DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11095 and NUDT8

DIOPT Version :9

Sequence 1:	NP_572927.1	Gene:	CG11095 / 32348	FlyBaseID:	FBgn0030528	Length:	283	Species:	Drosophila melanogaster
Sequence 2:	NP_001230679.1	Gene:	NUDT8 / 254552	HGNCID:	8055	Length:	236	Species:	Homo sapiens

Alignment Length:	212	Identity:	74/212 - (34%)
Similarity:	104/212 - (49%)	Gaps:	29/212 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 LGPESQRRCME-------KMRSLPAFPRPKALTPSRREKQTSAVLIALCQERGTNEISLLYTRRS 107
            |..|.:.||..       ::|:.||               ::|||:.||..||..  :||||.||
Human     6 LSAEGELRCRRLLAGATARLRARPA---------------SAAVLVPLCSVRGVP--ALLYTLRS 53

  Fly   108 RHLRS-HSFQISFPGGRRDDHDSSYVDCALRETEEEIGLPRHRIQVWGEAKQLQLPRTSSIVPVV 171
            ..|.. |...:|||||:.|..|...|..|||||.||:||......|||..:.:..|:.:::|||:
Human    54 SRLTGRHKGDVSFPGGKCDPADQDVVHTALRETREELGLAVPEEHVWGLLRPVYDPQKATVVPVL 118

  Fly   172 GVVPDFSLSELRLNWEEVEEAFSVPLTSLMLPKATRHTQFRSG----YSGPVFVVDHYRIWGITG 232
            ..|.......||.|.|||:|.|::||..|:..:...:|.|..|    |:.|||:...:|:||:|.
Human   119 AGVGPLDPQSLRPNSEEVDEVFALPLAHLLQTQNQGYTHFCRGGHFRYTLPVFLHGPHRVWGLTA 183

  Fly   233 YLTHLFLHCLLPPNLLP 249
            .:|...|..|.|....|
Human   184 VITEFALQLLAPGTYQP 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11095	NP_572927.1	CoAse	84..238	CDD:239518	63/158 (40%)
NUDT8	NP_001230679.1	CoAse	32..186	CDD:239518	62/155 (40%)
NUDT8	NP_001230679.1	Nudix box	70..91		10/20 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	86	1.000	Domainoid score	I8114
eggNOG	1	0.900	-	-		E1_COG0494
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41633
Inparanoid	1	1.050	112	1.000	Inparanoid score	I4867
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52532
OrthoDB	1	1.010	-	-		D1253012at2759
OrthoFinder	1	1.000	-	-		FOG0001407
OrthoInspector	1	1.000	-	-		oto90376
orthoMCL	1	0.900	-	-		OOG6_101045
Panther	1	1.100	-	-	LDO	PTHR12992
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1771
SonicParanoid	1	1.000	-	-		X6507
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.870