Protein Alignment inaE and dagla

DIOPT Version :10

• Sequence 1: NP_001138195.1
• Gene: inaE / 32343
• FlyBaseID: FBgn0261244
• Length: 1318
• Species: Drosophila melanogaster
• Sequence 2: XP_004913465.1
• Gene: dagla / 100498478
• XenbaseID: XB-GENE-6037909
• Length: 1032
• Species: Xenopus tropicalis
• Alignment Length: 1118
• Identity: 384/1118 - (34%)
• Similarity: 562/1118 - (50%)
• Gaps: 153/1118 - (13%)

  Fly     1 MPGLVVFRRRWSVGSDDLVVPGAFLLTIHFICFVIVSVSLVIFEYNTRILSVKLLFYHLIGYLLI 65
            |||:|||||||||||||||:||.||..:|...|||:||.|....||........|..|..|||.|
 Frog     1 MPGIVVFRRRWSVGSDDLVLPGIFLFVLHSTWFVILSVVLFGLTYNPHETCSLNLVDHGRGYLGI 65

  Fly    66 LFFSICVEIGICVISMRGSILDAEARTSINIWIYLKSLVILFDIAWLAVGSVWLGHYYTTAPIDD 130
            |...:..|:.|..:||||.||..|.|.|:...:|::..:::.:..:..||.|||..|||:.....
 Frog    66 LLSCMIAEMAIIWLSMRGGILYTEPRDSMQYVLYVRLAILVIEFIYAIVGIVWLAQYYTSCNDVT 130

  Fly   131 PKKVYIAIIICNWALVVITLITIWCTFDAAGRSWVKMKKYQRSMRETESRFNYKRSNSMNRNWRQ 195
            .|.|.:.:::|||.:::...||:.|.||..||::||::..:|..|           |....|.|.
 Frog   131 AKNVTLGMVVCNWVVILSVCITVLCVFDPTGRTFVKLRATKRRQR-----------NLRTYNLRH 184

  Fly   196 RKVMRAYQDSWDHRCRLLFCCMGSSERNRNSFTDIARLLSDFFRELDVVPSDVVAGLVLLRKFQR 260
            | :......||..|.::..||..:.:...:::::||.|.::|||:||:||||::|||||||:.||
 Frog   185 R-LEEGQASSWTRRLKVFLCCTRTKDSQSDAYSEIAYLFAEFFRDLDIVPSDIIAGLVLLRQRQR 248

  Fly   261 LEREAIVRQRKNGTYEFLSGVPITERTQFLALNDAKNYDFFQTVIHYMYFAQGAYGWPMYVIINR 325
            .:|.|::.:..|....||||:|:|.:|::|.|.:|:....::.|.:||.||..|||||||:|.|
 Frog   249 AKRNAVLDEANNDILAFLSGMPVTRKTKYLDLKNAQEMQRYKEVCYYMLFALAAYGWPMYLIRN- 312

  Fly   326 SKMWHLVPEL-------KCFGCCCGTS------DDTEVIQDNCCLCNYAALKKTL---QLGDIDI 374
                   |..       .|..|||..|      ....:.:||||.||..|:|:..   .:..:||
 Frog   313 -------PTCGICRLAGACSSCCCLCSARPRFAPGVTIEEDNCCGCNAIAIKRHFLDENMNMVDI 370

  Fly   375 VYATYHVDVGETPFFVAIDYTHRAVVISIRGTLSMKDILTDLNAEGEVLPLQPPRDDWLGHKGMV 439
            ||.:.|..|.|||||||:|:..:.||||||||||.||.||||..:.|.||::.....||||||||
 Frog   371 VYTSCHDAVYETPFFVAVDHDKKKVVISIRGTLSPKDALTDLTGDAERLPVEGHHGTWLGHKGMV 435

  Fly   440 QAAIYIRNKLQEENLIERALQRNPDRQTHTFDLVLVGHSLGAGTAAILAILLKPEHPTLQCFSYS 504
            .:|.||:.||::|.::.:|..|:..|.|..::|::|||||||||||||:.||:|::|:|:||:||
 Frog   436 LSAEYIKKKLEQEMVLSQAFGRDLARGTKHYELIVVGHSLGAGTAAILSFLLRPQYPSLKCFAYS 500

