIDAVHIAISLVDHSVLSEGSGTGHKLSVMDSNAEASS------- 568

  Fly   521 VRLIVMYTKCF-ERTDTTQALHYYYLLR-----NFKSENGRGNVMLTCVCDLLVEKCDDEMLELI 579
              :|..|...| ...|....:.||....     ...:.:||.||......:|::::...|:|
plant   569 --MIRQYGSMFLHHGDLQMTVEYYAQAAATVGGGQLAWSGRSNVDQQRQRNLMLKQLLTEIL--- 628

  Fly   580 FGTEDKKNGLRYGGIY------------------------AEFQI---HECDKYSLAEMVGDELS 617
                     ||..|||                        .:|.:   |:|.:..|
plant   629 ---------LRERGIYFLLGARGSGEEGQLGRFFPDSRLRQQFLVEAAHQCQEAGL--------- 675

  Fly   618 KRGDYELAIELYFIGGQLDKALRLVNSLLAQVVHQPTQNGSVRNRLGDIINRLD-----AALVVR 677
                |:.:|||....|....||..:|..|::.:....:            .|||     :.|::.
plant   676 ----YDKSIELQKRVGAFSAALETINKCLSEAICSLAR------------GRLDGESRTSGLILA 724

  Fly   678 KSDVEVQVVVTYTVLTKVMKFFDHYHEGALRSALEILTNNHLIPASSLEVDECVTNIKRMG---- 738
            .:|              :::.:.:|.|.:|:....::....::  ..||....:..:.|:|
plant   725 GND--------------ILETYKYYPEVSLQERERVMEQETIL--RELEAILSIHKLGRLGNHLD 773

  Fly   739 --PEVIKV--------LPDILLASMDIVYQEYVKLMDSNETASGFFDES---------KCVNKEP 784
              .|:.|:        :||   |:.|:.           ::||.:|...         .|::..|
plant   774 ALREIAKLPFLHLDPRMPD---ATADVF-----------QSASPYFQTCVPDLLKVALTCLDNVP 824

  Fly   785 ----AVKHLRDRAKAFTNMAASVPYRMPSTTNQRLVQ 817
                :::.:|.:...|  :|::.....|....:::.:
plant   825 DTDGSIRAMRSKIAGF--LASNTHRNWPRDLYEKVAR 859

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nup93-1	NP_572929.1	Nic96	215..808	CDD:309288	131/694 (19%)
AT2G41620	NP_565951.1	Nic96	248..820	CDD:397976	126/663 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	62	1.000	Domainoid score	I3753
eggNOG	1	0.900	-	-		E1_KOG2168
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	91	1.000	Inparanoid score	I2268
OMA	1	1.010	-	-		QHG59183
OrthoDB	1	1.010	-	-		D187731at2759
OrthoFinder	1	1.000	-	-		FOG0002723
OrthoInspector	1	1.000	-	-		mtm1019
orthoMCL	1	0.900	-	-		OOG6_103333
Panther	1	1.100	-	-	O	PTHR11225
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.840