Protein Alignment CtsB1 and Cts8

DIOPT Version :9

• Sequence 1: NP_001259536.2
• Gene: CtsB1 / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001121688.1
• Gene: Cts8 / 680718
• RGDID: 1588248
• Length: 333
• Species: Rattus norvegicus
• Alignment Length: 325
• Identity: 80/325 - (24%)
• Similarity: 136/325 - (41%)
• Gaps: 60/325 - (18%)

  Fly    19 GEPSLLSDEFIEVVR-------SKAKTWTVGRNFDASVTEGHIRRLMGVHPDAHKFALPDKREVL 76
            |:...:.:|.::||:       .:.|.:|:..|..|.:|....|::|...|..:   |..|:.:.
  Rat    46 GQKRAVWEENMKVVKQHNIEYDQEKKNFTMELNAFADMTGEEFRKMMTNIPVQN---LRKKKSIH 107

  Fly    77 GDLYVNSVDELPEEFDSRKQWPNCPTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFS 141
            ..::    ..||:..|    |.....:..:::||:|.|||||....|:..::...:|..|:  .|
  Rat   108 QPIF----RYLPKFVD----WRRRGYVTSVKNQGTCNSCWAFSVAGAIEGQMFRKTGRLVS--LS 162

  Fly   142 ADDLVSCCHTCG-FGCNGGFPGAAWSY-WTRKGIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPC 204
            ..:||.|....| .||:.|....|..| |:..|:.:...|       |||         |...||
  Rat   163 PQNLVDCSRPEGNHGCHMGSTLYALKYVWSNGGLEAESTY-------PYE---------GKEGPC 211

  Fly   205 AHGGRTPKCSHVCQSGYTVDYAKDKHFGSKSYSVRRNVREIQEEIMTNGPVE-GAFTVYEDLILY 268
            .:   .|:.|....:|::              :|.|:...:...:.|.||:. |....:.....|
  Rat   212 RY---LPRRSAARVTGFS--------------TVARSEEALMHAVATIGPISVGIDASHVSFRFY 259

  Fly   269 KDGVYQHEH-GKELGGHAIRILGWGVWGEEK--IPYWLIGNSWNTDWGDHGFFRILRG-QDHCGI 329
            :.|:|.... ......|::.::|:|..|.|.  ..||||.||....||.:|:.::.|| .:||||
  Rat   260 RRGIYYEPRCSSNRINHSVLVVGYGYEGRESDGRKYWLIKNSHGVGWGMNGYMKLARGWNNHCGI 324

  Fly   330  329
              Rat   325  324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358	11/46 (24%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	65/249 (26%)
Cts8	NP_001121688.1	PTZ00203	5..327	CDD:185513	80/325 (25%)
		Inhibitor_I29	29..87	CDD:214853	9/40 (23%)
		Peptidase_C1A	115..331	CDD:239068	65/249 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910