DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CtsB1 and AT3G43960

DIOPT Version :9

Sequence 1:	NP_001259536.2	Gene:	CtsB1 / 32341	FlyBaseID:	FBgn0030521	Length:	340	Species:	Drosophila melanogaster
Sequence 2:	NP_566867.1	Gene:	AT3G43960 / 823513	AraportID:	AT3G43960	Length:	376	Species:	Arabidopsis thaliana

Alignment Length:	249	Identity:	74/249 - (29%)
Similarity:	110/249 - (44%)	Gaps:	57/249 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    85 DELPEEFDSRKQWPNCPTIGEIRDQGSCGSCWAF---GAVEAMSDRVCIHSGGKVNFHFSADDLV 146
            |.||:|.|.|::....|   .::.||.|||||||   ||||.::.   |.:|..|:  .|..:|:
plant   125 DVLPDEVDWRERGAVVP---RVKRQGECGSCWAFAATGAVEGINQ---ITTGELVS--LSEQELI 181

  Fly   147 SCCH-TCGFGCNGGFPGAAWSYWTRK---GIVSGGPYG----SNQGCRPYEISPCEHHVNGTRPP 203
            .|.. ...|||.||  ||.|::...|   ||||...||    ....|:..|:
plant   182 DCDRGNDNFGCAGG--GAVWAFEFIKENGGIVSDEVYGYTGEDTAACKAIEM------------- 231

  Fly   204 CAHGGRTPKCSHVCQSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVEGAFTVYEDLILY 268
                 :|.:.  |..:|:.|....|:      .|:::.|......:|.:.         .::..|
plant   232 -----KTTRV--VTINGHEVVPVNDE------MSLKKAVAYQPISVMISA---------ANMSDY 274

  Fly   269 KDGVYQHEHGKELGGHAIRILGWGVWGEEKIPYWLIGNSWNTDWGDHGFFRILR 322
            |.|||:.......|.|.:.|:|:|...:|. .||||.|||..:||:.|:.|:.|
plant   275 KSGVYKGACSNLWGDHNVLIVGYGTSSDEG-DYWLIRNSWGPEWGEGGYLRLQR 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358
CtsB1	NP_001259536.2	Peptidase_C1A_CathepsinB	88..336	CDD:239111	72/246 (29%)
AT3G43960	NP_566867.1	Inhibitor_I29	41..97	CDD:214853
AT3G43960	NP_566867.1	Peptidase_C1	127..346	CDD:278538	73/247 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820