DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10993 and F57B10.8

DIOPT Version :9

Sequence 1:	NP_572923.1	Gene:	CG10993 / 32344	FlyBaseID:	FBgn0030524	Length:	210	Species:	Drosophila melanogaster
Sequence 2:	NP_491887.1	Gene:	F57B10.8 / 172368	WormBaseID:	WBGene00019005	Length:	268	Species:	Caenorhabditis elegans

Alignment Length:	249	Identity:	73/249 - (29%)
Similarity:	106/249 - (42%)	Gaps:	62/249 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KKKSKPKRKPTR-------MEVEESEPEM----PFSYKTQPDEGESVN---GEAHTSDDGDEMEL 55
            |||.|..||..:       |::|| |.||    ..|.:|..:|.|:.|   .|..|.:..|: |:
Worm     6 KKKKKIVRKSIKKPVVEEDMKMEE-EKEMLEPKEESIETDNNEDEAGNLDDSEIKTEESEDD-EM 68

  Fly    56 ATFKAASKK----GVIYISNLPKHMTLTRLREILGEY--GAIGRAFLRSQKLSRKPHNFLFAEGW 114
            .||:...:|    ||::.|.:|....:.|:||...:.  |.:||.||...|.|:.| .:|::|||
Worm    69 ETFEDPEQKQKKTGVVFFSTIPPKYNVVRMREYFEKRCPGQVGRIFLARNKHSKNP-QYLYSEGW 132

  Fly   115 VEFKSKRVAKQIVPLLNYKQISTHKKSPFYYSLWIMEYLPRFKWARLNELMNI----------VP 169
            :|.|.|::||.|...::...|....|.|....||.:.||..|||..|.|.:..          |.
Worm   133 MELKKKKIAKAIAEQIDNTPIGGKNKDPVSSMLWNIRYLSGFKWVHLMEQLQYEKEVEKRRMNVE 197

  Fly   170 VTNSQ-------------NHLKFLNKKA----------------KKAKKVKKAK 194
            |..::             .||:.|..|.                ||..||||.:
Worm   198 VAQARRIAAHFEEQIEKGKHLRKLEAKVTASGGKWDKFQRDVQQKKVVKVKKER 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10993	NP_572923.1	RRM_ABT1_like	65..154	CDD:240709	31/90 (34%)
F57B10.8	NP_491887.1	RRM_SF	82..172	CDD:302621	31/90 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159071
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3152
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I3295
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56381
OrthoDB	1	1.010	-	-		D1377351at2759
OrthoFinder	1	1.000	-	-		FOG0002458
OrthoInspector	1	1.000	-	-		otm14709
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12311
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R417
SonicParanoid	1	1.000	-	-		X1640
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.900