  Fly   505 PPGGLLSMPAVEYSKSFITSVVLGKDVVPRIGLNQMEALRADLINAIQRSVDPKWKTISCSVICC 569
            |||||||..|:||||.|:||||||||:||||||:|:|..|..|::.:|||..|||:.|.....|.
 Frog   501 PPGGLLSEDAMEYSKEFVTSVVLGKDLVPRIGLSQLEGFRRHLLDVLQRSNKPKWRIILGGTKCI 565

  Fly   570 GCG--PEPTSVVNMSGQDTHINQYQEERGTARSTSAHPTDSSIALTLHQPLYPPGRIIHIVRHHP 632
            ...  ||.:..:.:               .:.....||:|.:|||:...||||||||||:|.:||
 Frog   566 PKSELPEESEAITI---------------PSNRLWTHPSDLTIALSASTPLYPPGRIIHVVHNHP 615

  Fly   633 KPDEQKYDSGWRNVLKNREPVYQAIWADSTDFDEVLISPVMLQDHMPDKVLAALKKVVTTSGPRK 697
            .  ||  ...|    ...||.|.|||.|:..|:||:|||.||.:|:|..|:..|.||:
 Frog   616 V--EQ--CCFW----NQEEPTYFAIWGDNKAFEEVIISPAMLHEHLPHVVMEGLNKVL------- 665

  Fly   698 PQRQTSNAFSTGSNEAAH------DMDLEP-------PHCSGHSAPTDAMRFETRTDPG--QMQN 747
               :..|...|....||.      ::||.|       ||     .|...:.......||  ..:|
 Frog   666 ---ENYNKGKTALLSAAKVMVSPTEVDLNPELIFQQQPH-----PPPPILEVIPAIMPGAHNRRN 722

  Fly   748 SMSQSQHCKRLSQSSYTNLSNCLVLTPTAQH---------KLCLETSFTNGSTPHQSGVQPNPRL 803
            |.::|:.    |..|.....:..:|:|..:.         |.||..|..:...|
 Frog   723 SSTKSKQ----SDISLEGFYDSRLLSPILKDPVELLLMSTKDCLAVSLQDRRAP----------- 772

  Fly   804 TSAASSLLSSATTPYDISSALDDSLATVALRQSPSL---ISAETTATVIVNPEPDAEEIAIPQRL 865
             .|....||...:.|...|.......::  |.||||   :..:.:....::|....|..::..|.
 Frog   773 -LATMESLSDNESVYSFDSRRSSGFRSI--RGSPSLRAVLERDESHCFFIDPTIPEENPSLSSRT 834

  Fly   866 KAVAFDMALTPPPTLPERSMLGRQHSEKKPRSLPLAQVQALRRASDAGAV-PGVDLLHDDWYGLA 929
            :.:..| ||:......:.:.:........|..||....:||.....:.|: |..:.|......|.
 Frog   835 ELLGAD-ALSKHSQESQPTEVAHNSGRSSPGDLPPWDEEALAGVESSRALTPAKEELALQNGRLN 898

  Fly   930 PLASPETLSEISSVSSRTSVPISLANSIERYLQHMGVGVGGPKVPLEDIFESQLHTPKVMRRAPK 994
            .:.||:.|.....:.|..::. :.:.|::. |.|:.|..|..:    ||.:| :...:::.|| |
 Frog   899 EVPSPQVLEFAEFIDSLFNLD-NKSGSLQD-LYHVMVSDGTDR----DIPKS-VSDQEILLRA-K 955

  Fly   995 FSENLAGCAEDTRNLDQYKRLGRVFITFPRIFPDQSPAAHSLDSSDDSFESASAHSLQRLQLPHG 1059
            |..||....                   ||:|...:..:..: |...||..:|:..|..| .|.|
 Frog   956 FEPNLVPKP-------------------PRLFAGSADPSSGI-SVSASFPLSSSGELMDL-TPTG 999

  Fly  1060 ANAVQSSKSADPL 1072
            .:: |...:.||:
 Frog  1000 MSS-QECLTPDPI 1011

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
inaE	NP_001138195.1	Lipase_3	300..542	CDD:238287	130/257 (51%)
dagla	XP_004913465.1	Lipase_3	288..546	CDD:238287	133/265 (50%)