Protein Alignment Clic and clic2

DIOPT Version :9

• Sequence 1: NP_001259537.2
• Gene: Clic / 32349
• FlyBaseID: FBgn0030529
• Length: 260
• Species: Drosophila melanogaster
• Sequence 2: NP_001002561.2
• Gene: clic2 / 436834
• ZFINID: ZDB-GENE-040718-299
• Length: 239
• Species: Danio rerio
• Alignment Length: 229
• Identity: 78/229 - (34%)
• Similarity: 118/229 - (51%)
• Gaps: 25/229 - (10%)

  Fly    21 PEIELIIKASTIDGRRKGACLFCQEYFMDLYLLAELKTISLKVTTVDMQKPPPDFRTNFEATHPP 85
            |.|||.|||.. ||...|.|.|||..||.|:    ||.:...||||||:|.|.:.:.....|:||
Zfish    11 PRIELFIKAGH-DGENVGNCPFCQRLFMVLW----LKGVKFTVTTVDMRKKPDELKDLAPGTNPP 70

  Fly    86 ILIDNGLAILENEKIERHIMKNI-PGGY-NLFVQDKEVATLIENLYVKLKLMLVKKDEAKN---- 144
            .|:.||....:..|||..:...: |..| :|..:.||...:..:::.|....:  |:...|
Zfish    71 FLLYNGTLKTDFIKIEEFLETTLAPPRYPHLSPRYKESFDVGADIFAKFSAFI--KNSPNNAFHE 133

  Fly   145 NALLSHLRKINDHL------------SARNTRFLTGDTMCCFDCELMPRLQHIRVAGKYFVDFEI 197
            .|||...::::|:|            |....:||.|:.:...||.|:|:|..|:||.:.:.:|:|
Zfish   134 KALLREFKRLDDYLNTPLQDELDQNISVSKRKFLDGNRLTLADCNLLPKLHVIKVAARKYCNFDI 198

  Fly   198 PTHLTALWRYMYHMYQLDAFTQSCPADQDIINHY 231
            ||..|.:|||:...|:.:.|:|:||||.:|...|
Zfish   199 PTQFTGVWRYLQSAYEREEFSQTCPADIEIEKAY 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Clic	NP_001259537.2	GST_N_CLIC	18..112	CDD:239359	37/91 (41%)
		O-ClC	21..231	CDD:129941	77/227 (34%)
		GST_C_CLIC	118..232	CDD:198307	39/130 (30%)
clic2	NP_001002561.2	O-ClC	11..238	CDD:129941	78/229 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589576
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	120	1.000	Inparanoid score	I4748
OMA	1	1.010	-	-		QHG57946
OrthoDB	1	1.010	-	-		D541338at33208
OrthoFinder	1	1.000	-	-		FOG0000394
OrthoInspector	1	1.000	-	-		otm24777
orthoMCL	1	0.900	-	-		OOG6_107975
Panther	1	1.100	-	-	O	PTHR43920
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2518
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.940