DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Clic and eEF1gamma

DIOPT Version :9

Sequence 1:	NP_001259537.2	Gene:	Clic / 32349	FlyBaseID:	FBgn0030529	Length:	260	Species:	Drosophila melanogaster
Sequence 2:	NP_001189308.1	Gene:	eEF1gamma / 44791	FlyBaseID:	FBgn0029176	Length:	431	Species:	Drosophila melanogaster

Alignment Length:	190	Identity:	38/190 - (20%)
Similarity:	75/190 - (39%)	Gaps:	42/190 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 FEATHPPILID-NGLA-ILENEKIERHIMKNIPGGYNLFVQ----------DKE-VATLIENLYV 130
            ||......|.: |.:| :|.||::.        ||...|||          |.| |......::.
  Fly    58 FETAEGQYLSESNAIAYLLANEQLR--------GGKCPFVQAQVQQWISFADNEIVPASCAWVFP 114

  Fly   131 KLKLMLVKKDEAKNNALLSHLRKINDHLSARNTRFLTGDTMCCFDCELMPRLQHIRVAGKYFVDF 195
            .|.::..:|:........:.|:::|..|  ::..||.|:.:...|..:...|.|:.   :|.::.
  Fly   115 LLGILPQQKNSTAKQEAEAVLQQLNQKL--QDATFLAGERITLADIVVFSSLLHLY---EYVLEP 174

  Fly   196 EIPTHLTALWRY---MYHMYQLDAFTQSCPADQDIINHYKLQQSLKM---KKHEELETPT 249
            .:.:....:.|:   :.:..|:.|          ::..|||.:...:   ||:.|.:..|
  Fly   175 SVRSAFGNVNRWFVTILNQKQVQA----------VVKDYKLCEKALVFDPKKYAEFQAKT 224

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Clic	NP_001259537.2	GST_N_CLIC	18..112	CDD:239359	9/34 (26%)
		O-ClC	21..231	CDD:129941	31/167 (19%)
		GST_C_CLIC	118..232	CDD:198307	18/117 (15%)
eEF1gamma	NP_001189308.1	GST_N_EF1Bgamma	4..79	CDD:239342	6/20 (30%)
		GstA	5..187	CDD:223698	29/141 (21%)
		GST_C_EF1Bgamma_like	90..209	CDD:198290	22/133 (17%)
		EF1G	271..376	CDD:279041
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45459959
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930