Protein Alignment CtsB1 and Ctsm

DIOPT Version :9

• Sequence 1: NP_001259536.2
• Gene: CtsB1 / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_001347650.1
• Gene: Ctsm / 64139
• MGIID: 1927229
• Length: 333
• Species: Mus musculus
• Alignment Length: 366
• Identity: 84/366 - (22%)
• Similarity: 149/366 - (40%)
• Gaps: 85/366 - (23%)

  Fly     7 VATAASVAALTSGE--PSLLSDEFIEVVRSKAKTWTV--GRNFD-------ASVTEGHIRRL--- 57
            :.:|..:|.|..|.  ||...|..::|...|   |.:  |:.:.       .:|.|.:::::
Mouse     1 MTSAIFLAMLCLGMALPSPAPDPILDVEWQK---WKIKYGKAYSLEEEGQKRAVWEDNMKKIKLH 62

  Fly    58 -----MGVH---PDAHKF---ALPDKREVLGDLYVNSVDE-----------LPEEFDSRKQWPNC 100
                 :|.|   .:.:.|   .|.:.|:|:.::.|.:|.:           ||:..:    |...
Mouse    63 NGENGLGKHGFTMEMNAFGDMTLEEFRKVMIEIPVPTVKKGKSVQKRLSVNLPKFIN----WKKR 123

  Fly   101 PTIGEIRDQGSCGSCWAFGAVEAMSDRVCIHSGGKVNFHFSADDLVSCCHTCG-FGCNGGFPGAA 164
            ..:..::.||.|.|||||....|:..::...:|..:  ..|..:||.|....| :||..|....|
Mouse   124 GYVTPVQTQGRCNSCWAFSVTGAIEGQMFRKTGQLI--PLSVQNLVDCSRPQGNWGCYLGNTYLA 186

  Fly   165 WSY-WTRKGIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPCAHGGRTPKCSHVCQSGYTVDYAKD 228
            ..| ....|:.|...|       |||      ..:|:   |.:   :|:.|....:|:..
Mouse   187 LHYVMENGGLESEATY-------PYE------EKDGS---CRY---SPENSTANITGFEF----- 227

  Fly   229 KHFGSKSYSVRRNVREIQEEIMTNGPVEGAFTV-YEDLILYKDGVYQHEH-GKELGGHAIRILGW 291
                     |.:|...:...:.:.||:..|... :...:.||.|:|...: ...:..|::.::|:
Mouse   228 ---------VPKNEDALMNAVASIGPISVAIDARHASFLFYKRGIYYEPNCSSSVVTHSMLLVGY 283

  Fly   292 GVWGEEK--IPYWLIGNSWNTDWGDHGFFRILRGQ-DHCGI 329
            |..|.|.  ..|||:.||..|.||:.|:.:|.|.: :||||
Mouse   284 GFTGRESDGRKYWLVKNSMGTQWGNKGYMKISRDKGNHCGI 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358	9/59 (15%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	62/249 (25%)
Ctsm	NP_001347650.1	Inhibitor_I29	29..87	CDD:214853	9/60 (15%)
		Peptidase_C1A	115..331	CDD:239068	62/249 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910