DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CtsB1 and AT1G29080

DIOPT Version :9

Sequence 1:	NP_001259536.2	Gene:	CtsB1 / 32341	FlyBaseID:	FBgn0030521	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_564320.1	Gene:	AT1G29080 / 839783	AraportID:	AT1G29080	Length:	346	Species:	Arabidopsis thaliana

Alignment Length:	245	Identity:	66/245 - (26%)
Similarity:	98/245 - (40%)	Gaps:	47/245 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 SRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDLVSCCHTCGFGCN 157
            :.|.|.|...:..::.||.||.||||.|:.|:.....|..|..::  .|...|:.|......||.
plant   132 TNKDWRNEGAVTPVKSQGECGGCWAFSAIAAVEGLTKIARGNLIS--LSEQQLLDCTREQNNGCK 194

  Fly   158 GGFPGAAWSYWTR-KGIVSGGPYGSNQGCRPYEI--SPCEHHVNGTRPPCAHGGRTPKCSHVCQS 219
            ||....|::|..: :||.|...|       ||::  .||.   :..||.            :...
plant   195 GGTFVNAFNYIIKHRGISSENEY-------PYQVKEGPCR---SNARPA------------ILIR 237

  Fly   220 GYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVEGAFTVYE-DLILYKDGVYQHEHGKELGG 283
            |:.              :|..|......|.::..||..|....| ..:.|..|||...:......
plant   238 GFE--------------NVPSNNERALLEAVSRQPVAVAIDASEAGFVHYSGGVYNARNCGTSVN 288

  Fly   284 HAIRILGWGVWGEEKIPYWLIGNSWNTDWGDHGFFRILRG----QDHCGI 329
            ||:.::|:|. ..|.:.|||..|||...||::|:.||.|.    |..||:
plant   289 HAVTLVGYGT-SPEGMKYWLAKNSWGKTWGENGYIRIRRDVEWPQGMCGV 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358
CtsB1	NP_001259536.2	Peptidase_C1A_CathepsinB	88..336	CDD:239111	66/245 (27%)
AT1G29080	NP_564320.1	PTZ00203	4..328	CDD:185513	63/234 (27%)
		Inhibitor_I29	39..95	CDD:214853
		Peptidase_C1	135..345	CDD:278538	65/242 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820