Protein Alignment Clic and Clic3

DIOPT Version :9

• Sequence 1: NP_001259537.2
• Gene: Clic / 32349
• FlyBaseID: FBgn0030529
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: XP_030107910.1
• Gene: Clic3 / 69454
• MGIID: 1916704
• Length: 268
• Species: Mus musculus
• Alignment Length: 220
• Identity: 57/220 - (25%)
• Similarity: 92/220 - (41%)
• Gaps: 24/220 - (10%)

  Fly    33 DGRRKGACLFCQEYFMDLYLLAELKTISLKVTTVDMQKPPPDFRTNFEATHPPILIDNGLAILEN 97
            ||...|.|..||..||.|.    ||.:...:||||.::.....:.....:..|||:.:|....:.
Mouse    47 DGESVGHCPSCQRLFMVLL----LKGVPFTLTTVDTRRALDVLKDFAPGSQLPILLYDGDVKTDT 107

  Fly    98 EKIERHIMKNI--PGGYNLFVQDKEVATLIENLYVKLKLMLVKKDEAKNNALL-----------S 149
            .:||..:.:.:  |...:|..:.:|..|...:::.|....:......::|||.           |
Mouse   108 LQIEEFLEETLGPPDFPSLAPRYRESNTAGNDIFHKFSAFIKNPVPTQDNALYQQLLRALTRLDS 172

  Fly   150 HLRKIND-------HLSARNTRFLTGDTMCCFDCELMPRLQHIRVAGKYFVDFEIPTHLTALWRY 207
            :||...|       ||...:.|||.||.....||.|:|:|..:.....:|....||..|:.:.||
Mouse   173 YLRAPLDHELAQEPHLRESHRRFLDGDQFTLADCSLLPKLHIVDTVCAHFRQLPIPAELSCVRRY 237

  Fly   208 MYHMYQLDAFTQSCPADQDIINHYK 232
            :....|...|..:||...:|:..|:
Mouse   238 LDSALQKKEFKYTCPHSAEILAAYQ 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Clic	NP_001259537.2	GST_N_CLIC	18..112	CDD:239359	22/80 (28%)
		O-ClC	21..231	CDD:129941	56/217 (26%)
		GST_C_CLIC	118..232	CDD:198307	33/131 (25%)
Clic3	XP_030107910.1	O-ClC	43..261	CDD:129941	56/217 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844738
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	121	1.000	Inparanoid score	I4746
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57946
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000394
OrthoInspector	1	1.000	-	-		otm43152
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43920
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.000