Protein Alignment CtsB1 and Cts6

DIOPT Version :9

• Sequence 1: NP_001259536.2
• Gene: CtsB1 / 32341
• FlyBaseID: FBgn0030521
• Length: 340
• Species: Drosophila melanogaster
• Sequence 2: NP_067420.1
• Gene: Cts6 / 58518
• MGIID: 1889619
• Length: 334
• Species: Mus musculus
• Alignment Length: 301
• Identity: 86/301 - (28%)
• Similarity: 124/301 - (41%)
• Gaps: 58/301 - (19%)

  Fly    39 WTVGRNFDASVTEGHIRRLMGVHPD-AHKFALPDKREVLGDLYVNSVDELPEEFDSRKQWPNCPT 102
            :|:..|....:|...:|::|...|. :||     ||:::....|.  |.||:..|.||:    ..
Mouse    73 FTLKMNEFGDLTPEELRKMMNNFPIWSHK-----KRKIIRKRAVG--DVLPKFVDWRKK----GY 126

  Fly   103 IGEIRDQGSCGSCWAF---GAVEAMSDRVCIHSGGKVNFHFSADDLVSCCHTCG-FGCNGGFPGA 163
            :..:|.|..|.|||||   ||:|..    .....||:. ..|..:||.|..|.| .||..|.|..
Mouse   127 VTRVRRQKFCNSCWAFAVNGAIEGQ----MFKKTGKLT-PLSVQNLVDCTKTQGNDGCQWGDPYI 186

  Fly   164 AWSYWTRKGIVSGGPYGSNQGCRPYEISPCEHHVNGTRPPCAHGGRTPKCSHVCQSGYTVDYAKD 228
            |:.|....|.:..      :...|||         |...||.:   .||.|....:|:.
Mouse   187 AYEYVLNNGGLEA------EATYPYE---------GKEGPCRY---NPKNSKAEITGFV------ 227

  Fly   229 KHFGSKSYSVRRNVREIQEEIMTNGPVEGAFTV-YEDLILYKDGVY-QHEHGKELGGHAIRILGW 291
                    |:..:...:.|.:.|.||:..|... :.....|..|:| |.........||:.::|:
Mouse   228 --------SLPESEDILMEAVATIGPISAAVDASFNRFSFYDGGIYHQPNCSNNTVNHAVLVVGY 284

  Fly   292 GVWGEEK--IPYWLIGNSWNTDWGDHGFFRILRGQ-DHCGI 329
            |..|.|.  ..||||.|||...||..|:.:|:|.| :||||
Mouse   285 GTEGNETDGNKYWLIKNSWGRRWGIGGYMKIIRDQNNHCGI 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CtsB1	NP_001259536.2	Propeptide_C1	24..64	CDD:285358	6/25 (24%)
		Peptidase_C1A_CathepsinB	88..336	CDD:239111	73/251 (29%)
Cts6	NP_067420.1	PTZ00203	7..332	CDD:185513	86/301 (29%)
		Inhibitor_I29	29..87	CDD:214853	3/13 (23%)
		Peptidase_C1A	116..332	CDD:239068	73/251 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG4870
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53545
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910