DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11103 and tm2d2

DIOPT Version :9

Sequence 1:	NP_001033842.2	Gene:	CG11103 / 32342	FlyBaseID:	FBgn0030522	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	NP_001002640.1	Gene:	tm2d2 / 436913	ZFINID:	ZDB-GENE-040718-387	Length:	229	Species:	Danio rerio

Alignment Length:	218	Identity:	102/218 - (46%)
Similarity:	129/218 - (59%)	Gaps:	12/218 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LLAFLVARQHDAQAIQARSDKEQPQTVVSGTAVQSVVPVQAQLGSGMGPSSSSSSAS----SASG 67
            ||.|.|......:.|.:::..|.|     |..|.:..||   |.|.....:.:.|.|    ..|.
Zfish    16 LLFFTVLLLQCLEGIHSQNSTEPP-----GNRVTTSKPV---LFSEQPEENVTESGSVIPTETSN 72

  Fly    68 GAGNSAFYPLGPNVMCSFLPRDFLDCKDPVDHRENATAQQEKKYGCLKFGGSTYEEVEHAMVWCT 132
            ......:.|..|.|:|.:||.:|:.|:|||||..|.:|.||..|||:||||..|::|.|..|.||
Zfish    73 HTEQYEYNPPSPVVLCRYLPEEFIFCQDPVDHGGNVSAFQELGYGCVKFGGQVYKDVNHTQVLCT 137

  Fly   133 VFADIECYGNRTFLRAGVPCVRYTDHYFVTTLIYSMLLGFLGMDRFCLGQTGTAVGKLLTMGGVG 197
            ....|||.|.|.|||...||::||.|||:|||:||..||..|:||||||.||||||||||:||:|
Zfish   138 ALDGIECAGPREFLRGNEPCIKYTGHYFITTLLYSFFLGCFGVDRFCLGHTGTAVGKLLTLGGLG 202

  Fly   198 VWWIIDVILLITNNLLPEDGSNW 220
            :||.:|:|||||..|.|.|.|||
Zfish   203 IWWFVDLILLITGGLTPSDSSNW 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11103	NP_001033842.2	TM2	156..205	CDD:377473	34/48 (71%)
tm2d2	NP_001002640.1	TM2	161..210	CDD:282945	34/48 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573537
Domainoid	1	1.000	101	1.000	Domainoid score	I6945
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12328
Inparanoid	1	1.050	201	1.000	Inparanoid score	I3730
OMA	1	1.010	-	-		QHG57548
OrthoDB	1	1.010	-	-		D1278556at2759
OrthoFinder	1	1.000	-	-		FOG0007509
OrthoInspector	1	1.000	-	-		oto39126
orthoMCL	1	0.900	-	-		OOG6_107239
Panther	1	1.100	-	-	LDO	PTHR21016
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2846
SonicParanoid	1	1.000	-	-		X5640
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940