DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10993 and Abt1

DIOPT Version :9

Sequence 1:	NP_572923.1	Gene:	CG10993 / 32344	FlyBaseID:	FBgn0030524	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	NP_001020845.1	Gene:	Abt1 / 306960	RGDID:	1310785	Length:	268	Species:	Rattus norvegicus

Alignment Length:	197	Identity:	57/197 - (28%)
Similarity:	98/197 - (49%)	Gaps:	42/197 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 VEESEPEMPFSYKTQPDEGESVNGEAHTSDDGDEMELATFKAASKK---GVIYISNLPKHMTLTR 80
            |||.:..|        :|.:.||.||  :::.:|.|.|:...:.||   |::|:.::|.......
  Rat     8 VEEQKAAM--------EEEKEVNAEA--AEELEEAEEASCNGSKKKVVPGIVYLGHVPPRFRPLH 62

  Fly    81 LREILGEYGAIGRAFLRSQK--LSRK-------------PHNFLFAEGWVEFKSKRVAKQIVPLL 130
            :|.:|..||.:||.|.:::.  :.||             .::..:.||||||:.||:||::...|
  Rat    63 VRNLLSVYGEVGRVFFQAEDPFVRRKKKAAAAAGGKKGAKYSKDYTEGWVEFRDKRIAKRVAASL 127

  Fly   131 NYKQISTHKKSPFYYSLWIMEYLPRFKWARLNELMNIVPVTNSQNHLKFLN--KKAKKAKKVKKA 193
            :...:...|:|||.|.||.::||.||.|:.|:|            ||.|..  ::.:...:|.:|
  Rat   128 HNTPMGARKRSPFRYDLWNLKYLHRFTWSHLSE------------HLAFERQVRRQRLRAEVAQA 180

  Fly   194 KK 195
            |:
  Rat   181 KR 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10993	NP_572923.1	RRM_ABT1_like	65..154	CDD:240709	31/103 (30%)
Abt1	NP_001020845.1	RRM_ABT1_like	47..151	CDD:240709	31/103 (30%)
Abt1	NP_001020845.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	200..242
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340514
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3152
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	130	1.000	Inparanoid score	I4546
OMA	1	1.010	-	-		QHG56381
OrthoDB	1	1.010	-	-		D1377351at2759
OrthoFinder	1	1.000	-	-		FOG0002458
OrthoInspector	1	1.000	-	-		otm45062
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12311
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1640
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.870