Protein Alignment Clic and clic5

DIOPT Version :10

• Sequence 1: NP_572928.1
• Gene: Clic / 32349
• FlyBaseID: FBgn0030529
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: XP_012825763.1
• Gene: clic5 / 448566
• XenbaseID: XB-GENE-945566
• Length: 384
• Species: Xenopus tropicalis
• Alignment Length: 248
• Identity: 74/248 - (29%)
• Similarity: 122/248 - (49%)
• Gaps: 35/248 - (14%)

  Fly     2 SEVESQQSQETNGSSKFDVPEIELIIKASTIDGRRKGACLFCQEYFMDLYLLAELKTISLKVTTV 66
            ::.|.....||      :.|:|.:.|||.: ||...|.|.|.|..||.|:    ||.:...||||
 Frog   135 TQYEDAVDNET------EEPDIAIYIKAGS-DGESIGNCPFSQRLFMILW----LKGVVFNVTTV 188

  Fly    67 DMQKPPPDFRTNFEATHPPILIDNGLAILENEKIERHIMKNI-PGGY-NLFVQDKEVATLIENLY 129
            |:::.|.|.......||||.|..||....:..|||..:.::: |..| .|..:.:|..|...:::
 Frog   189 DLKRKPADLHNLAPGTHPPFLTFNGEVKTDVNKIEEFLEESLAPPRYPKLAAKHRESNTAGIDIF 253

  Fly   130 VKLKLMLVKKDEAKNNA-----LLSHLRKINDHLSA-------RNTR---------FLTGDTMCC 173
            .|.. ..:|..:.::||     |...|:|::.:|::       .|:|         ||.||....
 Frog   254 SKFS-AYIKNTKQQDNAGLEKGLTKALKKLDTYLNSPLPEEIDANSREEEKVSKRKFLDGDEFTL 317

  Fly   174 FDCELMPRLQHIRVAGKYFVDFEIPTHLTALWRYMYHMYQLDAFTQSCPADQD 226
            .||.|:|:|..:::..|.:.::|||..::.:|||:.:.|..|.||.:|.||::
 Frog   318 ADCNLLPKLHVVKIVAKKYRNYEIPAEMSGIWRYLKNAYARDEFTNTCAADKE 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Clic	NP_572928.1	GST_N_CLIC	18..112	CDD:239359	34/94 (36%)
		GST_C_CLIC	118..232	CDD:198307	35/130 (27%)
clic5	XP_012825763.1	O-ClC	148..383	CDD:129941	71/229 (31%)